PMID- 31177635 OWN - NLM STAT- MEDLINE DCOM- 20210111 LR - 20210111 IS - 1751-7893 (Electronic) IS - 1751-7885 (Print) IS - 1751-7885 (Linking) VI - 14 IP - 2 DP - 2020 Apr TI - Theatre improvisation training to promote social cognition: A novel recovery-oriented intervention for youths at clinical risk for psychosis. PG - 163-171 LID - 10.1111/eip.12834 [doi] AB - AIM: Few interventions address social cognition or functioning in individuals at clinical risk (CR) for psychosis. Theatre Improvisation Training to Promote Social Cognition (TIPS) is a manualized intervention based on drama therapy. We aim to describe TIPS, evaluate feasibility and acceptability, and present a preliminary investigation of outcomes in a quasi-experimental design. METHODS: Thirty-six CR participants (15-25 years) were ascertained from the Philadelphia Neurodevelopmental Cohort. Twenty-six completed the TIPS protocol: 18 weekly 2-hour group sessions led by a theatre director and actor-assistant. Participants engaged in collaborative acting and improvisation exercises. Baseline and follow-up assessments included the Clinical Assessment Interview for Negative Symptoms (CAINS), Structured Interview for Prodromal Syndromes, Global Assessment of Functioning (GAF) and Penn Computerized Neurocognitive Battery (CNB), which includes social cognitive tests. Acceptability was assessed using focus groups. Preliminary outcomes were compared to CR controls who were not enrolled in the study but completed follow-up assessments using the same methods. RESULTS: There were no significant differences in baseline demographics, psychosis symptoms, or cognition between those who did and did not complete the protocol. Overall, TIPS was considered feasible and acceptable among CR. Preliminary outcomes suggest that TIPS may be effective in improving positive and negative psychosis-spectrum symptoms and GAF, but not performance on facial emotion processing. CONCLUSIONS: TIPS is a promising and acceptable intervention that may improve symptoms and functioning in CR while providing a framework for participants to develop more empowered and confident ways of relating to others. Larger randomized controlled trials investigating TIPS efficacy are warranted. CI - (c) 2019 John Wiley & Sons Australia, Ltd. FAU - Tang, Sunny X AU - Tang SX AUID- ORCID: 0000-0002-4001-8120 AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. AD - University of Pennsylvania and Children's Hospital of Philadelphia, Lifespan Brain Institute, Philadelphia, Pennsylvania. FAU - Seelaus, Kevin H AU - Seelaus KH AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Moore, Tyler M AU - Moore TM AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. AD - University of Pennsylvania and Children's Hospital of Philadelphia, Lifespan Brain Institute, Philadelphia, Pennsylvania. FAU - Taylor, Jerome AU - Taylor J AD - Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. AD - University of Pennsylvania and Children's Hospital of Philadelphia, Lifespan Brain Institute, Philadelphia, Pennsylvania. FAU - Moog, Carol AU - Moog C AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - O'Connor, David AU - O'Connor D AD - Theater Arts Program, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Burkholder, Marla AU - Burkholder M AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Kohler, Christian G AU - Kohler CG AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Grant, Paul M AU - Grant PM AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Eliash, Dvora AU - Eliash D AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. FAU - Calkins, Monica E AU - Calkins ME AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. AD - University of Pennsylvania and Children's Hospital of Philadelphia, Lifespan Brain Institute, Philadelphia, Pennsylvania. FAU - Gur, Raquel E AU - Gur RE AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. AD - Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. AD - University of Pennsylvania and Children's Hospital of Philadelphia, Lifespan Brain Institute, Philadelphia, Pennsylvania. FAU - Gur, Ruben C AU - Gur RC AUID- ORCID: 0000-0002-9657-1996 AD - Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania. AD - Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. AD - University of Pennsylvania and Children's Hospital of Philadelphia, Lifespan Brain Institute, Philadelphia, Pennsylvania. LA - eng GR - L30 MH111007/MH/NIMH NIH HHS/United States GR - R34 MH105248/MH/NIMH NIH HHS/United States GR - T32 MH019112/MH/NIMH NIH HHS/United States PT - Controlled Clinical Trial PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20190609 PL - Australia TA - Early Interv Psychiatry JT - Early intervention in psychiatry JID - 101320027 SB - IM MH - Adolescent MH - Adult MH - Cohort Studies MH - Female MH - Humans MH - Male MH - Prodromal Symptoms MH - Psychodrama/*methods MH - Psychotherapy, Group MH - Psychotic Disorders/psychology/*therapy MH - *Social Cognition MH - Young Adult PMC - PMC7446755 MID - NIHMS1592202 OTO - NOTNLM OT - cognition OT - prodromal symptoms OT - psychotic disorders OT - schizophrenia OT - therapeutics COIS- CONFLICT OF INTEREST All listed authors have no financial disclosures. EDAT- 2019/06/10 06:00 MHDA- 2021/01/12 06:00 PMCR- 2020/08/25 CRDT- 2019/06/10 06:00 PHST- 2018/11/07 00:00 [received] PHST- 2019/02/19 00:00 [revised] PHST- 2019/04/14 00:00 [accepted] PHST- 2019/06/10 06:00 [pubmed] PHST- 2021/01/12 06:00 [medline] PHST- 2019/06/10 06:00 [entrez] PHST- 2020/08/25 00:00 [pmc-release] AID - 10.1111/eip.12834 [doi] PST - ppublish SO - Early Interv Psychiatry. 2020 Apr;14(2):163-171. doi: 10.1111/eip.12834. Epub 2019 Jun 9.