PMID- 31198072 OWN - NLM STAT- MEDLINE DCOM- 20191118 LR - 20191118 IS - 1502-3850 (Electronic) IS - 0001-6357 (Linking) VI - 77 IP - 8 DP - 2019 Nov TI - Evaluation and comparison of serum vitamin D and calcium levels in periodontally healthy, chronic gingivitis and chronic periodontitis in patients with and without diabetes mellitus - a cross-sectional study. PG - 592-599 LID - 10.1080/00016357.2019.1623910 [doi] AB - Objective: Limited data are available with respect to the relation of vitamin D and calcium with periodontal infections and type-2 diabetes mellitus (T2DM). The aim of this cross-sectional study was to evaluate the levels of vitamin D and calcium in serum of periodontally healthy, chronic gingivitis and chronic periodontitis patients with and without T2DM. Material and methods: The study evaluated 100 patients equally divided into five groups (Group I to Group V) according to the inclusion criteria. Clinical parameters and serum 25-hydroxyvitamin D level were assessed. Other laboratory investigations comprised of random blood sugar, glycated haemoglobin and serum calcium. Results: The probing pocket depth and clinical attachment loss were found to be greater in chronic periodontitis and chronic periodontitis with diabetes mellitus, while the vitamin D and calcium levels were found to be least in these groups. When vitamin D and calcium levels were compared between periodontal disease with diabetes to that of non-diabetics, statistically significant difference were found between the two with p-value of .001 indicating decrease in levels of vitamin D and calcium with increase in RBS and HbA1c values. Conclusion: Vitamin D and calcium levels are inversely correlated with random blood sugar and glycated haemoglobin and also probing pocket depth and clinical attachment loss, thus contributing towards increase in periodontal disease severity. FAU - Agrawal, Anshuka A AU - Agrawal AA AD - Department of Periodontics & Implantology, VSPM Dental College and Research Centre , Nagpur , India. FAU - Kolte, Abhay P AU - Kolte AP AD - Department of Periodontics & Implantology, VSPM Dental College and Research Centre , Nagpur , India. FAU - Kolte, Rajashri A AU - Kolte RA AD - Department of Periodontics & Implantology, VSPM Dental College and Research Centre , Nagpur , India. FAU - Chari, Suresh AU - Chari S AD - Department of Biochemistry, NKP Salve Institute of Medical Sciences , Nagpur , India. FAU - Gupta, Madhur AU - Gupta M AD - Department of Biochemistry, NKP Salve Institute of Medical Sciences , Nagpur , India. FAU - Pakhmode, Resham AU - Pakhmode R AD - Department of Periodontics & Implantology, VSPM Dental College and Research Centre , Nagpur , India. LA - eng PT - Journal Article DEP - 20190614 PL - Sweden TA - Acta Odontol Scand JT - Acta odontologica Scandinavica JID - 0370344 RN - 0 (Blood Glucose) RN - 1406-16-2 (Vitamin D) RN - SY7Q814VUP (Calcium) SB - IM MH - Blood Glucose/metabolism MH - Calcium/*blood MH - *Chronic Periodontitis/blood MH - Cross-Sectional Studies MH - Dental Plaque Index MH - *Diabetes Mellitus, Type 2/blood MH - *Gingivitis/blood MH - Humans MH - Periodontal Attachment Loss MH - Periodontal Index MH - Vitamin D/*blood OTO - NOTNLM OT - Calcium OT - gingivitis OT - periodontitis OT - vitamin D EDAT- 2019/06/15 06:00 MHDA- 2019/11/19 06:00 CRDT- 2019/06/15 06:00 PHST- 2019/06/15 06:00 [pubmed] PHST- 2019/11/19 06:00 [medline] PHST- 2019/06/15 06:00 [entrez] AID - 10.1080/00016357.2019.1623910 [doi] PST - ppublish SO - Acta Odontol Scand. 2019 Nov;77(8):592-599. doi: 10.1080/00016357.2019.1623910. Epub 2019 Jun 14.