PMID- 31164686
OWN - NLM
STAT- MEDLINE
DCOM- 20201026
LR  - 20210109
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 9
IP  - 1
DP  - 2019 Jun 4
TI  - Quality of life after photo-selective vaporization and holmium-laser enucleation 
      of the prostate: 5-year outcomes.
PG  - 8261
LID - 10.1038/s41598-019-44686-2 [doi]
LID - 8261
AB  - This study was aimed to compare serial long-term postoperative changes in 
      quality-of-life (QoL) between photoselective-vaporization (PVP) using 
      120W-High-Performance-System and holmium-laser-enucleation (HoLEP) in 
      benign-prostatic-hyperplasia (BPH) patients and to identify factors influencing 
      the QoL improvement at the short-term, mid-term and long-term follow-up visits 
      after surgery. We analyzed 1,193 patients with a baseline QoL-index >/=2 who 
      underwent PVP (n = 439) or HoLEP (n = 754). Surgical outcomes were serially 
      compared between the two groups at up to 60-months using the 
      International-Prostatic-Symptom-Score (I-PSS), uroflowmetry, and serum PSA. We 
      used logistic regression analysis to identify predictors of QoL improvement (a 
      reduction in the QoL-index >/=50% compared with baseline) at the short-term 
      (12-months), mid-term (36-months), and long term (60-months) follow-up after 
      surgery. In both groups, the QoL-index was decreased throughout the entire 
      follow-up period compared with that at baseline. There were no significant 
      differences in postoperative changes from the baseline QoL-index between the two 
      groups during the 48-month follow-up, except at 60-months. The degree of 
      improvement in QoL at 60-months after HoLEP was greater than that after PVP. A 
      lower baseline storage-symptom-subscore and a higher 
      bladder-outlet-obstruction-index (BOOI) were independent factors influencing QoL 
      improvement at the short-term. No independent factor influences QoL improvement 
      at the mid- or long-term.
FAU - Sun, Inyoung
AU  - Sun I
AD  - Department of Urology, Seoul National University College of Medicine, Seoul 
      National University Hospital, Seoul, 03080, Republic of Korea.
FAU - Yoo, Sangjun
AU  - Yoo S
AD  - Department of Urology, Seoul National University College of Medicine, SMG-SNU 
      Boramae Medical Center, Seoul, 07061, Republic of Korea.
FAU - Park, Juhyun
AU  - Park J
AD  - Department of Urology, Seoul National University College of Medicine, SMG-SNU 
      Boramae Medical Center, Seoul, 07061, Republic of Korea.
FAU - Cho, Sung Yong
AU  - Cho SY
AD  - Department of Urology, Seoul National University College of Medicine, SMG-SNU 
      Boramae Medical Center, Seoul, 07061, Republic of Korea.
FAU - Jeong, Hyeon
AU  - Jeong H
AD  - Department of Urology, Seoul National University College of Medicine, SMG-SNU 
      Boramae Medical Center, Seoul, 07061, Republic of Korea.
FAU - Son, Hwancheol
AU  - Son H
AD  - Department of Urology, Seoul National University College of Medicine, SMG-SNU 
      Boramae Medical Center, Seoul, 07061, Republic of Korea.
FAU - Oh, Seung-June
AU  - Oh SJ
AUID- ORCID: 0000-0002-0322-3539
AD  - Department of Urology, Seoul National University College of Medicine, Seoul 
      National University Hospital, Seoul, 03080, Republic of Korea.
FAU - Paick, Jae-Seung
AU  - Paick JS
AD  - Department of Urology, Seoul National University College of Medicine, Seoul 
      National University Hospital, Seoul, 03080, Republic of Korea.
FAU - Cho, Min Chul
AU  - Cho MC
AUID- ORCID: 0000-0001-7288-1706
AD  - Department of Urology, Seoul National University College of Medicine, SMG-SNU 
      Boramae Medical Center, Seoul, 07061, Republic of Korea. cmc1206@empal.com.
LA  - eng
PT  - Journal Article
DEP - 20190604
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
EIN - Sci Rep. 2019 Nov 8;9(1):16722. PMID: 31705035
MH  - Aged
MH  - Humans
MH  - Laser Therapy/adverse effects/*methods
MH  - Lasers, Solid-State/adverse effects/*therapeutic use
MH  - Lower Urinary Tract Symptoms/epidemiology/pathology/*surgery
MH  - Male
MH  - Middle Aged
MH  - Postoperative Period
MH  - Prostate/pathology/surgery
MH  - Prostatic Hyperplasia/epidemiology/pathology/*surgery
MH  - Quality of Life
MH  - Transurethral Resection of Prostate/adverse effects
MH  - Treatment Outcome
PMC - PMC6547661
COIS- The authors declare no competing interests.
EDAT- 2019/06/06 06:00
MHDA- 2020/10/27 06:00
PMCR- 2019/06/04
CRDT- 2019/06/06 06:00
PHST- 2019/02/15 00:00 [received]
PHST- 2019/05/22 00:00 [accepted]
PHST- 2019/06/06 06:00 [entrez]
PHST- 2019/06/06 06:00 [pubmed]
PHST- 2020/10/27 06:00 [medline]
PHST- 2019/06/04 00:00 [pmc-release]
AID - 10.1038/s41598-019-44686-2 [pii]
AID - 44686 [pii]
AID - 10.1038/s41598-019-44686-2 [doi]
PST - epublish
SO  - Sci Rep. 2019 Jun 4;9(1):8261. doi: 10.1038/s41598-019-44686-2.