PMID- 31208501
OWN - NLM
STAT- MEDLINE
DCOM- 20190711
LR  - 20200808
IS  - 1008-8830 (Print)
IS  - 1008-8830 (Linking)
VI  - 21
IP  - 6
DP  - 2019 Jun
TI  - [Value of absolute counts of lymphocyte subsets in the early prediction of 
      refractory Mycoplasma pneumoniae pneumonia in children].
PG  - 511-516
AB  - OBJECTIVE: To study the value of absolute counts of lymphocyte subsets in the 
      early prediction of refractory Mycoplasma pneumoniae pneumonia (RMPP) in 
      children. METHODS: A retrospective analysis was performed for the clinical data 
      of 244 children with Mycoplasma pneumoniae pneumonia (MPP). Among these children, 
      166 had MPP, and 58 had RMPP. The two groups were compared in terms of clinical 
      features and laboratory markers such as lymphocyte subsets, lactate 
      dehydrogenase, C-reactive protein, procalcitonin and immunoglobulin E (IgE). The 
      receiver operating characteristic (ROC) curve was used to evaluate the specific 
      indices for predicting RMMP. RESULTS: There were significant differences between 
      the two groups in the absolute counts of CD3(+), CD4(+), CD19(+), and CD56(+) 
      lymphocytes and the serum levels of lactate dehydrogenase, C-reactive protein, 
      and IgE (P<0.05). The ROC curve analysis showed that the absolute counts of 
      CD3(+), CD4(+) and CD19(+) lymphocytes had an area under the ROC curve (AUC) of 
      0.866, 0.900 and 0.842 respectively in the differential diagnosis of RMPP and 
      MPP, with a sensitivity of 86%, 90% and 82% respectively and a specificity of 
      75%, 70% and 80% respectively. CONCLUSIONS: The absolute counts of CD3(+), CD4(+) 
      and CD19(+) lymphocytes can be used to predict RMPP in children.
FAU - Li, Na
AU  - Li N
AD  - Department of Pediatric Neurology & Rehabilitation Medicine, Shenyang Children's 
      Hospital, Shenyang 110032, China. 706502446@qq.com.
FAU - Mu, Ya-Ping
AU  - Mu YP
FAU - Chen, Jing
AU  - Chen J
FAU - Li, Bin
AU  - Li B
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhongguo Dang Dai Er Ke Za Zhi
JT  - Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
JID - 100909956
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - C-Reactive Protein
MH  - Child
MH  - Humans
MH  - *Lymphocyte Subsets
MH  - *Mycoplasma pneumoniae
MH  - *Pneumonia, Mycoplasma
MH  - Retrospective Studies
PMC - PMC7389588
EDAT- 2019/06/19 06:00
MHDA- 2019/07/12 06:00
PMCR- 2019/06/25
CRDT- 2019/06/19 06:00
PHST- 2019/06/19 06:00 [entrez]
PHST- 2019/06/19 06:00 [pubmed]
PHST- 2019/07/12 06:00 [medline]
PHST- 2019/06/25 00:00 [pmc-release]
AID - 10.7499/j.issn.1008-8830.2019.06.003 [pii]
AID - zgddekzz-21-6-511 [pii]
AID - 10.7499/j.issn.1008-8830.2019.06.003 [doi]
PST - ppublish
SO  - Zhongguo Dang Dai Er Ke Za Zhi. 2019 Jun;21(6):511-516. doi: 
      10.7499/j.issn.1008-8830.2019.06.003.