PMID- 31173084
OWN - NLM
STAT- Publisher
LR  - 20240402
IS  - 1525-3163 (Electronic)
IS  - 0021-8812 (Print)
IS  - 0021-8812 (Linking)
VI  - 97
IP  - 8
DP  - 2019 Jun 6
TI  - Identification of resilient sows in Porcine Reproductive and Respiratory Syndrome 
      virus infected farms.
PG  - 3228-36
LID - skz192 [pii]
LID - 10.1093/jas/skz192 [doi]
AB  - The identification of resilient sows can improve reproductive performance in 
      farms exposed to multiple challenges. A common challenge is the porcine 
      reproductive and respiratory syndrome virus (PRRSV). A key issue to deal with 
      disease resilience is to set up a feasible phenotyping strategy. Our aim was to 
      develop a phenotyping criterion to discriminate susceptible from resilient sows 
      in PRRSV-infected farms. A total of 517 Landrace x Large White gilts were 
      classified as resilient (R) or susceptible (S) to PRRSV virus, following 
      vaccination with MLV-PRRSV at 6-7 wk of age, in a PRRSV negative multiplication 
      farm. Female piglets were phenotyped as R if their serum was negative to PRRSV at 
      7 and 21 d post-vaccination (DPV) or as S if their serum was positive at 7 and/or 
      21 DPV. Amongst them, 382 gilts were transferred to a PRRSV-positive production 
      farm, where the number of piglets born alive (NBA), stillborn (NSB), mummified 
      (NMU), lost (NLP=NSB+NMU) and total born (NTB = NBA+NLP) were recorded for almost 
      three years. Data were collected during two periods according to the PRRSV farm 
      health status, which were confirmed as either PRRSV-positive stable (endemic) or 
      inestable (epidemic). Analyses were carried out under a Bayesian approach. The 
      heritability for the resilience criterion was estimated using a threshold model. 
      A linear (for NTB and NBA) and a binomial model (for NSB, NMU and NLP) on the 
      resilience criterion by the farm health status were used to assess the difference 
      between R and S sows. The heritability of the resilience criterion was 0.46 (SD 
      0.06). The probability of a piglet being lost was greater (>/=0.97) in S than in R 
      litters, regardless of whether the delivery occurred during a PRRSV outbreak 
      (20.5% vs 17.0%) or not (15.8% vs 13.7%). The lower piglet mortality rate in R 
      sows was due to NSB, in the endemic phase (13.0% vs 15.0% of NTB, with a 
      posterior probability of 98% of S sows showing higher NSB than R sows), and to 
      NMU, in the epidemic phase (4.0% vs 8.4% of NTB, with a posterior probability of 
      >99% of S sows showing higher NMU than R sows). During a PRRSV outbreak, the S 
      sows were twice as likely to give birth to a mummified piglet as compared to R 
      sows. These findings provide evidence that the described phenotyping scheme has a 
      potential use as a PRRSV resilience criterion.
CI  - (c) The Author(s) 2019. Published by Oxford University Press on behalf of the 
      American Society of Animal Science. All rights reserved. For permissions, please 
      e-mail: journals.permissions@oup.com.
FAU - Abella, Gloria
AU  - Abella G
AD  - Departament de Ciencia Animal, University of Lleida-Agrotecnio Center, Lleida, 
      Spain.
FAU - Novell, Elena
AU  - Novell E
AD  - Departament de Ciencia Animal, University of Lleida-Agrotecnio Center, Lleida, 
      Spain.
AD  - Grup de Saneajament Porci, Lleida, Spain.
FAU - Tarancon, Vicenc
AU  - Tarancon V
AD  - Grup de Saneajament Porci, Lleida, Spain.
FAU - Varona, Luis
AU  - Varona L
AD  - Instituto Agroalimentario de Aragon (IA2). Universidad de Zaragoza, Zaragoza, 
      Spain.
FAU - Pena, Ramona N
AU  - Pena RN
AD  - Departament de Ciencia Animal, University of Lleida-Agrotecnio Center, Lleida, 
      Spain.
FAU - Estany, Joan
AU  - Estany J
AD  - Departament de Ciencia Animal, University of Lleida-Agrotecnio Center, Lleida, 
      Spain.
FAU - Fraile, Lorenzo
AU  - Fraile L
AD  - Departament de Ciencia Animal, University of Lleida-Agrotecnio Center, Lleida, 
      Spain.
LA  - eng
PT  - Journal Article
DEP - 20190606
PL  - United States
TA  - J Anim Sci
JT  - Journal of animal science
JID - 8003002
PMC - PMC6667243
OTO - NOTNLM
OT  - PRRSV
OT  - phenotyping method
OT  - resilience
OT  - sow
EDAT- 2019/06/08 06:00
MHDA- 2019/06/08 06:00
PMCR- 2020/07/30
CRDT- 2019/06/08 06:00
PHST- 2019/03/13 00:00 [received]
PHST- 2019/06/08 06:00 [entrez]
PHST- 2019/06/08 06:00 [pubmed]
PHST- 2019/06/08 06:00 [medline]
PHST- 2020/07/30 00:00 [pmc-release]
AID - 5512407 [pii]
AID - skz192 [pii]
AID - 10.1093/jas/skz192 [doi]
PST - aheadofprint
SO  - J Anim Sci. 2019 Jun 6;97(8):3228-36. doi: 10.1093/jas/skz192.