PMID- 31211289 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 2632-010X (Electronic) IS - 2632-010X (Linking) VI - 12 DP - 2019 Jan-Dec TI - Primary Hepatic Follicular Lymphoma Presenting as Sub-acute Liver Failure: A Case Report and Review of the Literature. PG - 2632010X19829261 LID - 10.1177/2632010X19829261 [doi] LID - 2632010X19829261 AB - Sub-acute liver failure is a term that describes the relatively sudden loss of liver function, usually >21 days and <26 weeks, with impaired synthetic function and associated encephalopathy in a person with no pre-existing liver disease or cirrhosis. It is commonly caused by viruses and drugs, less so by malignancy. Our patient is a 71-year-old Japanese man who presented with signs of sub-acute liver failure. A subsequent liver biopsy demonstrated involvement by B-cell non-Hodgkin lymphoma. Evaluation of the bone marrow demonstrated significant marrow involvement by B-cell lymphoma. The fluorescence in situ hybridization (FISH) returned positive for t(14; 18). Noted was the patient's clinical presentation of cholestasis secondary to hepatic lymphoma with no evidence of lymphadenopathy or peripheralized lymphoma. Given the disease distribution, the overall findings are consistent with primary hepatic follicular lymphoma as described in few case reports and small case series in the literature. FAU - Williams, Mary-Jane Ou AU - Williams MO AD - Internal Medicine Residency Program, MountainView Hospital, Las Vegas, NV, USA. FAU - Akhondi, Hossein AU - Akhondi H AD - Internal Medicine Residency Program, MountainView Hospital, Las Vegas, NV, USA. FAU - Khan, Omar AU - Khan O AD - Department of Pathology, MountainView Hospital and Aurora Diagnostics LMC Pathology Services, Las Vegas, NV, USA. LA - eng PT - Journal Article DEP - 20190212 PL - United States TA - Clin Pathol JT - Clinical pathology (Thousand Oaks, Ventura County, Calif.) JID - 101741182 PMC - PMC6546941 OTO - NOTNLM OT - Sub-acute liver failure OT - follicular lymphoma OT - primary hepatic lymphoma COIS- Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2019/06/19 06:00 MHDA- 2019/06/19 06:01 PMCR- 2019/02/12 CRDT- 2019/06/19 06:00 PHST- 2018/12/02 00:00 [received] PHST- 2018/12/09 00:00 [accepted] PHST- 2019/06/19 06:00 [entrez] PHST- 2019/06/19 06:00 [pubmed] PHST- 2019/06/19 06:01 [medline] PHST- 2019/02/12 00:00 [pmc-release] AID - 10.1177_2632010X19829261 [pii] AID - 10.1177/2632010X19829261 [doi] PST - epublish SO - Clin Pathol. 2019 Feb 12;12:2632010X19829261. doi: 10.1177/2632010X19829261. eCollection 2019 Jan-Dec.