PMID- 31266911
OWN - NLM
STAT- MEDLINE
DCOM- 20190711
LR  - 20190711
IS  - 0021-5252 (Print)
IS  - 0021-5252 (Linking)
VI  - 72
IP  - 4
DP  - 2019 Apr
TI  - [Total Repair of Pulmonary Atresia, Ventricular Septal Defect, and Major 
      Aorto-pulmonary Collateral Arteries That were Deemed Unrepairable in an 
      Adolescent and Adults].
PG  - 263-268
AB  - Pulmonary atresia, ventricular septal defect, and major aorto-pulmonary 
      collateral arteries are deemed unrepairable in some patients. Reportedly, 39% to 
      63% of patients treated by the staged unifocalization pathway, and 25% to 51% of 
      patients treated by the pulmonary artery rehabilitation strategy were deemed 
      unsuitable to undergo total repair. Single-stage complete unifocalization with 
      intracardiac repair can be performed in some older patients with pulmonary 
      atresia, ventricular septal defect, and major aorto-pulmonary collateral arteries 
      that were previously deemed unrepairable. We report four such patients with ages 
      between 12 years and 28 years at surgery. Bosentan hydrate was administered 
      pre-operatively in one female patient for 14 months to ameliorate regional 
      pulmonary hypertension. Seventeen months after repair, she delivered a baby by 
      cesarean section. One patient underwent aortic valve replacement concomitant with 
      repair due to severe aortic regurgitation caused by healed infective 
      endocarditis. All patients were discharged home 9 to 18 days after surgery. After 
      72 to 100 months of follow-up, three patients are in New York Heart Association 
      (NYHA) class Ⅰ, and the remaining patient are in NYHA class Ⅱ. Single-stage 
      complete unifocalization can allow total repair in adolescents and adults with 
      pulmonary atresia, ventricular septal defect, and major aorto-pulmonary 
      collateral arteries that were previously deemed unrepairable.
FAU - Kaneko, Yukihiro
AU  - Kaneko Y
AD  - Division of Cardiovascular Surgery, National Medical Center for Children and 
      Mothers, Tokyo, Japan.
FAU - Achiwa, Ikuya
AU  - Achiwa I
FAU - Kondo, Ryouichi
AU  - Kondo R
FAU - Takei, Tetsuri
AU  - Takei T
LA  - jpn
PT  - Journal Article
PL  - Japan
TA  - Kyobu Geka
JT  - Kyobu geka. The Japanese journal of thoracic surgery
JID - 0413533
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cesarean Section
MH  - Child
MH  - Collateral Circulation
MH  - Female
MH  - *Heart Defects, Congenital/surgery
MH  - *Heart Septal Defects, Ventricular/surgery
MH  - Humans
MH  - Pregnancy
MH  - Pulmonary Artery
MH  - *Pulmonary Atresia/surgery
MH  - Young Adult
EDAT- 2019/07/04 06:00
MHDA- 2019/07/12 06:00
CRDT- 2019/07/04 06:00
PHST- 2019/07/04 06:00 [entrez]
PHST- 2019/07/04 06:00 [pubmed]
PHST- 2019/07/12 06:00 [medline]
PST - ppublish
SO  - Kyobu Geka. 2019 Apr;72(4):263-268.