PMID- 31196704
OWN - NLM
STAT- MEDLINE
DCOM- 20200127
LR  - 20200127
IS  - 2212-4411 (Electronic)
VI  - 128
IP  - 4
DP  - 2019 Oct
TI  - Impact of micro-computed tomography reconstruction protocols on bone 
      microarchitecture analysis.
PG  - 411-417
LID - S2212-4403(19)30489-4 [pii]
LID - 10.1016/j.oooo.2019.05.001 [doi]
AB  - OBJECTIVE: The aim of this study was to assess the influence of reconstruction 
      protocols of micro-computed tomography (micro-CT) images on analyses of bone 
      microarchitecture. STUDY DESIGN: Micro-CT images of the maxillae of 5 Wistar rats 
      were reconstructed with different protocols by varying the levels of the 
      following tools: smoothing filter (SF; 2-6); ring artifact correction (RAC; 
      5-15); and beam hardening correction (BHC; 15%-60%). A control protocol (P0; 
      without any correction tool) and a standard protocol (SP; according to the 
      manufacturer's recommendation: SF = 2; RAC = 5; BHC = 45%) were also obtained. 
      For each protocol, 8 bone microarchitecture parameters were calculated (bone 
      volume/total volume [BV/TV], bone surface/total volume [BS/TV], trabecular number 
      [Tb.N], trabecular thickness [Tb.Th], trabecular separation [Tb.Sp], degree of 
      anisotropy [DA], connectivity density [Conn.D], and total porosity [Po-tot]) by 
      using CTAn software. Test protocols were compared with the SP by using 1-way 
      analysis of variance and the Dunnet post hoc test (alpha = 0.05). RESULTS: An inverse 
      relationship was observed between BHC tool levels and all microarchitecture 
      parameters except BV/TV and Tb.Th. The combination of BHC and SF significantly 
      influenced all microarchitecture parameters except for DA, for which all 
      protocols were similar to the SP (P > .05). CONCLUSIONS: Calculation of bone 
      microarchitecture parameters is influenced by the applied levels of artifact 
      correction tools, mainly BHC and SF. It is necessary to standardize such tool 
      levels for correct data interpretation.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Nascimento, Eduarda Helena Leandro
AU  - Nascimento EHL
AD  - Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental 
      School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil. 
      Electronic address: eduarda.hln@gmail.com.
FAU - Gaeta-Araujo, Hugo
AU  - Gaeta-Araujo H
AD  - Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental 
      School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
FAU - Brasil, Danieli M
AU  - Brasil DM
AD  - Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental 
      School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
FAU - Madlum, Daniela Verardi
AU  - Madlum DV
AD  - Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental 
      School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
FAU - Freitas, Deborah Q
AU  - Freitas DQ
AD  - Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental 
      School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
FAU - Haiter-Neto, Frascisco
AU  - Haiter-Neto F
AD  - Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental 
      School, University of Campinas (UNICAMP), Piracicaba, Sao Paulo, Brazil.
FAU - Oliveira-Santos, Christiano
AU  - Oliveira-Santos C
AD  - Department of Stomatology, Public Health, Forensic Dentistry, Division of Oral 
      Radiology, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Sao 
      Paulo, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20190521
PL  - United States
TA  - Oral Surg Oral Med Oral Pathol Oral Radiol
JT  - Oral surgery, oral medicine, oral pathology and oral radiology
JID - 101576782
SB  - IM
MH  - Algorithms
MH  - Animals
MH  - *Artifacts
MH  - Bone Density
MH  - *Maxilla/diagnostic imaging
MH  - Rats
MH  - Rats, Wistar
MH  - *X-Ray Microtomography
EDAT- 2019/06/15 06:00
MHDA- 2020/01/28 06:00
CRDT- 2019/06/15 06:00
PHST- 2019/01/23 00:00 [received]
PHST- 2019/05/03 00:00 [revised]
PHST- 2019/05/13 00:00 [accepted]
PHST- 2019/06/15 06:00 [pubmed]
PHST- 2020/01/28 06:00 [medline]
PHST- 2019/06/15 06:00 [entrez]
AID - S2212-4403(19)30489-4 [pii]
AID - 10.1016/j.oooo.2019.05.001 [doi]
PST - ppublish
SO  - Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Oct;128(4):411-417. doi: 
      10.1016/j.oooo.2019.05.001. Epub 2019 May 21.