PMID- 31244642
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1662-6575 (Print)
IS  - 1662-6575 (Electronic)
IS  - 1662-6575 (Linking)
VI  - 12
IP  - 2
DP  - 2019 May-Aug
TI  - Mediastinal Lymphoma Presenting in Cardiogenic Shock with Superior Vena Cava 
      Syndrome in a Primigravida at Full Term: Salvage Resection after Prolonged 
      Extracorporeal Life Support.
PG  - 401-410
LID - 10.1159/000499195 [doi]
AB  - Primary mediastinal large B-cell lymphoma (PMBCL) is a rare type of non-Hodgkin 
      lymphoma that typically has a good response rate to first line chemotherapy 
      regimens. There have been reports of successful chemotherapy, but with a residual 
      mass from fibrosis. Here, we report the case of a 19-year-old primigravida 
      presenting with cardiogenic shock and superior vena cava (SVC) syndrome at full 
      term who was found to have a PMBCL. Following delivery via urgent cesarean 
      section, she was put on veno-arterial extra corporeal membrane oxygenation 
      (VA-ECMO) and once hemodynamically stable was started on chemotherapy. In view of 
      limited change in tumor size on consecutive CT scans and questionable response to 
      chemotherapy, there were multidisciplinary meetings wherein withdrawing support 
      was discussed and put forward to the family. At that point, surgical debulking 
      was offered on compassionate grounds to be able to wean her off the VA-ECMO. This 
      case report highlights the role of salvage resection when there are no other 
      options.
FAU - Carro, Sabrina E
AU  - Carro SE
AD  - MD Candidate 2020, Lewis Katz School of Medicine at Temple University, 
      Philadelphia, Pennsylvania, USA.
FAU - Essex, David W
AU  - Essex DW
AD  - Department of Hematology and Oncology, Temple University Hospital, Philadelphia, 
      Pennsylvania, USA.
FAU - Alsammak, Mohamed
AU  - Alsammak M
AD  - Department of Pathology and Laboratory Medicine, Temple University Hospital, 
      Philadelphia, Pennsylvania, USA.
FAU - Bains, Ashish
AU  - Bains A
AD  - Department of Pathology and Laboratory Medicine, Temple University Hospital, 
      Philadelphia, Pennsylvania, USA.
FAU - Toyoda, Yoshiya
AU  - Toyoda Y
AD  - Department of Cardiovascular Surgery, Temple University Hospital, Philadelphia, 
      Pennsylvania, USA.
FAU - Keshavamurthy, Suresh
AU  - Keshavamurthy S
AD  - Department of Cardiovascular Surgery, Temple University Hospital, Philadelphia, 
      Pennsylvania, USA.
LA  - eng
PT  - Case Reports
DEP - 20190604
PL  - Switzerland
TA  - Case Rep Oncol
JT  - Case reports in oncology
JID - 101517601
PMC - PMC6587197
OTO - NOTNLM
OT  - ECMO
OT  - Extracorporeal membrane oxygenation
OT  - Lymphoma, mediastinal mass
OT  - Non-Hodgkin
OT  - PMBCL
OT  - Pathology
OT  - Salvage resection
OT  - Surgery
EDAT- 2019/06/28 06:00
MHDA- 2019/06/28 06:01
PMCR- 2019/06/04
CRDT- 2019/06/28 06:00
PHST- 2019/02/27 00:00 [received]
PHST- 2019/02/27 00:00 [accepted]
PHST- 2019/06/28 06:00 [entrez]
PHST- 2019/06/28 06:00 [pubmed]
PHST- 2019/06/28 06:01 [medline]
PHST- 2019/06/04 00:00 [pmc-release]
AID - cro-0012-0401 [pii]
AID - 10.1159/000499195 [doi]
PST - epublish
SO  - Case Rep Oncol. 2019 Jun 4;12(2):401-410. doi: 10.1159/000499195. eCollection 
      2019 May-Aug.