PMID- 31237529 OWN - NLM STAT- MEDLINE DCOM- 20200608 LR - 20200608 IS - 1475-2662 (Electronic) IS - 0007-1145 (Linking) VI - 122 IP - 7 DP - 2019 Oct 14 TI - Association of the Dietary-Based Diabetes-Risk Score (DDS) with the risk of gestational diabetes mellitus in the Seguimiento Universidad de Navarra (SUN) project. PG - 800-807 LID - 10.1017/S0007114519001521 [doi] AB - It is crucial to identify people at risk for type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) to implement preventive interventions in order to address these pandemics. A simple score exclusively based on dietary components, the Dietary-Based Diabetes-Risk Score (DDS) showed a strong inverse association with incident T2DM. The objective was to assess the association between DDS and the risk of GDM in a cohort of Spanish university graduates. The 'Seguimiento Universidad de Navarra' project is a prospective and dynamic cohort which included data of 3455 women who notified pregnancies between 1999 and 2012. The diagnosis of GDM is self-reported and further confirmed by physicians. A validated 136-item semi-quantitative FFQ was used to assess pre-gestational dietary habits. The development of the DDS was aimed to quantify the association between the adherence to this a priori dietary score and T2DM incidence. The score exclusively included dietary components (nine food groups with reported inverse associations with T2DM incidence and three food groups which reported direct associations with T2DM). Three categories of adherence to the DDS were assessed: low (11-24), intermediate (25-39) and high (40-60). The upper category showed an independent inverse association with the risk of incident GDM compared with the lowest category (multivariate-adjusted OR 0.48; 95 % CI 0.24, 0.99; P for linear trend: 0.01). Several sensitivity analyses supported the robustness of these results. These results reinforce the importance of pre-gestational dietary habits for reducing GDM and provide a brief tool to practically assess the relevant dietary habits in clinical practice. FAU - Donazar-Ezcurra, Mikel AU - Donazar-Ezcurra M AD - Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain. AD - Department Obstetrics and Gynaecology, Complejo Hospitalario de Navarra-Osasunbidea-IDISNA, Pamplona, Spain. FAU - Lopez-Del Burgo, Cristina AU - Lopez-Del Burgo C AD - Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain. AD - CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain. AD - Navarra's Health Research Institute (IDISNA), Pamplona, Spain. AD - Institute for Culture and Society (ICS), University of Navarra, Pamplona, Spain. FAU - Martinez-Gonzalez, Miguel A AU - Martinez-Gonzalez MA AD - Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain. AD - CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain. AD - Navarra's Health Research Institute (IDISNA), Pamplona, Spain. AD - Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA. FAU - Dominguez, Ligia J AU - Dominguez LJ AD - Geriatric Unit - Department of Internal Medicine and Specialties, University of Palermo, Palermo, Italy. FAU - Basterra-Gortari, Francisco J AU - Basterra-Gortari FJ AD - Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain. AD - Navarra's Health Research Institute (IDISNA), Pamplona, Spain. AD - Department of Internal Medicine (Endocrinology), Hospital Reina Sofia, Osasunbidea-IDISNA, Tudela, Spain. FAU - de Irala, Jokin AU - de Irala J AD - Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain. AD - CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain. AD - Navarra's Health Research Institute (IDISNA), Pamplona, Spain. AD - Institute for Culture and Society (ICS), University of Navarra, Pamplona, Spain. FAU - Bes-Rastrollo, Maira AU - Bes-Rastrollo M AD - Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain. AD - CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn), Instituto de Salud Carlos III, Madrid, Spain. AD - Navarra's Health Research Institute (IDISNA), Pamplona, Spain. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Br J Nutr JT - The British journal of nutrition JID - 0372547 SB - IM MH - Adult MH - Cohort Studies MH - Diabetes, Gestational/*epidemiology MH - *Diet MH - Female MH - Humans MH - Pregnancy MH - Prospective Studies MH - Risk Factors MH - Spain/epidemiology MH - Young Adult OTO - NOTNLM OT - Cohort studies OT - Diabetes dietary score OT - Diabetes prevention OT - Gestational diabetes risk EDAT- 2019/06/27 06:00 MHDA- 2020/06/09 06:00 CRDT- 2019/06/26 06:00 PHST- 2019/06/27 06:00 [pubmed] PHST- 2020/06/09 06:00 [medline] PHST- 2019/06/26 06:00 [entrez] AID - S0007114519001521 [pii] AID - 10.1017/S0007114519001521 [doi] PST - ppublish SO - Br J Nutr. 2019 Oct 14;122(7):800-807. doi: 10.1017/S0007114519001521.