PMID- 31228180 OWN - NLM STAT- MEDLINE DCOM- 20200129 LR - 20200225 IS - 2291-5222 (Print) IS - 2291-5222 (Electronic) IS - 2291-5222 (Linking) VI - 7 IP - 6 DP - 2019 Jun 21 TI - Mobile Health Management Platform-Based Pulmonary Rehabilitation for Patients With Non-Small Cell Lung Cancer: Prospective Clinical Trial. PG - e12645 LID - 10.2196/12645 [doi] LID - e12645 AB - BACKGROUND: Lung cancer patients experience various symptoms during treatment. Although pulmonary rehabilitation is an effective way to improve these symptoms, a medical environment of limited availability makes it difficult to provide seamless and adequate rehabilitation for lung cancer patients. OBJECTIVE: This study aimed to investigate the effects of a personalized pulmonary rehabilitation program using real-time mobile patient health data for patients with non-small cell lung cancer. METHODS: We conducted a prospective clinical trial in 64 patients with non-small cell lung cancer aged between 20 and 80 years at a large tertiary hospital in Seoul, South Korea. A 12-week personalized pulmonary rehabilitation program, called efil breath, was administered to determine the effectiveness of the newly developed rehabilitation app. Participants were randomly allocated to the fixed exercise or fixed-interactive exercise group (which received the personalized program). We measured changes in 6-minute walk distance (6MWD) and dyspnea (modified Medical Research Council [mMRC] score) at 6 weeks; and quality of life and service satisfaction at 12 weeks. We used the paired t test to analyze the variables. RESULTS: Patients used the newly developed mobile health pulmonary rehabilitation app and a real-time patient monitoring website. In all participants, significant changes were observed in 6MWD at 12 weeks from a mean of 433.43m (SD 65.60) to 471.25m (SD 75.69; P=.001), and mMRC from a mean score of 0.94 (0.66) to 0.61 (SD 0.82; P=.02). The intervention significantly improved their quality of life (EuroQol-visual analog scale [EQ-VAS]) compared with baseline (mean score 76.05, SD 12.37 vs 82.09, SD 13.67, respectively; P=.002). CONCLUSIONS: A personalized mobile health-based pulmonary rehabilitation app for recording and monitoring real-time health data of patients with non-small cell lung cancer can supplement traditional health care center-based rehabilitation programs. This technology can encourage improvement of physical activity, dyspnea, and quality of life. CI - (c)Wonjun Ji, Hee Kwon, Sungin Lee, Seulgi Kim, Jeong Sook Hong, Yu Rang Park, Hyeong Ryul Kim, Jae Cheol Lee, Eun Ji Jung, Donghyun Kim, Chang-Min Choi. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 21.06.2019. FAU - Ji, Wonjun AU - Ji W AUID- ORCID: 0000-0001-7164-2770 AD - Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. FAU - Kwon, Hee AU - Kwon H AUID- ORCID: 0000-0001-9910-1888 AD - LifeSemantics, Seoul, Republic of Korea. FAU - Lee, Sungin AU - Lee S AUID- ORCID: 0000-0002-4260-2160 AD - LifeSemantics, Seoul, Republic of Korea. FAU - Kim, Seulgi AU - Kim S AUID- ORCID: 0000-0001-5002-3313 AD - Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. FAU - Hong, Jeong Sook AU - Hong JS AUID- ORCID: 0000-0001-8260-5457 AD - Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. FAU - Park, Yu Rang AU - Park YR AUID- ORCID: 0000-0002-4210-2094 AD - Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Kim, Hyeong Ryul AU - Kim HR AUID- ORCID: 0000-0002-6691-7693 AD - Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Lee, Jae Cheol AU - Lee JC AUID- ORCID: 0000-0001-5963-0259 AD - Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. FAU - Jung, Eun Ji AU - Jung EJ AUID- ORCID: 0000-0002-9987-0529 AD - LifeSemantics, Seoul, Republic of Korea. FAU - Kim, Donghyun AU - Kim D AUID- ORCID: 0000-0003-0841-3830 AD - LifeSemantics, Seoul, Republic of Korea. FAU - Choi, Chang-Min AU - Choi CM AUID- ORCID: 0000-0002-2881-4669 AD - Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. AD - Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190621 PL - Canada TA - JMIR Mhealth Uhealth JT - JMIR mHealth and uHealth JID - 101624439 SB - IM MH - Adult MH - Aged MH - Carcinoma, Non-Small-Cell Lung/*rehabilitation MH - Exercise/psychology MH - Female MH - Humans MH - Lung/physiopathology MH - Male MH - Middle Aged MH - Prospective Studies MH - Rehabilitation/*instrumentation/methods MH - Self-Management/methods/psychology/statistics & numerical data MH - Seoul MH - Telemedicine/instrumentation/standards/statistics & numerical data PMC - PMC6611149 OTO - NOTNLM OT - carcinoma, non-small-cell lung OT - lung cancer OT - mHealth OT - pulmonary rehabilitation OT - telemedicine OT - telerehabilitation COIS- Conflicts of Interest: None declared. EDAT- 2019/06/23 06:00 MHDA- 2019/06/23 06:01 PMCR- 2019/06/21 CRDT- 2019/06/23 06:00 PHST- 2018/10/30 00:00 [received] PHST- 2019/05/05 00:00 [accepted] PHST- 2019/03/30 00:00 [revised] PHST- 2019/06/23 06:00 [entrez] PHST- 2019/06/23 06:00 [pubmed] PHST- 2019/06/23 06:01 [medline] PHST- 2019/06/21 00:00 [pmc-release] AID - v7i6e12645 [pii] AID - 10.2196/12645 [doi] PST - epublish SO - JMIR Mhealth Uhealth. 2019 Jun 21;7(6):e12645. doi: 10.2196/12645.