PMID- 31275941
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231012
IS  - 2296-858X (Print)
IS  - 2296-858X (Electronic)
IS  - 2296-858X (Linking)
VI  - 6
DP  - 2019
TI  - Frailty and Intrinsic Capacity: Two Distinct but Related Constructs.
PG  - 133
LID - 10.3389/fmed.2019.00133 [doi]
LID - 133
AB  - Frailty is a clinical condition characterized by the individual's increased 
      vulnerability to endogenous and exogenous stressors. It is determined by the 
      reduction of homeostatic capacities of the organism and responsible for a marked 
      risk of adverse health outcomes (including functional loss and mortality). 
      Frailty originates from the geriatric background and may pave the way toward a 
      model of care centered on the person, deviating from the traditional and obsolete 
      disease-focused approach. Unfortunately, many controversies have affected the 
      field of frailty over the years and ambiguities have been growing. In particular, 
      the common use of frailty as condition to "exclude" from interventions is a 
      worrisome trend. In fact, the detection of frailty should instead represent the 
      entry point for a more in-depth analysis with the aim of identifying the causes 
      of individual's increased vulnerability and implementing a person-tailored 
      intervention plan. With the aim of promoting a more comprehensive and appropriate 
      assessment of the aging population, the World Health Organization introduced the 
      concept of intrinsic capacity (IC), defined as the composite of all physical and 
      mental capacities that an individual can draw upon during his/her life. Frailty 
      and IC are two constructs stemming from the same need of overcoming traditional 
      medical paradigms that negatively impact on the correct way clinical and research 
      practice should be conducted in older persons. In this article, we describe the 
      similarities and differences between the two constructs, highlighting how 
      geriatric medicine contributed to their development and will be crucial for their 
      further integration in future healthcare models.
FAU - Belloni, Giulia
AU  - Belloni G
AD  - Specialisation School in Geriatrics, University of Milan, Milan, Italy.
FAU - Cesari, Matteo
AU  - Cesari M
AD  - Department of Clinical Sciences and Community Health, University of Milan, Milan, 
      Italy.
AD  - Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20190618
PL  - Switzerland
TA  - Front Med (Lausanne)
JT  - Frontiers in medicine
JID - 101648047
PMC - PMC6591451
OTO - NOTNLM
OT  - comprehensive geriatric assessment
OT  - disability
OT  - healthy aging
OT  - older people
OT  - person-centered care
OT  - public health
EDAT- 2019/07/06 06:00
MHDA- 2019/07/06 06:01
PMCR- 2019/06/18
CRDT- 2019/07/06 06:00
PHST- 2019/03/26 00:00 [received]
PHST- 2019/05/30 00:00 [accepted]
PHST- 2019/07/06 06:00 [entrez]
PHST- 2019/07/06 06:00 [pubmed]
PHST- 2019/07/06 06:01 [medline]
PHST- 2019/06/18 00:00 [pmc-release]
AID - 10.3389/fmed.2019.00133 [doi]
PST - epublish
SO  - Front Med (Lausanne). 2019 Jun 18;6:133. doi: 10.3389/fmed.2019.00133. 
      eCollection 2019.