PMID- 31263505 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220409 IS - 1741-427X (Print) IS - 1741-4288 (Electronic) IS - 1741-427X (Linking) VI - 2019 DP - 2019 TI - A Study on the Development of a Korean Metabolic Syndrome Questionnaire Using Blood Stasis Clinical Data. PG - 8761417 LID - 10.1155/2019/8761417 [doi] LID - 8761417 AB - OBJECTIVE: The aims of this study were to extract clinical indicators related to metabolic diseases using the Blood Stasis Questionnaires I and II (BSQ-I and II) developed in 2013 and 2014, respectively, and to develop a BSQ on metabolic syndrome (BSQ-MS). METHODS: A total of 2,158 patients, comprising 1,214 from 7 traditional Korean medical hospitals in 2013 and 944 from 3 traditional Korean medical hospitals in 2014, were asked to complete the BSQ-I and BSQ-II. For the 370 patients who met the metabolic syndrome criteria, reliability and validity of the BSQ-MS were assessed using Cronbach's alpha, while prediction accuracy was determined by logistic regression. RESULTS: The BSQ-MS included a total of 15 clinical signs and symptoms. It showed satisfactory internal consistency (Cronbach's alpha coefficient=0.70) and validity, with significant differences in mean scores between the blood stasis (14.09+/-6.14) and non-blood stasis (9.09+/-5.60) subject groups. The cut-off value of BSQ-MS score was 9 points, the area under the receiver operating characteristic curve was approximately 77%, the sensitivity and specificity of the diagnostic accuracy according to the cut-off value were 82.9% and 49.7%, respectively, and the sensitivity and specificity of the prediction accuracy by logistic regression were 72.2% and 71.6%, respectively. CONCLUSION: These results suggest that the BSQ-MS is an appropriate instrument for estimating blood stasis in patients with metabolic syndrome, although its sensitivity for diagnosis according to the cut-off value is low. FAU - Kang, Byoung-Kab AU - Kang BK AD - Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. FAU - Jang, Soobin AU - Jang S AUID- ORCID: 0000-0003-0943-9290 AD - Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. FAU - Ko, Mi Mi AU - Ko MM AUID- ORCID: 0000-0002-5758-4655 AD - Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. FAU - Jung, Jeeyoun AU - Jung J AUID- ORCID: 0000-0002-9213-4748 AD - Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea. LA - eng PT - Journal Article DEP - 20190527 PL - United States TA - Evid Based Complement Alternat Med JT - Evidence-based complementary and alternative medicine : eCAM JID - 101215021 PMC - PMC6556799 EDAT- 2019/07/03 06:00 MHDA- 2019/07/03 06:01 PMCR- 2019/05/27 CRDT- 2019/07/03 06:00 PHST- 2019/02/13 00:00 [received] PHST- 2019/04/16 00:00 [accepted] PHST- 2019/07/03 06:00 [entrez] PHST- 2019/07/03 06:00 [pubmed] PHST- 2019/07/03 06:01 [medline] PHST- 2019/05/27 00:00 [pmc-release] AID - 10.1155/2019/8761417 [doi] PST - epublish SO - Evid Based Complement Alternat Med. 2019 May 27;2019:8761417. doi: 10.1155/2019/8761417. eCollection 2019.