PMID- 31172584
OWN - NLM
STAT- MEDLINE
DCOM- 20200109
LR  - 20200109
IS  - 1600-0714 (Electronic)
IS  - 0904-2512 (Linking)
VI  - 48
IP  - 7
DP  - 2019 Aug
TI  - Quality of life in patients with oral leukoplakia.
PG  - 574-580
LID - 10.1111/jop.12897 [doi]
AB  - BACKGROUND: Oral leukoplakia (OL) is the most common oral potentially malignant 
      disorder, yet despite its chronic and potentially disabling nature, the 
      literature concerning impacts of OL on quality of life (QoL) is limited. This 
      study aimed to evaluate QoL in subjects with OL compared to controls using QoL 
      questionnaires. METHODS: Fifty individuals with OL and 50 controls matched for 
      age, gender, smoking, and alcohol use were administered the Short Generic Health 
      Questionnaire (SF-12) and the discipline-specific Oral Potentially Malignant 
      Disorder Questionnaire (OPMDQ). Responses were compared between the two groups. 
      RESULTS: Subjects with OL reported poorer QoL scores compared to controls in two 
      domains "Role limitations due to physical problems" and "Pain" of the SF-12 
      questionnaire, and in two domains "Difficulty with diagnosis" and "Effect of 
      treatment on daily life" and in the overall scores of the OPMDQ. Females reported 
      poorer QoL in the overall OPMD QoL score and in the domains of "Physical and 
      function limitation" and "Psychological and social well-being," while older 
      individuals in the domains of "Physical and function limitation" and "Effect of 
      treatment on daily life." Non-alcohol drinkers and subjects with dysplastic or 
      non-homogeneous OLs also reported poorer QoL scores. CONCLUSIONS: Quality of life 
      assessments provide useful insight into the impact of OL on an individual's life 
      and opportunity to improve clinical care.
CI  - (c) 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Min Ang, Xin
AU  - Min Ang X
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
FAU - Chi Khang Au, Phil
AU  - Chi Khang Au P
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
FAU - Kwok, Kevin
AU  - Kwok K
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
FAU - Yeon Park, Ka
AU  - Yeon Park K
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
FAU - Kujan, Omar
AU  - Kujan O
AUID- ORCID: 0000-0002-5951-8280
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
FAU - Frydrych, Agnieszka M
AU  - Frydrych AM
AUID- ORCID: 0000-0001-5301-4148
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
FAU - Farah, Camile S
AU  - Farah CS
AUID- ORCID: 0000-0002-1642-6204
AD  - UWA Dental School, University of Western Australia, Nedlands, Western Australia, 
      Australia.
AD  - Australian Centre for Oral Oncology Research & Education, Nedlands, Western 
      Australia, Australia.
LA  - eng
PT  - Journal Article
DEP - 20190626
PL  - Denmark
TA  - J Oral Pathol Med
JT  - Journal of oral pathology & medicine : official publication of the International 
      Association of Oral Pathologists and the American Academy of Oral Pathology
JID - 8911934
SB  - IM
MH  - Female
MH  - Humans
MH  - *Leukoplakia, Oral
MH  - *Mouth Diseases
MH  - *Quality of Life
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - case-control studies
OT  - mouth neoplasms
OT  - oral leukoplakia
OT  - quality of life
EDAT- 2019/06/07 06:00
MHDA- 2020/01/10 06:00
CRDT- 2019/06/08 06:00
PHST- 2019/06/05 00:00 [received]
PHST- 2019/06/05 00:00 [accepted]
PHST- 2019/06/07 06:00 [pubmed]
PHST- 2020/01/10 06:00 [medline]
PHST- 2019/06/08 06:00 [entrez]
AID - 10.1111/jop.12897 [doi]
PST - ppublish
SO  - J Oral Pathol Med. 2019 Aug;48(7):574-580. doi: 10.1111/jop.12897. Epub 2019 Jun 
      26.