PMID- 31266799
OWN - NLM
STAT- MEDLINE
DCOM- 20200831
LR  - 20240229
IS  - 1532-2548 (Electronic)
IS  - 0032-0889 (Print)
IS  - 0032-0889 (Linking)
VI  - 181
IP  - 1
DP  - 2019 Sep
TI  - A Multiprotein Complex Regulates Interference-Sensitive Crossover Formation in 
      Rice.
PG  - 221-235
LID - 10.1104/pp.19.00082 [doi]
AB  - In most eukaryotes, a set of conserved proteins that are collectively termed ZMM 
      proteins (named for molecular zipper 1 [ZIP1], ZIP2, ZIP3, and ZIP4, MutS 
      homologue 4 [MSH4] and MSH5, meiotic recombination 3, and sporulation 16 [SPO16] 
      in yeast [Saccharomyces cerevisiae]) are essential for the formation of the 
      majority of meiotic crossovers (COs). Recent reports indicated that ZIP2 acts 
      together with SPO16 and ZIP4 to control CO formation through recognizing and 
      stabilizing early recombination intermediates in budding yeast. However, whether 
      this mechanism is conserved in plants is not clear. Here, we characterized the 
      functions of SHORTAGE OF CHIASMATA 1 (OsSHOC1; ZIP2 ortholog) and PARTING DANCERS 
      (OsPTD; SPO16 ortholog) and their interactions with other ZMM proteins in rice 
      (Oryza sativa). We demonstrated that disruption of OsSHOC1 caused a reduction of 
      CO numbers to  approximately 83% of wild-type CO numbers, whereas synapsis and early meiotic 
      recombination steps were not affected. Furthermore, OsSHOC1 interacts with OsPTD, 
      which is responsible for the same set of CO formations as OsSHOC1. In addition, 
      OsSHOC1 and OsPTD are required for the normal loading of other ZMM proteins, and 
      conversely, the localizations of OsSHOC1 and OsPTD were also affected by the 
      absence of OsZIP4 and human enhancer of invasion 10 in rice (OsHEI10). OsSHOC1 
      interacts with OsZIP4 and OsMSH5, and OsPTD interacts with OsHEI10. Furthermore, 
      bimolecular fluorescence complementation and yeast-three hybrid assays 
      demonstrated that OsSHOC1, OsPTD, OsHEI10, and OsZIP4 were able to form various 
      combinations of heterotrimers. Moreover, statistical and genetic analysis 
      indicated that OsSHOC1 and OsPTD are epistatic to OsHEI10 and OsZIP4 in meiotic 
      CO formation. Taken together, we propose that OsSHOC1, OsPTD, OsHEI10, and OsZIP4 
      form multiple protein complexes that have conserved functions in promoting class 
      I CO formation.
CI  - (c) 2019 American Society of Plant Biologists. All Rights Reserved.
FAU - Zhang, Jie
AU  - Zhang J
AUID- ORCID: 0000-0003-4725-8407
AD  - Joint International Research Laboratory of Metabolic and Developmental Sciences, 
      State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, 
      Shanghai Jiao Tong University, Shanghai 20040, China.
FAU - Wang, Chong
AU  - Wang C
AUID- ORCID: 0000-0001-9433-0112
AD  - Joint International Research Laboratory of Metabolic and Developmental Sciences, 
      State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, 
      Shanghai Jiao Tong University, Shanghai 20040, China.
FAU - Higgins, James D
AU  - Higgins JD
AUID- ORCID: 0000-0001-6027-8678
AD  - Department of Genetics and Genome Biology, University of Leicester, University 
      Road, Leicester LE1 7RH, United Kingdom.
FAU - Kim, Yu-Jin
AU  - Kim YJ
AD  - Graduate School of Biotechnology and Crop Biotech Institute, Kyung Hee 
      University, Yongin 17104, South Korea.
FAU - Moon, Sunok
AU  - Moon S
AUID- ORCID: 0000-0002-1659-5614
AD  - Graduate School of Biotechnology and Crop Biotech Institute, Kyung Hee 
      University, Yongin 17104, South Korea.
FAU - Jung, Ki-Hong
AU  - Jung KH
AUID- ORCID: 0000-0003-0427-5901
AD  - Graduate School of Biotechnology and Crop Biotech Institute, Kyung Hee 
      University, Yongin 17104, South Korea.
FAU - Qu, Shuying
AU  - Qu S
AUID- ORCID: 0000-0001-8841-2568
AD  - Joint International Research Laboratory of Metabolic and Developmental Sciences, 
      State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, 
      Shanghai Jiao Tong University, Shanghai 20040, China.
FAU - Liang, Wanqi
AU  - Liang W
AUID- ORCID: 0000-0002-9938-5793
AD  - Joint International Research Laboratory of Metabolic and Developmental Sciences, 
      State Key Laboratory of Hybrid Rice, School of Life Sciences and Biotechnology, 
      Shanghai Jiao Tong University, Shanghai 20040, China wqliang@sjtu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190702
PL  - United States
TA  - Plant Physiol
JT  - Plant physiology
JID - 0401224
RN  - 0 (Multiprotein Complexes)
RN  - 0 (Plant Proteins)
SB  - IM
MH  - Amino Acid Sequence
MH  - Chromosome Pairing/*genetics
MH  - Crossing Over, Genetic/*genetics
MH  - Multiprotein Complexes/genetics/*metabolism
MH  - Oryza/cytology/*genetics/metabolism
MH  - Plant Proteins/genetics/*metabolism
MH  - Sequence Alignment
MH  - Synaptonemal Complex/genetics/metabolism
PMC - PMC6716249
EDAT- 2019/07/04 06:00
MHDA- 2020/09/01 06:00
PMCR- 2019/07/02
CRDT- 2019/07/04 06:00
PHST- 2019/01/24 00:00 [received]
PHST- 2019/06/18 00:00 [accepted]
PHST- 2019/07/04 06:00 [pubmed]
PHST- 2020/09/01 06:00 [medline]
PHST- 2019/07/04 06:00 [entrez]
PHST- 2019/07/02 00:00 [pmc-release]
AID - pp.19.00082 [pii]
AID - 201900082R2 [pii]
AID - 10.1104/pp.19.00082 [doi]
PST - ppublish
SO  - Plant Physiol. 2019 Sep;181(1):221-235. doi: 10.1104/pp.19.00082. Epub 2019 Jul 
      2.