PMID- 31257414
OWN - NLM
STAT- MEDLINE
DCOM- 20200302
LR  - 20200302
IS  - 1569-9285 (Electronic)
IS  - 1569-9285 (Linking)
VI  - 29
IP  - 5
DP  - 2019 Nov 1
TI  - Venoarterial extracorporeal membrane oxygenation with or without simultaneous 
      intra-aortic balloon pump support as a direct bridge to heart transplantation: 
      results from a nationwide Spanish registry.
PG  - 670-677
LID - 10.1093/icvts/ivz155 [doi]
AB  - OBJECTIVES: To investigate the potential clinical benefit of an intra-aortic 
      balloon pump (IABP) in patients supported with venoarterial extracorporeal 
      membrane oxygenation (VA-ECMO) as a bridge to heart transplantation (HT). 
      METHODS: We studied 169 patients who were listed for urgent HT under VA-ECMO 
      support at 16 Spanish institutions from 2010 to 2015. The clinical outcomes of 
      patients under simultaneous IABP support (n = 73) were compared to a control 
      group of patients without IABP support (n = 96). RESULTS: There were no 
      statistically significant differences between the IABP and control groups with 
      regard to the cumulative rates of transplantation (71.2% vs 81.2%, P = 0.17), 
      death during VA-ECMO support (20.6% vs 14.6%, P = 0.31), transition to a 
      different mechanical circulatory support device (5.5% vs 5.2%, P = 0.94) or 
      weaning from VA-ECMO support due to recovery (2.7% vs 0%, P = 0.10). There was a 
      higher incidence of bleeding events in the IABP group (45.2% vs 25%, P = 0.006; 
      adjusted odds ratio 2.18, 95% confidence interval 1.02-4.67). In-hospital 
      postoperative mortality after HT was 34.6% in the IABP group and 32.5% in the 
      control group (P = 0.80). One-year survival after listing for urgent HT was 53.3% 
      in the IABP group and 52.2% in the control group (log rank P = 0.75). 
      Multivariate adjustment for potential confounders did not change this result 
      (adjusted hazard ratio 0.94, 95% confidence interval 0.56-1.58). CONCLUSIONS: In 
      our study, simultaneous IABP therapy in transplant candidates under VA-ECMO 
      support did not significantly reduce morbidity or mortality.
CI  - (c) The Author(s) 2019. Published by Oxford University Press on behalf of the 
      European Association for Cardio-Thoracic Surgery. All rights reserved.
FAU - Barge-Caballero, Gonzalo
AU  - Barge-Caballero G
AD  - Complejo Hospitalario Universitario A Coruna (CHUAC), Instituto de Investigacion 
      Biomedica de A Coruna (INIBIC), A Coruna, Spain.
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
FAU - Castel-Lavilla, Maria A
AU  - Castel-Lavilla MA
AD  - Hospital Clinic i Provincial, Barcelona, Spain.
FAU - Almenar-Bonet, Luis
AU  - Almenar-Bonet L
AD  - Hospital Universitario y Politecnico La Fe, Valencia, Spain.
FAU - Garrido-Bravo, Iris P
AU  - Garrido-Bravo IP
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
AD  - Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
FAU - Delgado, Juan F
AU  - Delgado JF
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
AD  - Hospital Universitario Doce de Octubre, Instituto de Investigacion i+12, Facultad 
      de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
FAU - Rangel-Sousa, Diego
AU  - Rangel-Sousa D
AD  - Hospital Universitario Virgen del Rocio, Sevilla, Spain.
FAU - Gonzalez-Costello, Jose
AU  - Gonzalez-Costello J
AD  - Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Spain.
FAU - Segovia-Cubero, Javier
AU  - Segovia-Cubero J
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
AD  - Hospital Universitario Puerta de Hierro, Majadahonda, Spain.
