PMID- 31221698
OWN - NLM
STAT- MEDLINE
DCOM- 20200320
LR  - 20200701
IS  - 1935-5548 (Electronic)
IS  - 0149-5992 (Print)
IS  - 0149-5992 (Linking)
VI  - 42
IP  - 7
DP  - 2019 Jul
TI  - Aerobic Fitness and Adherence to Guideline-Recommended Minimum Physical Activity 
      Among Ambulatory Patients With Type 2 Diabetes Mellitus.
PG  - 1333-1339
LID - 10.2337/dc18-2634 [doi]
AB  - OBJECTIVE: Lifestyle intervention remains the cornerstone of management of type 2 
      diabetes mellitus (T2DM). However, adherence to physical activity (PA) 
      recommendations and the impact of that adherence on cardiorespiratory fitness in 
      this population have been poorly described. We sought to investigate adherence to 
      PA recommendations and its association with cardiorespiratory fitness in a 
      population of patients with T2DM. RESEARCH DESIGN AND METHODS: A cross-sectional 
      analysis of baseline data from a randomized clinical trial (NCT00424762) was 
      performed. A total of 150 individuals with medically treated T2DM and 
      atherosclerotic cardiovascular disease (ASCVD) or risk factors for ASCVD were 
      recruited from outpatient clinics at a single academic medical center. All 
      individuals underwent a graded maximal exercise treadmill test to exhaustion with 
      breath-by-breath gas exchange analysis to determine VO(2peak). PA was estimated 
      using a structured 7-Day Physical Activity Recall interview. RESULTS: 
      Participants had a mean +/- SD age of 54.9 +/- 9.0 years; 41% were women, 40% were 
      black, and 21% were Hispanic. The mean HbA(1c) was 7.7 +/- 1.8% and the mean BMI, 
      34.5 +/- 7.2 kg/m(2). A total of 72% had hypertension, 73% had hyperlipidemia, and 
      35% had prevalent ASCVD. The mean +/- SD reported daily PA was 34.3 +/- 4 kcal/kg, 
      only 7% above a sedentary state; 47% of the cohort failed to achieve the minimum 
      recommended PA. Mean +/- SD VO(2peak) was 27.4 +/- 6.5 mL/kg fat-free mass/min (18.8 
      +/- 5.0 mL/kg/min). CONCLUSIONS: On average, patients with T2DM who have or are at 
      risk for ASCVD report low levels of PA and have low measured cardiopulmonary 
      fitness. This underscores the importance of continued efforts to close this 
      therapeutic gap.
CI  - (c) 2019 by the American Diabetes Association.
FAU - Jarvie, Jennifer L
AU  - Jarvie JL
AD  - Division of Cardiology, University of Colorado School of Medicine, Aurora, CO.
FAU - Pandey, Ambarish
AU  - Pandey A
AD  - Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, 
      TX.
FAU - Ayers, Colby R
AU  - Ayers CR
AD  - Department of Clinical Sciences, University of Texas Southwestern Medical Center, 
      Dallas, TX.
FAU - McGavock, Jonathan M
AU  - McGavock JM
AD  - Manitoba Institute of Child Health, Winnipeg, Manitoba, Canada.
FAU - Senechal, Martin
AU  - Senechal M
AD  - Cardio-Metabolic Exercise and Lifestyle Laboratory, Fredericton, New Brunswick, 
      Canada.
AD  - Faculty of Kinesiology, University of New Brunswick, Fredericton, New Brunswick, 
      Canada.
FAU - Berry, Jarett D
AU  - Berry JD
AD  - Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, 
      TX.
FAU - Patel, Kershaw V
AU  - Patel KV
AD  - Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, 
      TX.
FAU - McGuire, Darren K
AU  - McGuire DK
AUID- ORCID: 0000-0002-6412-7989
AD  - Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, 
      TX darren.mcguire@utsouthwestern.edu.
AD  - Department of Clinical Sciences, University of Texas Southwestern Medical Center, 
      Dallas, TX.
LA  - eng
SI  - ClinicalTrials.gov/NCT00424762
GR  - K23 HL092229/HL/NHLBI NIH HHS/United States
GR  - M01 RR000633/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20190521
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
RN  - 05V02F2KDG (Rosiglitazone)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Ambulatory Care/statistics & numerical data
MH  - Atherosclerosis/complications/drug therapy/physiopathology
MH  - Cardiorespiratory Fitness/*physiology
MH  - Cardiovascular System/drug effects/physiopathology
MH  - Combined Modality Therapy
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*epidemiology/*physiopathology/therapy
MH  - Diabetic Angiopathies/drug therapy/epidemiology/physiopathology
MH  - Exercise/*physiology
MH  - Exercise Test
MH  - Female
MH  - Guideline Adherence/statistics & numerical data
MH  - Humans
MH  - Life Style
MH  - Male
MH  - Middle Aged
MH  - Patient Compliance/*statistics & numerical data
MH  - Physical Fitness/physiology
MH  - Risk Factors
MH  - Rosiglitazone/therapeutic use
PMC - PMC6609956
EDAT- 2019/06/22 06:00
MHDA- 2020/03/21 06:00
PMCR- 2020/07/01
CRDT- 2019/06/22 06:00
PHST- 2018/12/26 00:00 [received]
PHST- 2019/04/19 00:00 [accepted]
PHST- 2019/06/22 06:00 [entrez]
PHST- 2019/06/22 06:00 [pubmed]
PHST- 2020/03/21 06:00 [medline]
PHST- 2020/07/01 00:00 [pmc-release]
AID - dc18-2634 [pii]
AID - 2634 [pii]
AID - 10.2337/dc18-2634 [doi]
PST - ppublish
SO  - Diabetes Care. 2019 Jul;42(7):1333-1339. doi: 10.2337/dc18-2634. Epub 2019 May 
      21.