PMID- 31195228
OWN - NLM
STAT- MEDLINE
DCOM- 20190827
LR  - 20190827
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 181
DP  - 2019 Oct 15
TI  - Are perfluoroalkyl substances in water and fish from drinking water source the 
      major pathways towards human health risk?
PG  - 194-201
LID - S0147-6513(19)30638-4 [pii]
LID - 10.1016/j.ecoenv.2019.06.010 [doi]
AB  - Due to potential adverse effects and bioaccumulation in biota and humans, 
      perfluoroalkyl substances (PFASs) have raised wide attention in recent years. 
      Ingestion is a vital pathway for PFASs to transmit to humans especially through 
      water and fish. In present study, PFASs in water and fish from the drinking water 
      source of Beijing in China were investigated. Three layers of water were 
      collected in order to find the connection between concentrations of PFASs and 
      depth of water, which showed no prominent correlation. PFASs in water from Miyun 
      Reservoir with concentrations of 5.30-8.50 ng/L, were relatively lower compared 
      with other reports on raw drinking water. Perfluorobutanoic acid (PFBA) and 
      perfluorooctanoic acid (PFOA) were the dominant PFASs. In addition, six species 
      of fish (including Cyprinus carpio, Carassius auratus, Erythroculter dabryi, 
      Pseudohemiculter dispar, Hypophthalmichthys molitrix and Siniperca chuatsi) were 
      analyzed, with concentrations of PFASs ranging from 1.70 to 14.32 ng/g wet weight 
      (w.w.). Due to relatively stronger bioaccumulation potential, long chain 
      perfluorinated carboxylates (PFCAs) and perfluorinated sulfonates (PFSAs) were 
      detected with higher concentrations, especially perfluoroundecanoic acid (PFUdA) 
      and perfluorodecanoic acid (PFDA). The estimated daily intake (EDI) of PFASs 
      through drinking water and fish consumption were 0.20-0.34 and 
      3.44-12.61 ng/kg bw/day based on Exposure Factors Handbook of Chinese Population, 
      respectively. In addition, the EDI of high-priority concern PFASs via pork, 
      chicken and dust were also calculated, with value of 0.015-0.043, 0.003-0.013 and 
      0.074-0.390 ng/kg bw/day, respectively. The total EDI of PFOS and PFOA via 
      diverse pathways were less than suggested tolerable daily intake (PFOS, 
      150 ng/kg bw/day; PFOA, 1500 ng/kg bw/day), indicating that the detected levels 
      would not cause severe health effects on Beijing residents.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Meng, Jing
AU  - Meng J
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; 
      University of Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Liu, Sifan
AU  - Liu S
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
FAU - Zhou, Yunqiao
AU  - Zhou Y
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; 
      University of Chinese Academy of Sciences, Beijing, 100049, China.
FAU - Wang, Tieyu
AU  - Wang T
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; 
      University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic 
      address: wangty@rcees.ac.cn.
LA  - eng
PT  - Journal Article
DEP - 20190610
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Alkanesulfonic Acids)
RN  - 0 (Caprylates)
RN  - 0 (Decanoic Acids)
RN  - 0 (Drinking Water)
RN  - 0 (Fatty Acids)
RN  - 0 (Fluorocarbons)
RN  - 0 (Water Pollutants, Chemical)
RN  - 0 (perfluoroundecanoic acid)
RN  - 335-76-2 (perfluorodecanoic acid)
RN  - 375-22-4 (perfluorobutyric acid)
RN  - 947VD76D3L (perfluorooctanoic acid)
SB  - IM
MH  - Adult
MH  - Alkanesulfonic Acids/analysis
MH  - Animals
MH  - Beijing
MH  - Caprylates/analysis
MH  - Carps/metabolism
MH  - Child
MH  - Decanoic Acids/analysis
MH  - Drinking Water/*chemistry
MH  - Environmental Exposure
MH  - Fatty Acids/analysis
MH  - Fishes/*metabolism
MH  - Fluorocarbons/*analysis/toxicity
MH  - Humans
MH  - Risk Assessment
MH  - *Seafood
MH  - Water Pollutants, Chemical/*analysis
OTO - NOTNLM
OT  - Drinking water source
OT  - Fish
OT  - Health risk
OT  - Human exposure
OT  - PFASs
EDAT- 2019/06/14 06:00
MHDA- 2019/08/28 06:00
CRDT- 2019/06/14 06:00
PHST- 2019/04/11 00:00 [received]
PHST- 2019/05/29 00:00 [revised]
PHST- 2019/06/03 00:00 [accepted]
PHST- 2019/06/14 06:00 [pubmed]
PHST- 2019/08/28 06:00 [medline]
PHST- 2019/06/14 06:00 [entrez]
AID - S0147-6513(19)30638-4 [pii]
AID - 10.1016/j.ecoenv.2019.06.010 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2019 Oct 15;181:194-201. doi: 
      10.1016/j.ecoenv.2019.06.010. Epub 2019 Jun 10.