PMID- 3122555 OWN - NLM STAT- MEDLINE DCOM- 19880210 LR - 20190510 IS - 0002-9173 (Print) IS - 0002-9173 (Linking) VI - 89 IP - 1 DP - 1988 Jan TI - Use of "average of normals" quality control procedure in the detection and resolution of assay discrepancies. PG - 125-9 AB - Improved computer technology and imperatives for cost control have made the use of "average of normals" (AVON) procedure an attractive alternative to the more expensive standard quality control programs for clinical laboratory assay monitoring. The authors report the use of a version of the AVON procedure to resolve assay discrepancies with CO2 determination that the traditional quality control program appeared incapable of detecting. Their study suggests that the mean of patients within the reference interval (RI) is a sensitive indicator of accuracy, whereas the percentage of patients within RI is a good indicator of random imprecision. FAU - Woo, J AU - Woo J AD - Division of Clinical Pathology, State University of New York Health Science Center, Syracuse 13210. FAU - LeFever, D AU - LeFever D FAU - Winkelman, J W AU - Winkelman JW LA - eng PT - Journal Article PL - England TA - Am J Clin Pathol JT - American journal of clinical pathology JID - 0370470 RN - 142M471B3J (Carbon Dioxide) SB - IM MH - Carbon Dioxide/blood MH - Chemistry, Clinical/*methods MH - Numerical Analysis, Computer-Assisted MH - Quality Control MH - Statistics as Topic EDAT- 1988/01/01 00:00 MHDA- 1988/01/01 00:01 CRDT- 1988/01/01 00:00 PHST- 1988/01/01 00:00 [pubmed] PHST- 1988/01/01 00:01 [medline] PHST- 1988/01/01 00:00 [entrez] AID - 10.1093/ajcp/89.1.125 [doi] PST - ppublish SO - Am J Clin Pathol. 1988 Jan;89(1):125-9. doi: 10.1093/ajcp/89.1.125.