PMID- 31176474
OWN - NLM
STAT- MEDLINE
DCOM- 20201023
LR  - 20201023
IS  - 1872-6968 (Electronic)
IS  - 0303-8467 (Linking)
VI  - 184
DP  - 2019 Sep
TI  - Optic canal size in idiopathic intracranial hypertension and asymmetric 
      papilledema.
PG  - 105376
LID - S0303-8467(19)30164-7 [pii]
LID - 10.1016/j.clineuro.2019.105376 [doi]
AB  - OBJECTIVE: Asymmetric papilledema (AP) is a rare condition in idiopathic 
      intracranial hypertension (IIH). As the pathophysiology of papilledema 
      developement in IIH remains unclear, the study of AP could clarify some etiologic 
      aspects. We aimed to evaluate bony optic canal size in IIH patients with AP. 
      PATIENTS AND METHODS: All IIH patients based on modified Dandy criteria in our 
      referral tertiary eye hospital underwent neuro-opthalmologic exams and grading of 
      papilledema according to modified Frisen scale. Very asymmetric papilledema (VAP) 
      defined as a >/=2 grade difference between the two eyes. Clinical features, 
      cerebrospinal fluid opening pressure (CSF OP), best corrected visual acuity, 
      Humphery visual field, and brain magnetic resonance imaging (MRI) and MR 
      venography was performed for all patients. Spiral orbital computed tomography 
      (CT) scan which is the choice method for details of bony structures with axial, 
      coronal and sagittal planes was done in patients with VAP. RESULT: 59 patients 
      with IIH were diagnosed that 18.6% of them (n = 11) had VAP. There was no IIH 
      patient with strictly unilateral Papilledema. Presenting symptoms and CSF OP was 
      not significantly different between patients with symmetric and asymmetric 
      papilledema. In patients with VAP, bony optic canal size was not statistically 
      significant different in axial, coronal and sagittal plane when comparing the eye 
      with higher grade edema to the fellow eye. CONCLUSION: Our study showed that bony 
      optic canal size evaluated by orbital CT scan was not different in VAP in IIH 
      patients. Finding the exact pathophysiology of AP need further studies.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Farrokhi, Yasin
AU  - Farrokhi Y
AD  - Department of Radiology, Emam Khomeini Hospital, Urmia University of Medical 
      Sciences, Urmia, Iran.
FAU - Sharif Kashani, Shervin
AU  - Sharif Kashani S
AD  - Department of Radiology, Farabi Eye Hospital, Tehran University of Medical 
      Sciences, Tehran, Iran. Electronic address: kashanis@sina.tums.ac.ir.
FAU - Aghsaei Fard, Masoud
AU  - Aghsaei Fard M
AD  - Department of Neuro-ophthalmology and Strabismus, Farabi Eye Hospital, Tehran 
      University of Medical Sciences, Tehran, Iran; Eye Research Center, Farabi Eye 
      Hospital, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Pakdel, Farzad
AU  - Pakdel F
AD  - Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, 
      Tehran, Iran; Department of Orbit and Oculoplastic Surgery, Farabi Eye Hospital, 
      Tehran University of Medical Sciences, Tehran, Iran.
FAU - Yadegari, Samira
AU  - Yadegari S
AD  - Department of Neuro-ophthalmology and Strabismus, Farabi Eye Hospital, Tehran 
      University of Medical Sciences, Tehran, Iran; Eye Research Center, Farabi Eye 
      Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic 
      address: yadegarisamira@yahoo.com.
LA  - eng
PT  - Journal Article
DEP - 20190522
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Optic Chiasm/*diagnostic imaging
MH  - Papilledema/complications/*diagnostic imaging
MH  - Pseudotumor Cerebri/complications/*diagnostic imaging
OTO - NOTNLM
OT  - Asymmetric papilledema
OT  - Idiopathic intracranial hypertension
OT  - Optic canal
EDAT- 2019/06/10 06:00
MHDA- 2020/10/24 06:00
CRDT- 2019/06/10 06:00
PHST- 2018/07/29 00:00 [received]
PHST- 2019/05/12 00:00 [revised]
PHST- 2019/05/21 00:00 [accepted]
PHST- 2019/06/10 06:00 [pubmed]
PHST- 2020/10/24 06:00 [medline]
PHST- 2019/06/10 06:00 [entrez]
AID - S0303-8467(19)30164-7 [pii]
AID - 10.1016/j.clineuro.2019.105376 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2019 Sep;184:105376. doi: 10.1016/j.clineuro.2019.105376. 
      Epub 2019 May 22.