PMID- 31245919 OWN - NLM STAT- MEDLINE DCOM- 20200219 LR - 20221207 IS - 1756-185X (Electronic) IS - 1756-1841 (Linking) VI - 22 IP - 9 DP - 2019 Sep TI - Cross-cultural adaptation of the Hamilton axial spondyloarthritis questionnaire and development of a Chinese version in a multi-ethnic Asian population. PG - 1652-1660 LID - 10.1111/1756-185X.13645 [doi] AB - OBJECTIVE: To cross-culturally adapt the Hamilton axial spondyloarthritis (axial SpA) screening questionnaire and develop a Chinese version for use in a multi-ethnic Asian population in Singapore. METHODS: Consenting participants newly referred from primary care to a rheumatology specialist outpatient clinic for evaluation of possible axial SpA were studied. The original axial SpA questionnaire was revised based on inputs from cognitive debriefing interviews (CDIs) and discussions with an expert panel of rheumatologists and the developer. Forward and back translations of the adapted English version were also reviewed by the expert panel and the developer. The common translation produced was tested in CDIs with Chinese-speaking participants. Adapted English and Chinese versions were pilot-tested in a separate group of similar participants. RESULTS: Participants were recruited for English (n = 25) and Chinese CDIs (n = 15, relatively older and less frequently presented with axial SpA symptoms), respectively. Alternative terms and explanatory notes were added to difficult medical terms to improve the understandability of the adapted English version. English medical terms were retained in the Chinese version. Pilot-testing of the adapted axial SpA questionnaire was performed on 116 participants, all of whom reported ease of comprehension with both adapted versions. Only one participant was diagnosed with axial SpA, who also scored positive on the adapted axial SpA questionnaire. CONCLUSION: The adapted axial SpA questionnaire demonstrated good sensitivity in the pilot-testing and appears to be a promising tool for facilitating early identification of axial SpA cases in the multi-ethnic Asian population. CI - (c) 2019 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd. FAU - Xiang, Ling AU - Xiang L AD - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore City, Singapore. FAU - Teo, Edmund Pek Siang AU - Teo EPS AD - Health Services Research Unit, Singapore General Hospital, Singapore City, Singapore. FAU - Low, Andrea Hsiu Ling AU - Low AHL AD - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore City, Singapore. AD - Duke-NUS Medical School, Singapore City, Singapore. AD - Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore. FAU - Leung, Ying Ying AU - Leung YY AUID- ORCID: 0000-0001-8492-6342 AD - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore City, Singapore. AD - Duke-NUS Medical School, Singapore City, Singapore. AD - Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore. FAU - Fong, Warren AU - Fong W AD - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore City, Singapore. AD - Duke-NUS Medical School, Singapore City, Singapore. AD - Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore. FAU - Xin, Xiaohui AU - Xin X AD - Academic Clinical Program for Medicine, Singapore General Hospital, Singapore City, Singapore. FAU - Gandhi, Mihir AU - Gandhi M AD - Biostatistics, Singapore Clinical Research Institute, Singapore City, Singapore. AD - Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore City, Singapore. FAU - Kwan, Yu Heng AU - Kwan YH AUID- ORCID: 0000-0001-7802-9696 AD - Duke-NUS Medical School, Singapore City, Singapore. FAU - Uy, Elenore J B AU - Uy EJB AD - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore City, Singapore. FAU - Hamilton, Louise AU - Hamilton L AD - Department of Rheumatology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK. FAU - Thumboo, Julian AU - Thumboo J AUID- ORCID: 0000-0001-6712-5535 AD - Department of Rheumatology and Immunology, Singapore General Hospital, Singapore City, Singapore. AD - Duke-NUS Medical School, Singapore City, Singapore. AD - Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore. LA - eng GR - NMRC/HSRG/0075/2017/Singapore Ministry of Health National Medical Research Council/ PT - Journal Article DEP - 20190627 PL - England TA - Int J Rheum Dis JT - International journal of rheumatic diseases JID - 101474930 SB - IM MH - Adult MH - Aged MH - *Asian People MH - China/epidemiology MH - Comprehension MH - Cross-Sectional Studies MH - *Cultural Characteristics MH - Female MH - Humans MH - Male MH - Middle Aged MH - Pilot Projects MH - Predictive Value of Tests MH - Reproducibility of Results MH - Severity of Illness Index MH - Spondylarthritis/*diagnosis/ethnology/physiopathology MH - *Surveys and Questionnaires MH - Translating OTO - NOTNLM OT - ankylosing spondylitis OT - epidemiology OT - health services and health care economics EDAT- 2019/06/28 06:00 MHDA- 2020/02/20 06:00 CRDT- 2019/06/28 06:00 PHST- 2018/09/26 00:00 [received] PHST- 2019/05/18 00:00 [revised] PHST- 2019/05/31 00:00 [accepted] PHST- 2019/06/28 06:00 [pubmed] PHST- 2020/02/20 06:00 [medline] PHST- 2019/06/28 06:00 [entrez] AID - 10.1111/1756-185X.13645 [doi] PST - ppublish SO - Int J Rheum Dis. 2019 Sep;22(9):1652-1660. doi: 10.1111/1756-185X.13645. Epub 2019 Jun 27.