PMID- 31233375
OWN - NLM
STAT- MEDLINE
DCOM- 20200710
LR  - 20200710
IS  - 1568-5624 (Electronic)
IS  - 0920-5063 (Linking)
VI  - 30
IP  - 15
DP  - 2019 Oct
TI  - Biological properties of electrospun cellulose scaffolds from biomass.
PG  - 1399-1414
LID - 10.1080/09205063.2019.1636351 [doi]
AB  - Nowadays the development of sustainable technologies for the effective production 
      of polymeric materials that can be used as biomaterials will be of importance. In 
      this work, cellulose (CEL) was purified from potato peel waste (PPW) and used to 
      produce electrospun nanofibers for tissue engineering applications. The purified 
      CEL was solubilized in copper ethylenediamine (Cuen) and the electrospun 
      nanofibers was produced through electrospinning technique in diameter range of 
      250-500 nm at electrical field strength of 20 kV. To confirm the applicability of 
      the electrospun CEL scaffolds in tissue engineering, in vitro BALB-3T3 
      fibroblastic cell adhesion and cell proliferation tests were employed in this 
      study. Cell viability was evaluated by staining with ethidium bromide (EtBr) and 
      acridine orange (AO) to evaluate the possible effects of cytotoxicity of the CNF 
      scaffolds. Fluorescence studies confirmed that BALB-3T3 viable cells attached and 
      spread throughout the CEL scaffold. The attachment and spreading of viable cells 
      suggests that electrospun CEL scaffolds support growth of BALB-3T3 fibroblasts 
      cells and suggests that PPW can be a useful source of raw material for the 
      production of scaffolds for tissue engineering.
FAU - Friend, Debora Ferreira Laurito
AU  - Friend DFL
AD  - a Post Graduate Program in Materials for Engineering, Federal University of 
      Itajuba (UNIFEI) , Itajuba-MG , Brazil.
FAU - Leyva Gonzalez, Maria Elena
AU  - Leyva Gonzalez ME
AUID- ORCID: 0000-0003-0673-5713
AD  - b Physics and Chemistry Institute (IFQ), Federal University of Itajuba (UNIFEI) , 
      Itajuba-MG , Brazil.
FAU - Caraballo, Mirta Mir
AU  - Caraballo MM
AD  - c Institute of Exact Sciences, ICEX - Federal University of Alfenas (Unifal-MG) , 
      Alfenas-MG , Brazil.
FAU - de Queiroz, Alvaro Antonio Alencar
AU  - de Queiroz AAA
AUID- ORCID: 0000-0002-1769-7022
AD  - d High Voltage Laboratory Prof. Manuel Luis Barreira Martinez 
      (LAT-EFEI)/Institute of Electrical Systems and Energy (ISEE), Federal University 
      of Itajuba-UNIFEI , Itajuba-MG , Brazil.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190709
PL  - England
TA  - J Biomater Sci Polym Ed
JT  - Journal of biomaterials science. Polymer edition
JID - 9007393
RN  - 0 (Biocompatible Materials)
RN  - 9004-34-6 (Cellulose)
SB  - IM
MH  - 3T3 Cells
MH  - Animals
MH  - Biocompatible Materials/*chemistry/*pharmacology
MH  - *Biomass
MH  - Cell Proliferation/drug effects
MH  - Cellulose/*chemistry/*pharmacology
MH  - *Electricity
MH  - Materials Testing
MH  - Mice
MH  - Surface Properties
MH  - Tissue Scaffolds/*chemistry
OTO - NOTNLM
OT  - BALB-3T3
OT  - Cellulose
OT  - scaffolds
EDAT- 2019/06/25 06:00
MHDA- 2020/07/11 06:00
CRDT- 2019/06/25 06:00
PHST- 2019/06/25 06:00 [pubmed]
PHST- 2020/07/11 06:00 [medline]
PHST- 2019/06/25 06:00 [entrez]
AID - 10.1080/09205063.2019.1636351 [doi]
PST - ppublish
SO  - J Biomater Sci Polym Ed. 2019 Oct;30(15):1399-1414. doi: 
      10.1080/09205063.2019.1636351. Epub 2019 Jul 9.