PMID- 31240556
OWN - NLM
STAT- MEDLINE
DCOM- 20210414
LR  - 20240213
IS  - 1873-4626 (Electronic)
IS  - 1091-255X (Linking)
VI  - 24
IP  - 3
DP  - 2020 Mar
TI  - LIFT and BioLIFT: a 10-Year Single-Centre Experience of Treating Complex 
      Fistula-In-Ano With Ligation of Intersphincteric Fistula Tract Procedure With or 
      Without Bio-prosthetic Reinforcement (BioLIFT).
PG  - 671-676
LID - 10.1007/s11605-019-04305-x [doi]
AB  - PURPOSE: To assess the outcome of ligation of intersphincteric fistula tract 
      (LIFT) and bioprosthetic graft (BioLIFT) in the management of transsphincteric 
      perianal fistula. METHODS: A single-institution retrospective analysis of all 
      patients undergoing LIFT and BioLIFT from January 2009 to June 2018 was 
      performed. Only patients who had LIFTs and BioLIFT performed as their primary 
      sphincter-preserving procedure was included. Primary outcome measured was primary 
      healing. Secondary outcomes measured were secondary healing, morbidity, time to 
      recurrence, and pre- and post-operative anorectal manometry. Chi-square analysis 
      was used to determine predictive factors. RESULTS: A total of 116 patients were 
      identified. One hundred five had LIFT and 11 had BioLIFT. The total primary 
      healing rate was 60.3% (62.9% and 34.9% for LIFT and BioLIFT respectively). The 
      overall secondary healing rate was 80.2% (80.0% and 81.9% for LIFT and BioLIFT 
      respectively). There was no inpatient morbidity or post-procedural faecal 
      incontinence reported. There was no significant change in the pre- and 
      post-operative manometries in either group (P = 0.417 and P = 0.834 for LIFT and 
      BioLIFT respectively). The only predictor for primary failure identified was 
      anteriorly located fistula. CONCLUSION: LIFT and BioLIFT compare favourably with 
      other sphincter-preserving procedures. LIFT and BioLIFT can be performed safely, 
      with minimal morbidity and with no reported loss of sphincteric function.
FAU - Lau, Yee Chen
AU  - Lau YC
AUID- ORCID: 0000-0001-7677-801X
AD  - Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, 
      Australia. ychenlau@gmail.com.
AD  - Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, PO Box 
      M157, Missenden Road, Sydney, NSW, 2050, Australia. ychenlau@gmail.com.
FAU - Brown, Kilian G M
AU  - Brown KGM
AD  - Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, 
      Australia.
AD  - Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, PO Box 
      M157, Missenden Road, Sydney, NSW, 2050, Australia.
AD  - The Institute of Academic Surgery at RPA, Sydney, Australia.
FAU - Cheong, Juyong
AU  - Cheong J
AD  - Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, 
      Australia.
AD  - Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, PO Box 
      M157, Missenden Road, Sydney, NSW, 2050, Australia.
FAU - Byrne, Christopher
AU  - Byrne C
AD  - Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, 
      Australia.
AD  - Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, PO Box 
      M157, Missenden Road, Sydney, NSW, 2050, Australia.
AD  - The Institute of Academic Surgery at RPA, Sydney, Australia.
FAU - Lee, Peter J
AU  - Lee PJ
AD  - Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, 
      Australia.
AD  - Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, PO Box 
      M157, Missenden Road, Sydney, NSW, 2050, Australia.
AD  - The Institute of Academic Surgery at RPA, Sydney, Australia.
LA  - eng
PT  - Journal Article
DEP - 20190625
PL  - Netherlands
TA  - J Gastrointest Surg
JT  - Journal of gastrointestinal surgery : official journal of the Society for Surgery 
      of the Alimentary Tract
JID - 9706084
SB  - IM
MH  - Anal Canal/surgery
MH  - Humans
MH  - Ligation
MH  - *Neoplasm Recurrence, Local
MH  - *Rectal Fistula/surgery
MH  - Recurrence
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - BioLIFT
OT  - LIFT
OT  - Ligation of intersphincteric tract
OT  - Perianal fistula
EDAT- 2019/06/27 06:00
MHDA- 2021/04/15 06:00
CRDT- 2019/06/27 06:00
PHST- 2019/04/13 00:00 [received]
PHST- 2019/06/10 00:00 [accepted]
PHST- 2019/06/27 06:00 [pubmed]
PHST- 2021/04/15 06:00 [medline]
PHST- 2019/06/27 06:00 [entrez]
AID - S1091-255X(23)01408-7 [pii]
AID - 10.1007/s11605-019-04305-x [doi]
PST - ppublish
SO  - J Gastrointest Surg. 2020 Mar;24(3):671-676. doi: 10.1007/s11605-019-04305-x. 
      Epub 2019 Jun 25.