PMID- 31216699
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 2076-3425 (Print)
IS  - 2076-3425 (Electronic)
IS  - 2076-3425 (Linking)
VI  - 9
IP  - 6
DP  - 2019 Jun 18
TI  - Imagery-Mediated Verbal Learning Depends on Vividness-Familiarity Interactions: 
      The Possible Role of Dualistic Resting State Network Activity Interference.
LID - 10.3390/brainsci9060143 [doi]
LID - 143
AB  - Using secondary database analysis, we tested whether the (implicit) familiarity 
      of eliciting noun-cues and the (explicit) vividness of corresponding imagery 
      exerted additive or interactive influences on verbal learning, as measured by the 
      probability of incidental noun recall and image latency times (RTs). Noun-cues 
      with incongruent levels of vividness and familiarity (high/low; low/high, 
      respectively) at encoding were subsequently associated at retrieval with the 
      lowest recall probabilities, while noun-cues related with congruent levels 
      (high/high; low/low) were associated with higher recall probabilities. RTs in the 
      high vividness and high familiarity grouping were significantly faster than all 
      other subsets (low/low, low/high, high/low) which did not significantly differ 
      among each other. The findings contradict: (1) associative theories predicting 
      positive monotonic relationships between memory strength and learning; and (2) 
      non-monotonic plasticity hypothesis (NMPH), aiming at generalizing the 
      non-monotonic relationship between a neuron's excitation level and its synaptic 
      strength to broad neural networks. We propose a dualistic neuropsychological 
      model of memory consolidation that mimics the global activity in two large 
      resting-state networks (RSNs), the default mode network (DMN) and the 
      task-positive-network (TPN). Based on this model, we suggest that incongruence 
      and congruence between vividness and familiarity reflect, respectively, 
      competition and synergy between DMN and TPN activity. We argue that competition 
      or synergy between these RSNs at the time of stimulus encoding disproportionately 
      influences long term semantic memory consolidation in healthy controls. These 
      findings could assist in developing neurophenomenological markers of core memory 
      deficits currently hypothesized to be shared across multiple psychopathological 
      conditions.
FAU - Lefebvre, Etienne
AU  - Lefebvre E
AD  - Neuroscience of Imagination Cognition and Emotion Research (NICER) Lab, 
      Neuroscience Department, Carleton University, Ottawa, ON K1S 5B6, Canada. 
      EtienneLefebvre@cmail.carleton.ca.
FAU - D'Angiulli, Amedeo
AU  - D'Angiulli A
AUID- ORCID: 0000-0002-8295-9850
AD  - Neuroscience of Imagination Cognition and Emotion Research (NICER) Lab, 
      Neuroscience Department, Carleton University, Ottawa, ON K1S 5B6, Canada. 
      amedeo.dangiulli@carleton.ca.
LA  - eng
GR  - standard research grant/Social Sciences and Humanities Research Council of 
      Canada/
PT  - Journal Article
DEP - 20190618
PL  - Switzerland
TA  - Brain Sci
JT  - Brain sciences
JID - 101598646
PMC - PMC6627679
OTO - NOTNLM
OT  - DMN
OT  - TPN
OT  - familiarity
OT  - memory
OT  - mental imagery
OT  - vividness
COIS- The authors report no conflict of interest regarding the publication of this 
      paper.
EDAT- 2019/06/21 06:00
MHDA- 2019/06/21 06:01
PMCR- 2019/06/01
CRDT- 2019/06/21 06:00
PHST- 2019/05/02 00:00 [received]
PHST- 2019/06/16 00:00 [revised]
PHST- 2019/06/17 00:00 [accepted]
PHST- 2019/06/21 06:00 [entrez]
PHST- 2019/06/21 06:00 [pubmed]
PHST- 2019/06/21 06:01 [medline]
PHST- 2019/06/01 00:00 [pmc-release]
AID - brainsci9060143 [pii]
AID - brainsci-09-00143 [pii]
AID - 10.3390/brainsci9060143 [doi]
PST - epublish
SO  - Brain Sci. 2019 Jun 18;9(6):143. doi: 10.3390/brainsci9060143.