PMID- 31247721
OWN - NLM
STAT- MEDLINE
DCOM- 20200918
LR  - 20200918
IS  - 1520-6882 (Electronic)
IS  - 0003-2700 (Print)
IS  - 0003-2700 (Linking)
VI  - 91
IP  - 13
DP  - 2019 Jul 2
TI  - Fully Automated Online Dynamic In-Tube Extraction for Continuous Sampling of 
      Volatile Organic Compounds in Air.
PG  - 8507-8515
LID - 10.1021/acs.analchem.9b01668 [doi]
AB  - Comprehensive and time-dependent information (e.g., chemical composition, 
      concentration) of volatile organic compounds (VOCs) in atmospheric, indoor, and 
      breath air is essential to understand the fundamental science of the atmosphere, 
      air quality, and diseases diagnostic. Here, we introduced a fully automated 
      online dynamic in-tube extraction (ITEX)-gas chromatography/mass spectrometry 
      (GC/MS) method for continuous and quantitative monitoring of VOCs in air. In this 
      approach, modified Cycle Composer software and a PAL autosampler controlled and 
      operated the ITEX preconditioning, internal standard (ISTD) addition, air 
      sampling, and ITEX desorption sequentially to enable full automation. Air flow 
      passed through the ITEX with the help of an external pump, instead of plunger 
      up-down strokes, to allow larger sampling volumes, exhaustive extraction, and 
      consequently lower detection limits. Further, in order to evaluate the ITEX 
      system stability and to develop the corresponding quantitative ITEX method, two 
      laboratory-made permeation systems (for standard VOCs and ISTD) were constructed. 
      The stability and suitability of the developed system was validated with a 
      consecutive 19 day atmospheric air campaign under automation. By using an 
      electrospun polyacrylonitrile nanofibers packed ITEX, selective extraction of 
      some VOCs and durability of over 1500 extraction and desorption cycles were 
      achieved. Especially, the latter step is critically important for on-site 
      long-term application at remote regions. This ITEX method provided 2-3 magnitudes 
      lower quantitation limits than the headspace dynamic ITEX method and other needle 
      trap methods. Our results proved the excellence of the fully automated online 
      dynamic ITEX-GC/MS system for tracking VOCs in the atmospheric air.
FAU - Lan, Hangzhen
AU  - Lan H
AD  - Department of Chemistry , University of Helsinki , P.O. Box 55, 00014 Helsinki , 
      Finland.
AD  - Institute for Atmospheric and Earth System Research , University of Helsinki , 
      P.O. Box 64, 00014 Helsinki , Finland.
FAU - Holopainen, Jani
AU  - Holopainen J
AUID- ORCID: 0000-0002-9648-5430
AD  - Department of Chemistry , University of Helsinki , P.O. Box 55, 00014 Helsinki , 
      Finland.
FAU - Hartonen, Kari
AU  - Hartonen K
AUID- ORCID: 0000-0003-4821-2355
AD  - Department of Chemistry , University of Helsinki , P.O. Box 55, 00014 Helsinki , 
      Finland.
AD  - Institute for Atmospheric and Earth System Research , University of Helsinki , 
      P.O. Box 64, 00014 Helsinki , Finland.
FAU - Jussila, Matti
AU  - Jussila M
AD  - Department of Chemistry , University of Helsinki , P.O. Box 55, 00014 Helsinki , 
      Finland.
AD  - Institute for Atmospheric and Earth System Research , University of Helsinki , 
      P.O. Box 64, 00014 Helsinki , Finland.
FAU - Ritala, Mikko
AU  - Ritala M
AUID- ORCID: 0000-0002-6210-2980
AD  - Department of Chemistry , University of Helsinki , P.O. Box 55, 00014 Helsinki , 
      Finland.
FAU - Riekkola, Marja-Liisa
AU  - Riekkola ML
AUID- ORCID: 0000-0001-7519-9892
AD  - Department of Chemistry , University of Helsinki , P.O. Box 55, 00014 Helsinki , 
      Finland.
AD  - Institute for Atmospheric and Earth System Research , University of Helsinki , 
      P.O. Box 64, 00014 Helsinki , Finland.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190619
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
RN  - 0 (Air Pollutants)
RN  - 0 (Volatile Organic Compounds)
SB  - IM
MH  - Air Pollutants/*analysis
MH  - Automation
MH  - Chemical Fractionation/*methods
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Limit of Detection
MH  - Volatile Organic Compounds/*analysis
PMC - PMC6750644
COIS- The authors declare no competing financial interest.
EDAT- 2019/06/30 06:00
MHDA- 2020/09/20 06:00
PMCR- 2019/09/18
CRDT- 2019/06/29 06:00
PHST- 2019/06/30 06:00 [pubmed]
PHST- 2020/09/20 06:00 [medline]
PHST- 2019/06/29 06:00 [entrez]
PHST- 2019/09/18 00:00 [pmc-release]
AID - 10.1021/acs.analchem.9b01668 [doi]
PST - ppublish
SO  - Anal Chem. 2019 Jul 2;91(13):8507-8515. doi: 10.1021/acs.analchem.9b01668. Epub 
      2019 Jun 19.