PMID- 31219356
OWN - NLM
STAT- MEDLINE
DCOM- 20200612
LR  - 20200612
IS  - 1747-4094 (Electronic)
IS  - 1747-4094 (Linking)
VI  - 12
IP  - 9
DP  - 2019 Sep
TI  - Bariatric venous thromboembolism prophylaxis: an update on the literature.
PG  - 763-771
LID - 10.1080/17474086.2019.1634542 [doi]
AB  - Introduction: Rates of obesity have been increasing worldwide and with the 
      current situation obesity now represents an epidemic. Bariatric surgery is one 
      the most effective ways to help reduce weight and sustain weight loss. Venous 
      thromboembolism is a major cause of morbidity and mortality among bariatric 
      surgery patients with no clearly established guidelines on prophylaxis. Areas 
      covered: In this review the authors summarize clinical studies evaluating 
      unfractionated heparin (UFH) and low molecular weight heparins (LMWH) in 
      bariatric surgery patients. The authors present studies that assessed venous 
      thromboembolic (VTE)-related risk stratification but also various dosing regimens 
      of heparin products in this population of patients. Moreover, the authors will 
      also present the feasibility of using direct oral anticoagulants (DOACs) for 
      venous thromboembolism (VTE) prevention along with providing a summary of few 
      current guidelines for VTE prevention in bariatric surgery patients. Expert 
      opinion: Based on the data presented in this review, the authors conclude that 
      LMWHs may be better options than UFH for VTE prophylaxis in bariatric surgery 
      patients. We also conclude that risk stratifying bariatric patients may be a 
      better approach when deciding on the best thromboprophylaxis modality, dose and 
      duration.
FAU - Hamadi, Rachelle
AU  - Hamadi R
AD  - Department of Internal Medicine, American University of Beirut Medical Center , 
      Beirut , Lebanon.
FAU - Marlow, Christina F
AU  - Marlow CF
AD  - Department of Internal Medicine, George Washington University School of Medicine 
      , Washington , D.C. , USA.
FAU - Nassereddine, Samah
AU  - Nassereddine S
AD  - Department of Internal Medicine, George Washington University School of Medicine 
      , Washington , D.C. , USA.
FAU - Taher, Ali
AU  - Taher A
AD  - Department of Internal Medicine, American University of Beirut Medical Center , 
      Beirut , Lebanon.
FAU - Finianos, Antoine
AU  - Finianos A
AD  - Department of Internal Medicine, American University of Beirut Medical Center , 
      Beirut , Lebanon.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190805
PL  - England
TA  - Expert Rev Hematol
JT  - Expert review of hematology
JID - 101485942
RN  - 0 (Anticoagulants)
RN  - 0 (Factor Xa Inhibitors)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Anticoagulants/administration & dosage/*therapeutic use
MH  - *Bariatric Surgery/adverse effects
MH  - Bariatrics
MH  - Factor Xa Inhibitors/administration & dosage/therapeutic use
MH  - Heparin/administration & dosage/*therapeutic use
MH  - Heparin, Low-Molecular-Weight/administration & dosage/*therapeutic use
MH  - Humans
MH  - Venous Thromboembolism/etiology/*prevention & control
OTO - NOTNLM
OT  - Anti-Xa
OT  - bariatric surgery
OT  - direct oral anticoagulants
OT  - low molecular weight heparin
OT  - prophylaxis. venous thromboembolism
EDAT- 2019/06/21 06:00
MHDA- 2020/06/13 06:00
CRDT- 2019/06/21 06:00
PHST- 2019/06/21 06:00 [pubmed]
PHST- 2020/06/13 06:00 [medline]
PHST- 2019/06/21 06:00 [entrez]
AID - 10.1080/17474086.2019.1634542 [doi]
PST - ppublish
SO  - Expert Rev Hematol. 2019 Sep;12(9):763-771. doi: 10.1080/17474086.2019.1634542. 
      Epub 2019 Aug 5.