PMID- 31173476
OWN - NLM
STAT- MEDLINE
DCOM- 20200624
LR  - 20200624
IS  - 1520-6033 (Electronic)
IS  - 1520-6033 (Linking)
VI  - 35
IP  - 5
DP  - 2019 Sep
TI  - Efficient succinic acid production from high-sugar-content beverages by 
      Actinobacillus succinogenes.
PG  - e2863
LID - 10.1002/btpr.2863 [doi]
AB  - This study presents the production of succinic acid (SA) by Actinobacillus 
      succinogenes using high-sugar-content beverages (HSCBs) as feedstock. The aim of 
      this study was the valorization of a by-product stream from the beverage industry 
      for the production of an important building block chemical, such as SA. Three 
      types of commercial beverages were investigated: fruit juices (pineapple and 
      ace), syrups (almond), and soft drinks (cola and lemon). They contained mainly 
      glucose, fructose, and sucrose at high concentration-between 50 and 1,000 g/L. 
      The batch fermentation tests highlighted that A. succinogenes was able to grow on 
      HSCBs supplemented with yeast extract, but also on the unsupplemented fruit 
      juices. Indeed, the bacteria did not grow on the unsupplemented syrup and soft 
      drinks because of the lack of indispensable nutrients. About 30-40 g/L of SA were 
      obtained, depending on the type of HSCB, with yield ranging between 0.75 and 
      1.00 g(SA) /g(S) . The prehydrolysis step improved the fermentation performance: 
      SA production was improved by 6-24%, depending on the HSCB, and sugar conversion 
      was improved of about 30-50%.
CI  - (c) 2019 American Institute of Chemical Engineers.
FAU - Ferone, Mariateresa
AU  - Ferone M
AUID- ORCID: 0000-0003-1266-5424
AD  - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, 
      Universita degli Studi di Napoli Federico II, Naples, Italy.
FAU - Ercole, Alessia
AU  - Ercole A
AD  - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, 
      Universita degli Studi di Napoli Federico II, Naples, Italy.
FAU - Raganati, Francesca
AU  - Raganati F
AD  - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, 
      Universita degli Studi di Napoli Federico II, Naples, Italy.
FAU - Olivieri, Giuseppe
AU  - Olivieri G
AD  - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, 
      Universita degli Studi di Napoli Federico II, Naples, Italy.
FAU - Salatino, Piero
AU  - Salatino P
AD  - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, 
      Universita degli Studi di Napoli Federico II, Naples, Italy.
FAU - Marzocchella, Antonio
AU  - Marzocchella A
AUID- ORCID: 0000-0002-8124-9419
AD  - Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, 
      Universita degli Studi di Napoli Federico II, Naples, Italy.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190619
PL  - United States
TA  - Biotechnol Prog
JT  - Biotechnology progress
JID - 8506292
RN  - 0 (Dietary Sugars)
RN  - AB6MNQ6J6L (Succinic Acid)
SB  - IM
MH  - Actinobacillus/*metabolism
MH  - *Beverages
MH  - Bioreactors/microbiology
MH  - Dietary Sugars/*metabolism
MH  - Fermentation
MH  - *Succinic Acid/analysis/metabolism
OTO - NOTNLM
OT  - Actinobacillus succinogenes
OT  - biorefinery
OT  - fermentation
OT  - high-content-sugar beverages
OT  - succinic acid
EDAT- 2019/06/08 06:00
MHDA- 2020/06/25 06:00
CRDT- 2019/06/08 06:00
PHST- 2018/12/18 00:00 [received]
PHST- 2019/05/30 00:00 [revised]
PHST- 2019/06/03 00:00 [accepted]
PHST- 2019/06/08 06:00 [pubmed]
PHST- 2020/06/25 06:00 [medline]
PHST- 2019/06/08 06:00 [entrez]
AID - 10.1002/btpr.2863 [doi]
PST - ppublish
SO  - Biotechnol Prog. 2019 Sep;35(5):e2863. doi: 10.1002/btpr.2863. Epub 2019 Jun 19.