PMID- 31245335
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2296-2360 (Print)
IS  - 2296-2360 (Electronic)
IS  - 2296-2360 (Linking)
VI  - 7
DP  - 2019
TI  - Extracorporeal Membrane Oxygenation Support for Cardiac Dysfunction Due to 
      Kawasaki Disease Shock Syndrome.
PG  - 221
LID - 10.3389/fped.2019.00221 [doi]
LID - 221
AB  - Background: Kawasaki disease (KD) is usually characterized as an inflammatory 
      vasculitis during early childhood, which predominantly involves medium-sized 
      arteries and is treated with intravenous gamma-globulin (IVIG) and oral aspirin. KD 
      with hemodynamic instability, characterized by systolic blood pressure decreasing 
      by more than 20% below the normal range, is defined as Kawasaki disease shock 
      syndrome (KDSS). The pathogenesis of KDSS is still not comprehensively 
      understood. Life-threatening cardiogenic shock can occur during the acute phase 
      of KDSS, while the mechanism of cardiac dysfunction due to KDSS is still 
      controversial, and such cases are rarely reported. Here, we present the 
      application of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) for 
      cardiac function support of a child with KDSS. By doing so, it will be a reminder 
      that KDSS can cause severe cardiac dysfunction, and we should stay vigilant at 
      the early stage of the disease to distinguish KDSS from toxic septic shock in the 
      first place and initiate the appropriate treatment at the right moment, in order 
      to prevent such patients from having irreversible outcomes.
FAU - Zhang, Han
AU  - Zhang H
AD  - Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong 
      University, Shanghai, China.
FAU - Xie, Lijian
AU  - Xie L
AD  - Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong 
      University, Shanghai, China.
FAU - Xiao, Tingting
AU  - Xiao T
AD  - Department of Cardiology, Shanghai Children's Hospital, Shanghai Jiaotong 
      University, Shanghai, China.
LA  - eng
PT  - Case Reports
DEP - 20190606
PL  - Switzerland
TA  - Front Pediatr
JT  - Frontiers in pediatrics
JID - 101615492
PMC - PMC6563758
OTO - NOTNLM
OT  - Kawasaki disease
OT  - Kawasaki disease shock syndrome
OT  - cardiogenic shock
OT  - extracorporeal membrane oxygenation
OT  - intravenous gamma-globulin resistance
EDAT- 2019/06/28 06:00
MHDA- 2019/06/28 06:01
PMCR- 2019/06/06
CRDT- 2019/06/28 06:00
PHST- 2019/03/03 00:00 [received]
PHST- 2019/05/16 00:00 [accepted]
PHST- 2019/06/28 06:00 [entrez]
PHST- 2019/06/28 06:00 [pubmed]
PHST- 2019/06/28 06:01 [medline]
PHST- 2019/06/06 00:00 [pmc-release]
AID - 10.3389/fped.2019.00221 [doi]
PST - epublish
SO  - Front Pediatr. 2019 Jun 6;7:221. doi: 10.3389/fped.2019.00221. eCollection 2019.