PMID- 3118700 OWN - NLM STAT- MEDLINE DCOM- 19871204 LR - 20190815 IS - 0272-6386 (Print) IS - 0272-6386 (Linking) VI - 10 IP - 5 DP - 1987 Nov TI - Profound hypophosphatemia in the course of acute renal failure. PG - 346-9 AB - Four of 19 patients with acute renal failure (ARF) requiring dialytic therapy were hypophosphatemic (serum phosphate, 0.8 +/- 0.8 mg/dL) during their illness. The hypophosphatemia could not be attributed to differences in the etiology of renal failure, frequency of dialysis, or residual renal function. No hypophosphatemic patient received phosphate-binding antacids. The hypophosphatemia was related to carbohydrate (CHO) providing a large percentage (greater than 79%) of total calories for a prolonged period. This complication was likely caused by tissue anabolism as well as by CHO-stimulated, insulin-induced intracellular shifts of phosphate. The greater use of parenteral fat as a caloric source and more aggressive phosphate supplementation despite the presence of ARF may help prevent this complication. FAU - Kurtin, P AU - Kurtin P AD - Department of Pediatrics, New England Medical Center, Boston, MA. FAU - Kouba, J AU - Kouba J LA - eng PT - Journal Article PL - United States TA - Am J Kidney Dis JT - American journal of kidney diseases : the official journal of the National Kidney Foundation JID - 8110075 RN - 0 (Dietary Carbohydrates) RN - 0 (Phosphates) SB - IM MH - Acute Kidney Injury/*blood/mortality/therapy MH - Adult MH - Aged MH - Dietary Carbohydrates/*administration & dosage MH - Energy Intake MH - Enteral Nutrition MH - Humans MH - Middle Aged MH - Parenteral Nutrition, Total/*adverse effects MH - Phosphates/administration & dosage/*blood MH - Renal Dialysis EDAT- 1987/11/01 00:00 MHDA- 1987/11/01 00:01 CRDT- 1987/11/01 00:00 PHST- 1987/11/01 00:00 [pubmed] PHST- 1987/11/01 00:01 [medline] PHST- 1987/11/01 00:00 [entrez] AID - S0272638687001161 [pii] AID - 10.1016/s0272-6386(87)80099-9 [doi] PST - ppublish SO - Am J Kidney Dis. 1987 Nov;10(5):346-9. doi: 10.1016/s0272-6386(87)80099-9.