PMID- 31261578
OWN - NLM
STAT- MEDLINE
DCOM- 20190708
LR  - 20221005
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 98
IP  - 26
DP  - 2019 Jun
TI  - Prevalence and associated factors of mortality after percutaneous coronary 
      intervention for adult patients with ST elevation myocardial infarction: A 
      systematic review and meta-analysis protocol.
PG  - e16226
LID - 10.1097/MD.0000000000016226 [doi]
LID - e16226
AB  - BACKGROUND: The percutaneous coronary intervention (PCI) has been one of the 
      fastest growing therapeutic interventions for patients with ST elevation 
      myocardial infarction (STEMI). However, the mortality of patients with STEMI 
      after PCI is uncertain currently. There is a paucity of systematic review on the 
      associated factors of mortality among patients with STEMI after PCI. Therefore, 
      this meta-analysis was designed to synthesize available evidence on the 
      prevalence and associated factors of mortality after PCI for adult patients with 
      STEMI. METHODS: Both case-control and cohort studies reporting on mortality after 
      PCI for patients with STEMI, published in Chinese and English will be eligible 
      for inclusion. Studies from 12 databases covering the period from 2008 to present 
      will be considered for systematic searches. Two reviewers will independently 
      screen and select studies, extract data, and assess methodologic quality. When 
      available, meta-analysis will be performed. Pooled proportions of mortality, and 
      proportions in the exposed and unexposed groups, and population attributable 
      fraction of each factor will be calculated by a suitable transformation of 
      proportions. If necessary, meta-regression models, subgroup analysis, sensitivity 
      analysis, funnel plot, and Egger test will be performed. Narrative synthesis will 
      be done where meta-analysis cannot be performed. Reporting of this protocol will 
      comply with the preferred reporting items for systematic review and meta-analyses 
      (PRISMA-P) guidelines. RESULTS: This systematic review will be developed 
      according to the meta-analysis of observational studies in epidemiology (MOOSE) 
      guidelines. CONCLUSION: This study will provide a comprehensive review on the 
      available evidence regarding the prevalence and associated factors of mortality 
      for patients with STEMI following PCI. This review will be constrained by the 
      divergence of definition and assessment of specific factors between studies. 
      However, the development of a qualitative description of definition and 
      assessment tools will also provide an overview of the current practice. Formal 
      ethical approval is not required since the secondary data will be collected for 
      systematic review. The findings will be disseminated in a relevant peer-reviewed 
      journal and academic presentations. SYSTEMATIC REVIEW REGISTRATION: PROSPERO 
      CRD42017070969.
FAU - Yan, Fanghong
AU  - Yan F
AD  - Xi'an Jiaotong University Health Science Center, Shaanxi Province.
AD  - Lanzhou University, School of Nursing, Gansu Province, China.
FAU - Liu, Huan
AU  - Liu H
AD  - Xi'an Jiaotong University Health Science Center, Shaanxi Province.
FAU - Jiang, Wenhui
AU  - Jiang W
AD  - Xi'an Jiaotong University Health Science Center, Shaanxi Province.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Cohort Studies
MH  - Humans
MH  - *Meta-Analysis as Topic
MH  - *Percutaneous Coronary Intervention
MH  - Research Design
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*mortality/*surgery
MH  - *Systematic Reviews as Topic
PMC - PMC6617472
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2019/07/03 06:00
MHDA- 2019/07/10 06:00
PMCR- 2019/06/28
CRDT- 2019/07/03 06:00
PHST- 2019/07/03 06:00 [entrez]
PHST- 2019/07/03 06:00 [pubmed]
PHST- 2019/07/10 06:00 [medline]
PHST- 2019/06/28 00:00 [pmc-release]
AID - 00005792-201906280-00089 [pii]
AID - MD-D-19-04346 [pii]
AID - 10.1097/MD.0000000000016226 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2019 Jun;98(26):e16226. doi: 10.1097/MD.0000000000016226.