FAU - Farrero-Torres, Marta
AU  - Farrero-Torres M
AD  - Hospital Clinic i Provincial, Barcelona, Spain.
FAU - Lambert-Rodriguez, Jose Luis
AU  - Lambert-Rodriguez JL
AD  - Hospital Universitario Central de Asturias, Oviedo, Spain.
AD  - Universidad Catolica San Antonio, Murcia, Spain.
FAU - Crespo-Leiro, Maria G
AU  - Crespo-Leiro MG
AD  - Complejo Hospitalario Universitario A Coruna (CHUAC), Instituto de Investigacion 
      Biomedica de A Coruna (INIBIC), A Coruna, Spain.
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
FAU - Hervas-Sotomayor, Daniela
AU  - Hervas-Sotomayor D
AD  - Hospital Universitario Reina Sofia, Cordoba, Spain.
FAU - Portoles-Ocampo, Ana
AU  - Portoles-Ocampo A
AD  - Hospital Universitario Miguel Servet, Zaragoza, Spain.
FAU - Martinez-Selles, Manuel
AU  - Martinez-Selles M
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
AD  - Hospital General Universitario Gregorio Maranon, Universidad Complutense, 
      Universidad Europea, Madrid, Spain.
FAU - De la Fuente-Galan, Luis
AU  - De la Fuente-Galan L
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
AD  - Hospital Clinico Universitario, Valladolid, Spain.
FAU - Rabago-Juan-Aracil, Gregorio
AU  - Rabago-Juan-Aracil G
AD  - Clinica Universidad de Navarra, Pamplona, Spain.
FAU - Gonzalez-Vilchez, Francisco
AU  - Gonzalez-Vilchez F
AD  - Hospital Universitario Marques de Valdecilla, Santander, Spain.
FAU - Mirabet-Perez, Sonia
AU  - Mirabet-Perez S
AD  - Hospital Santa Creu i Sant Pau, Barcelona, Spain.
FAU - Muniz, Javier
AU  - Muniz J
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
AD  - Instituto Universitario de Ciencias de la Salud, Universidad de A Coruna (UDC), 
      INIBIC, A Coruna, Spain.
FAU - Barge-Caballero, Eduardo
AU  - Barge-Caballero E
AD  - Complejo Hospitalario Universitario A Coruna (CHUAC), Instituto de Investigacion 
      Biomedica de A Coruna (INIBIC), A Coruna, Spain.
AD  - Centro de Investigacion Biomedica en Red de Enfermedades Cardiovasculares 
      (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Interact Cardiovasc Thorac Surg
JT  - Interactive cardiovascular and thoracic surgery
JID - 101158399
SB  - IM
MH  - Extracorporeal Membrane Oxygenation/*methods
MH  - Female
MH  - Heart Failure/mortality/*surgery
MH  - Heart Transplantation/*methods
MH  - Hospital Mortality/trends
MH  - Humans
MH  - Intra-Aortic Balloon Pumping/*methods
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - *Registries
MH  - Retrospective Studies
MH  - Spain/epidemiology
MH  - Survival Rate/trends
OTO - NOTNLM
OT  - Extracorporeal membrane oxygenation
OT  - Heart transplantation
OT  - Intra-aortic balloon pump
EDAT- 2019/07/02 06:00
MHDA- 2020/03/03 06:00
CRDT- 2019/07/02 06:00
PHST- 2018/12/17 00:00 [received]
PHST- 2019/05/14 00:00 [revised]
PHST- 2019/05/19 00:00 [accepted]
PHST- 2019/07/02 06:00 [pubmed]
PHST- 2020/03/03 06:00 [medline]
PHST- 2019/07/02 06:00 [entrez]
AID - 5525333 [pii]
AID - 10.1093/icvts/ivz155 [doi]
PST - ppublish
SO  - Interact Cardiovasc Thorac Surg. 2019 Nov 1;29(5):670-677. doi: 
      10.1093/icvts/ivz155.