PMID- 31165930
OWN - NLM
STAT- MEDLINE
DCOM- 20200302
LR  - 20200302
IS  - 1435-1250 (Electronic)
IS  - 0340-1855 (Linking)
VI  - 79
IP  - 1
DP  - 2020 Feb
TI  - Neuropathic pain in ankylosing spondylitis: a meta-analysis.
PG  - 95-102
LID - 10.1007/s00393-019-0654-3 [doi]
AB  - AIM: The aim of this study was to compare demographic characteristics, disease 
      activity, functional status, and quality of life between ankylosing spondylitis 
      (AS) with neuropatic pain (NP) and AS without NP (Non-NP). METHODS: The MEDLINE 
      via PubMed, Cochrane, Scopus, and Embase database, from the earliest available 
      date of indexing through December 20, 2018, were searched for comparative studies 
      evaluating NP in AS patients. Two authors performed the data extraction 
      independently. Any discrepancies were resolved by consensus. RESULTS: Four 
      comparative studies were identified. There was no statistically significant 
      difference in terms of age, body mass index, symptom duration, and inflammatory 
      markers, such as erythrocyte sedimentation rate and C‑reactive protein between NP 
      and Non-NP. The sex ratios (F/M) were approximately 1/1 in NP and 1/2 in Non-NP 
      and the proportion of human leukocyte antigen (HLA) B27-positive patients in NP 
      and Non-NP was 65.7% and 83.0%, respectively. NP patients had significantly 
      higher visual analogue scale pain scores, higher Bath Ankylosing Spondylitis 
      Disease Activity Index, higher Bath Ankylosing Spondylitis Functional Index, and 
      lower SF-Item Short Form physical component scores compare to Non-NP patients. 
      CONCLUSION: The current meta-analysis showed that NP patients had significantly 
      higher pain severity, higher disease activity and lower quality of life than 
      Non-NP patients. The sex ratio (F/M) and proportion of HLA-B27 positive patients 
      were different between the two groups. Further well-designed studies are needed 
      to substantiate our results.
FAU - Kim, T W
AU  - Kim TW
AD  - Department of Orthopaedic Surgery, Bonebarum Hospital, Yangsan, Korea (Republic 
      of).
FAU - Son, S M
AU  - Son SM
AD  - BioMedical Research Institute, Department of Orthopaedic Surgery, Pusan National 
      University Yangsan Hospital, Yangsan, Korea (Republic of).
FAU - Lee, J S
AU  - Lee JS
AD  - BioMedical Research Institute, Department of Orthopaedic Surgery, Pusan National 
      University Hospital, 179 Gudeok-Ro, Seo-Gu, 49241, Busan, Korea (Republic of). 
      jungsublee@pusan.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
TT  - Neuropathischer Schmerz bei ankylosierender Spondylitis - eine Metaanalyse.
PL  - Germany
TA  - Z Rheumatol
JT  - Zeitschrift fur Rheumatologie
JID - 0414162
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Adult
MH  - Blood Sedimentation
MH  - C-Reactive Protein
MH  - Female
MH  - Humans
MH  - Male
MH  - *Neuralgia/etiology
MH  - *Quality of Life
MH  - Severity of Illness Index
MH  - *Spondylitis, Ankylosing/complications
OTO - NOTNLM
OT  - Ankylosing spondylitis
OT  - Disease activity
OT  - Meta-analysis
OT  - Neuropathic pain
OT  - Quality of life
EDAT- 2019/06/06 06:00
MHDA- 2020/03/03 06:00
CRDT- 2019/06/06 06:00
PHST- 2019/06/06 06:00 [pubmed]
PHST- 2020/03/03 06:00 [medline]
PHST- 2019/06/06 06:00 [entrez]
AID - 10.1007/s00393-019-0654-3 [pii]
AID - 10.1007/s00393-019-0654-3 [doi]
PST - ppublish
SO  - Z Rheumatol. 2020 Feb;79(1):95-102. doi: 10.1007/s00393-019-0654-3.