PMID- 31228026
OWN - NLM
STAT- MEDLINE
DCOM- 20191118
LR  - 20231014
IS  - 1573-3254 (Electronic)
IS  - 1090-7165 (Print)
IS  - 1090-7165 (Linking)
VI  - 23
IP  - 9
DP  - 2019 Sep
TI  - Self-Reported Long-Term Antiretroviral Adherence: A Longitudinal Study Among HIV 
      Infected Pregnant Women in Mpumalanga, South Africa.
PG  - 2576-2587
LID - 10.1007/s10461-019-02563-z [doi]
AB  - We evaluate the impact of a multi-session cognitive behavioral prevention of 
      mother to child transmission (PMTCT) intervention on antiretroviral therapy (ART) 
      adherence. A total of 683 women were enrolled into a randomized control trial 
      conducted at twelve community health centres (CHCs) in Mpumalanga Province. 
      Participants were randomized to Standard Care or Enhanced PMTCT Intervention 
      (EI). EI received three group and three individual intervention sessions. EI 
      impact was ascertained on ART adherence (baseline vs 12 months post-partum). 
      Women in the intervention groups were less likely to remain stable with regards 
      to ART adherence over time compared to the control groups. In predicting if women 
      become adherent over time, the intervention condition had no impact. However, the 
      intervention condition was significantly positively associated with change to 
      non-adherence. The enhanced cognitive-behavioral PMTCT intervention did not show 
      any improvement in relation to maternal ART adherence relative to standard PMTCT 
      care.Trial registration Clinicaltrials.gov: number NCT02085356.
FAU - Ramlagan, Shandir
AU  - Ramlagan S
AUID- ORCID: 0000-0001-9906-4474
AD  - Social Aspects of Public Health, Human Sciences Research Council, Private Bag 
      X41, Pretoria, 0001, South Africa. sramlagan@hsrc.ac.za.
AD  - Department of Work & Social Psychology, Maastricht University, P.O. Box 616, 6200 
      MD, Maastricht, The Netherlands. sramlagan@hsrc.ac.za.
FAU - Rodriguez, Violeta J
AU  - Rodriguez VJ
AD  - Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, 
      University of Miami, 1400 NW 10th Ave, Miami, FL, 33136, USA.
AD  - Department of Psychology, University of Georgia, Athens, GA, 30605, USA.
FAU - Peltzer, Karl
AU  - Peltzer K
AD  - Social Aspects of Public Health, Human Sciences Research Council, Private Bag 
      X41, Pretoria, 0001, South Africa.
AD  - Department of Research and Innovation, University of Limpopo, Sovenga, 0727, 
      South Africa.
FAU - Ruiter, Robert A C
AU  - Ruiter RAC
AD  - Department of Work & Social Psychology, Maastricht University, P.O. Box 616, 6200 
      MD, Maastricht, The Netherlands.
FAU - Jones, Deborah L
AU  - Jones DL
AD  - Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, 
      University of Miami, 1400 NW 10th Ave, Miami, FL, 33136, USA.
FAU - Sifunda, Sibusiso
AU  - Sifunda S
AD  - Social Aspects of Public Health, Human Sciences Research Council, Private Bag 
      X41, Pretoria, 0001, South Africa.
AD  - Department of Work & Social Psychology, Maastricht University, P.O. Box 616, 6200 
      MD, Maastricht, The Netherlands.
LA  - eng
SI  - ClinicalTrials.gov/NCT02085356
GR  - R01 HD078187/HD/NICHD NIH HHS/United States
GR  - R01HD078187/NH/NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - AIDS Behav
JT  - AIDS and behavior
JID - 9712133
RN  - 0 (Anti-HIV Agents)
RN  - 0 (Anti-Retroviral Agents)
SB  - IM
MH  - Adult
MH  - Anti-HIV Agents/*therapeutic use
MH  - Anti-Retroviral Agents/therapeutic use
MH  - Antiretroviral Therapy, Highly Active
MH  - *Cognitive Behavioral Therapy
MH  - Female
MH  - HIV Infections/*drug therapy/epidemiology/psychology
MH  - Humans
MH  - Infectious Disease Transmission, Vertical/*prevention & control
MH  - Longitudinal Studies
MH  - Medication Adherence/ethnology/*psychology
MH  - Outcome and Process Assessment, Health Care
MH  - Postpartum Period
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*drug therapy/ethnology/psychology
MH  - Pregnant Women/ethnology/psychology
MH  - Self Report
MH  - South Africa/epidemiology
PMC - PMC6766468
OTO - NOTNLM
OT  - ART adherence
OT  - Maternal
OT  - Pregnancy
OT  - Randomized Control Trial
OT  - South Africa
COIS- The authors declare that they have no competing interests. The funding sponsors 
      had no role in the design of the study; in the collection, analyses, nor 
      interpretation of data; in the writing of the manuscript; nor the decision to 
      publish the results.
EDAT- 2019/06/23 06:00
MHDA- 2019/11/19 06:00
PMCR- 2019/06/21
CRDT- 2019/06/23 06:00
PHST- 2019/06/23 06:00 [pubmed]
PHST- 2019/11/19 06:00 [medline]
PHST- 2019/06/23 06:00 [entrez]
PHST- 2019/06/21 00:00 [pmc-release]
AID - 10.1007/s10461-019-02563-z [pii]
AID - 2563 [pii]
AID - 10.1007/s10461-019-02563-z [doi]
PST - ppublish
SO  - AIDS Behav. 2019 Sep;23(9):2576-2587. doi: 10.1007/s10461-019-02563-z.