PMID- 31198456
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1857-9655 (Print)
IS  - 1857-9655 (Electronic)
IS  - 1857-9655 (Linking)
VI  - 7
IP  - 9
DP  - 2019 May 15
TI  - Comparison between the Outcomes of Using Biodegradable-Polymer Drug-Eluting 
      Stents and Those of Using Durable-Polymer Drug-Eluting Stents in Acute Coronary 
      Syndrome Patients Undergoing Percutaneous Coronary Intervention.
PG  - 1466-1470
LID - 10.3889/oamjms.2019.345 [doi]
AB  - BACKGROUND: Many randomised control studies showed that percutaneous coronary 
      interventions using biodegradable-polymer drug-eluting stents (DES) offer a safe 
      and effective alternative to durable-polymer DES. However, not many studies have 
      discussed its use in the setting of acute coronary syndromes. AIM: We aim to 
      compare the biodegradable-polymer DES with durable-polymer DES when it comes to 
      reducing the incidence of non-ST elevation acute coronary syndrome (NSTEACS) 
      associated with adverse events. METHODS: We enrolled 205 patients presenting with 
      NSTEACS and a TIMI risk score >/= 3 in this study and divided them into two groups, 
      group A and group B. Biodegradable-polymer DESs were exclusively used in group A, 
      while durable-polymer DESs were used in group B. Major adverse events were 
      reported in both groups during the hospital stay and patients were followed-up 
      for 1 year. RESULTS: In our patients, we intervened on 390 diseased segments in a 
      total of 360 vessels. After intervention, TIMI 0 was achieved in 0.97%, TIMI 1 in 
      1.46%, TIMI 2 in 2.45%, and TIMI 3 in 95.12% of the treated segments (P-value= 
      0.677). We implanted 121 biodegradable-polymer DESs and 146 durable-polymer DESs. 
      Clinical success was achieved in 95.12% of our cases. We had 55 patients who 
      needed repeated coronary angiography within 1 year (15 patients treated with 
      biodegradable-polymer DES and 24 patients treated with durable-polymer DES). 
      Eighteen patients experienced angina pains (8 patients treated with 
      biodegradable-polymer DES and 10 patients treated with durable-polymer DES). Only 
      5 patients needed TLR (2 patients treated with biodegradable-polymer DES and 3 
      patients treated with durable -polymer DES) (P-value = 0.591), three of them had 
      a myocardial infarction with documented angiographic evidence of significant 
      in-stent restenosis (1 patient treated with biodegradable-polymer DES and 2 
      patients treated with durable-polymer DESs). CONCLUSION: Biodegradable-polymer 
      DES represents a comparable alternative to durable-polymer DES in the setting of 
      acute coronary syndromes.
FAU - Fawzy, Abd-Allah Y
AU  - Fawzy AY
AD  - Critical Care Medicine Department, Cairo University, Cairo, Egypt.
FAU - Kenawi, Mahmoud M
AU  - Kenawi MM
AD  - Critical Care Medicine Department, Cairo University, Cairo, Egypt.
FAU - Aziz, Ahmed Abd El
AU  - Aziz AAE
AD  - Critical Care Medicine Department, Cairo University, Cairo, Egypt.
FAU - Moharam, Ayman N
AU  - Moharam AN
AD  - Critical Care Medicine Department, Cairo University, Cairo, Egypt.
FAU - Attia, Ibrahim M
AU  - Attia IM
AD  - Critical Care Medicine Department, Cairo University, Cairo, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20190514
PL  - North Macedonia
TA  - Open Access Maced J Med Sci
JT  - Open access Macedonian journal of medical sciences
JID - 101662294
PMC - PMC6542403
OTO - NOTNLM
OT  - Acute Coronary Syndrome
OT  - Biodegradable-Polymer DES
OT  - Major Adverse Cardiac Events
OT  - Non-ST Segment Elevation
EDAT- 2019/06/15 06:00
MHDA- 2019/06/15 06:01
PMCR- 2019/05/14
CRDT- 2019/06/15 06:00
PHST- 2019/03/04 00:00 [received]
PHST- 2019/05/01 00:00 [revised]
PHST- 2019/05/02 00:00 [accepted]
PHST- 2019/06/15 06:00 [entrez]
PHST- 2019/06/15 06:00 [pubmed]
PHST- 2019/06/15 06:01 [medline]
PHST- 2019/05/14 00:00 [pmc-release]
AID - OAMJMS-7-1466 [pii]
AID - 10.3889/oamjms.2019.345 [doi]
PST - epublish
SO  - Open Access Maced J Med Sci. 2019 May 14;7(9):1466-1470. doi: 
      10.3889/oamjms.2019.345. eCollection 2019 May 15.