PMID- 31236353 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2222-3959 (Print) IS - 2227-4898 (Electronic) IS - 2222-3959 (Linking) VI - 12 IP - 6 DP - 2019 TI - Effect of femtosecond laser-assisted lens surgery on the optic nerve head and the macula. PG - 961-966 LID - 10.18240/ijo.2019.06.13 [doi] AB - AIM: To evaluate the effect of femtosecond laser-assisted lens surgery (FLALS; cataract surgery or refractive lens exchange) on the structure of the optic nerve head and the macula. METHODS: This prospective longitudinal study included healthy eyes undergoing FLALS. Eyes with glaucoma or any other ocular disease that could alter optical coherence tomography results were excluded. Retinal nerve fiber layer (RNFL), Bruch's membrane opening-minimum rim width (BMO-MRW) and macular thickness (MT) were measured preoperatively, 1 and 6mo after surgery using spectral-domain optical coherence tomography (SD-OCT). Changes between preoperative and postoperative values were evaluated. RESULTS: A total of 87 eyes of 46 patients were included in this study. Preoperative RNFL, BMO-MRW and MT in microns (microm) were 100.77+/-10.39, 330.31+/-49.99 and 276.30+/-33.39, respectively. Postoperative RNFL, BMO-MRW and MT were 104.74+/-11.55, 348.32+/-54.05 and 279.83+/-22.65 1mo after surgery and 102.93+/-11.17, 343.11+/-53.4 and 278.90+/-22.19 6mo after surgery, respectively; which equals an increase of 3.93%, 5.45% and 1.27%, respectively, 1mo after surgery, and 2.14%, 3.87% and 0.94% 6mo after surgery. The differences between the preoperative and the postoperative RNFL and BMO-MRW values were statistically significant (P<0.001). Regarding MT values, there were not statistically significant differences (P=0.26). CONCLUSION: Our study suggests that FLALS does not have a negative impact on the structural status of the optic nerve head in healthy eyes, assessed by SD-OCT. There is a slight increase in the values of RNFL, BMO-MRW and MT 1mo and 6mo after surgery. FAU - Renones de Abajo, Josefina AU - Renones de Abajo J AD - Eurocanarias Oftalmologica, Las Palmas de Gran Canaria 35004, Spain. AD - Universidad de Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria 35001, Spain. FAU - Estevez Jorge, Beatriz AU - Estevez Jorge B AD - Eurocanarias Oftalmologica, Las Palmas de Gran Canaria 35004, Spain. FAU - Gonzalez Martin, Jesus Maria AU - Gonzalez Martin JM AD - Department of Research, Hospital Universitario de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria 35019, Spain. FAU - Carreras Diaz, Humberto AU - Carreras Diaz H AD - Eurocanarias Oftalmologica, Las Palmas de Gran Canaria 35004, Spain. FAU - Loro Ferrer, Juan Francisco AU - Loro Ferrer JF AD - Universidad de Las Palmas de Gran Canaria (ULPGC), Las Palmas de Gran Canaria 35001, Spain. FAU - Anton Lopez, Alfonso AU - Anton Lopez A AD - Universidad Internacional de Cataluna (UIC), Barcelona 08195, Spain. AD - Institut Catala de Retina (ICR), Barcelona 08017, Spain. AD - Parc de salut Mar, Barcelona 08024, Spain. LA - eng PT - Journal Article DEP - 20190618 PL - China TA - Int J Ophthalmol JT - International journal of ophthalmology JID - 101553860 PMC - PMC6580205 OTO - NOTNLM OT - femtosecond laser-assisted cataract surgery OT - macula OT - optic nerve head OT - optical coherence tomography OT - refractive lens exchange EDAT- 2019/06/27 06:00 MHDA- 2019/06/27 06:01 PMCR- 2019/06/18 CRDT- 2019/06/26 06:00 PHST- 2018/10/02 00:00 [received] PHST- 2019/03/22 00:00 [accepted] PHST- 2019/06/26 06:00 [entrez] PHST- 2019/06/27 06:00 [pubmed] PHST- 2019/06/27 06:01 [medline] PHST- 2019/06/18 00:00 [pmc-release] AID - ijo-12-06-961 [pii] AID - 10.18240/ijo.2019.06.13 [doi] PST - epublish SO - Int J Ophthalmol. 2019 Jun 18;12(6):961-966. doi: 10.18240/ijo.2019.06.13. eCollection 2019.