PMID- 31199320 OWN - NLM STAT- MEDLINE DCOM- 20200406 LR - 20200701 IS - 1438-8871 (Electronic) IS - 1439-4456 (Print) IS - 1438-8871 (Linking) VI - 21 IP - 6 DP - 2019 Jun 2 TI - Relationship Between Patient-Reported Outcome Measures and the Severity of Chronic Obstructive Pulmonary Disease in the Context of an Innovative Digitally Supported 24-Hour Service: Longitudinal Study. PG - e10924 LID - 10.2196/10924 [doi] LID - e10924 AB - BACKGROUND: Individuals with chronic obstructive pulmonary disease (COPD) live with the burden of a progressive life-threatening condition that is often accompanied by anxiety and depression. The severity of the condition is usually considered from a clinical perspective and characterized according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification of severity (1-4) and a risk assessment (A through D) that focuses on the patient's symptoms and number of exacerbations, but information about perceived health or ability to manage the condition are rarely included. OBJECTIVE: We evaluated 3 patient-reported outcome measurements (PROMs) to examine how these can be used to report on individuals with COPD who were supported by a digitally assisted intervention that aims to increase the patient's management of their condition to improve their well-being. METHODS: A total of 93 individuals with COPD were enrolled. At baseline and after 6 and 12 months, we measured self-reported self-management (Health Education Impact Questionnaire, heiQ) and health literacy (Health Literacy Questionnaire, HLQ), and physical and mental health (Short Form-36, SF-36) PROMs were collected. The scores of the 19 PROM dimensions were related to COPD severity, that is, GOLD risk assessment, pulmonary function at entry, and number of exacerbations of a period up to 12 months. The initial PROM scores were also compared with pulmonary function, exacerbations, and GOLD risk assessment to predict the number of contacts within the first 90 days. RESULTS: At baseline, 2 dimensions from heiQ and SF-36 Physical health differed significantly between GOLD risk factor groups, indicating more distress and poorer attitudes and health status with increasing severity (GOLD risk assessment). Pulmonary function (FEV1) was negatively associated with the severity of the condition. After 6 months, we observed an increase in heiQ6 (skill and technique acquisition) and a reduction in emotional distress. The latter effect persisted after 12 months, where heiQ4 (self-monitoring and insight) also increased. HLQ3 (actively managing my health) decreased after 6 and 12 months. The number of exacerbations and the GOLD risk factor assessment predicted the number of contacts during the first 90 days. Furthermore, 2 of the PROMS heiQ6 (skill and technique acquisition) and HLQ8 (ability to find good health information) evaluated at baseline were associated with the number of contacts within the first 90 after enrollment. The pulmonary function was not associated with the number of contacts. CONCLUSIONS: Our data suggest that selected dimensions from HLQ, heiQ, and SF-36 can be used as PROMs in relation to COPD to provide researchers and clinicians with greater insight into how this condition affects individuals' ability to understand and manage their condition and perception of their physical and mental health. The PROMs add to the information obtained with the clinical characteristics including the GOLD risk factor assessment. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/resprot.6506. CI - (c)Signe Lindskrog, Karl Bang Christensen, Richard H Osborne, Soren Vingtoft, Klaus Phanareth, Lars Kayser. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 02.06.2019. FAU - Lindskrog, Signe AU - Lindskrog S AUID- ORCID: 0000-0003-4662-7063 AD - Department of Public Health, University of Copenhagen, Copenhagen, Denmark. FAU - Christensen, Karl Bang AU - Christensen KB AUID- ORCID: 0000-0003-4518-5187 AD - Department of Public Health, University of Copenhagen, Copenhagen, Denmark. FAU - Osborne, Richard H AU - Osborne RH AUID- ORCID: 0000-0002-9081-2699 AD - Department of Public Health, University of Copenhagen, Copenhagen, Denmark. AD - Faculty of Health, Arts and Design, Swinburne University of Technology, Hawthorn, Australia. FAU - Vingtoft, Soren AU - Vingtoft S AUID- ORCID: 0000-0002-6999-1573 AD - Region Zeeland, Soro, Denmark. FAU - Phanareth, Klaus AU - Phanareth K AUID- ORCID: 0000-0003-4010-7083 AD - Region Zeeland, Soro, Denmark. FAU - Kayser, Lars AU - Kayser L AUID- ORCID: 0000-0002-0909-4088 AD - Department of Public Health, University of Copenhagen, Copenhagen, Denmark. LA - eng GR - P30 DK081943/DK/NIDDK NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190602 PL - Canada TA - J Med Internet Res JT - Journal of medical Internet research JID - 100959882 SB - IM MH - Aged MH - Aged, 80 and over MH - Female MH - Humans MH - Longitudinal Studies MH - Male MH - Middle Aged MH - *Patient Reported Outcome Measures MH - Pulmonary Disease, Chronic Obstructive/*diagnosis MH - Quality of Life/*psychology PMC - PMC6595940 OTO - NOTNLM OT - SF-36 OT - chronic obstructive pulmonary disease OT - empowerment OT - epital living lab OT - health education impact questionnaire OT - health literacy OT - health literacy questionnaire OT - patient reported outcome measures OT - self-reported mental and physical health COIS- Conflicts of Interest: None declared. EDAT- 2019/06/15 06:00 MHDA- 2020/04/09 06:00 PMCR- 2019/06/02 CRDT- 2019/06/15 06:00 PHST- 2018/05/02 00:00 [received] PHST- 2019/04/04 00:00 [accepted] PHST- 2019/02/27 00:00 [revised] PHST- 2019/06/15 06:00 [entrez] PHST- 2019/06/15 06:00 [pubmed] PHST- 2020/04/09 06:00 [medline] PHST- 2019/06/02 00:00 [pmc-release] AID - v21i6e10924 [pii] AID - 10.2196/10924 [doi] PST - epublish SO - J Med Internet Res. 2019 Jun 2;21(6):e10924. doi: 10.2196/10924.