PMID- 31284335
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2586-6583 (Print)
IS  - 2586-6591 (Electronic)
IS  - 2586-6591 (Linking)
VI  - 16
IP  - 4
DP  - 2019 Dec
TI  - Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication 
      Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion.
PG  - 772-779
LID - 10.14245/ns.1938006.003 [doi]
AB  - OBJECTIVE: The relationship between bone graft technique and postoperative 
      outcomes for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) 
      has not been well-defined. This study aims to determine the effect of iliac crest 
      bone grafting (ICBG) on patient-reported outcomes (PROs) and complication rates 
      following MIS TLIF. METHODS: Primary, single-level MIS TLIF patients were 
      consecutively analyzed. Patients that prospectively received a percutaneous 
      technique of ICBG were compared to patients that retrospectively received bone 
      morphogenetic protein-2 (BMP-2). Complication rates were assessed perioperatively 
      and up to 1 year postoperatively. Changes in Oswestry Disability Index (ODI), 
      visual analogue scale (VAS) back, and VAS leg pain were compared. Rates of 
      minimum clinically important difference (MCID) achievement at final follow-up for 
      ODI, VAS back, and VAS leg scores were compared. RESULTS: One hundred forty-nine 
      patients were included: 101 in the BMP-2 cohort and 48 in the ICBG cohort. The 
      ICBG cohort demonstrated increases in intraoperative blood loss and shorter 
      lengths of stay. ICBG patients also experienced longer operative times, though 
      this did not reach statistical significance. No significant differences in 
      complication or reoperation rates were identified. The ICBG cohort demonstrated 
      greater improvements in VAS leg pain at 6-week and 12-week follow-up. No other 
      significant differences in PROs or MCID achievement rates were identified. 
      CONCLUSION: Patients undergoing MIS TLIF with ICBG experienced clinically 
      insignificant increases in intraoperative blood loss and did not experience 
      increases in postoperative pain or disability. Complication and reoperation rates 
      were similar between groups. These results suggest that ICBG is a safe option for 
      MIS TLIF.
FAU - Haws, Brittany E
AU  - Haws BE
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Khechen, Benjamin
AU  - Khechen B
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Patel, Dil V
AU  - Patel DV
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Yoo, Joon S
AU  - Yoo JS
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Guntin, Jordan A
AU  - Guntin JA
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Cardinal, Kaitlyn L
AU  - Cardinal KL
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Ahn, Junyoung
AU  - Ahn J
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20190708
PL  - Korea (South)
TA  - Neurospine
JT  - Neurospine
JID - 101724936
PMC - PMC6944998
OTO - NOTNLM
OT  - Bone morphogenic protein-2
OT  - Iliac crest bone graft
OT  - Minimally invasive transforaminal lumbar interbody fusion
OT  - Minimum clinically important difference
OT  - Oswestry Disability Index
OT  - Visual analogue scale
COIS- The authors have nothing to disclose.
EDAT- 2019/07/10 06:00
MHDA- 2019/07/10 06:01
PMCR- 2019/12/01
CRDT- 2019/07/09 06:00
PHST- 2019/01/04 00:00 [received]
PHST- 2019/05/07 00:00 [accepted]
PHST- 2019/07/10 06:00 [pubmed]
PHST- 2019/07/10 06:01 [medline]
PHST- 2019/07/09 06:00 [entrez]
PHST- 2019/12/01 00:00 [pmc-release]
AID - ns.1938006.003 [pii]
AID - ns-1938006-003 [pii]
AID - 10.14245/ns.1938006.003 [doi]
PST - ppublish
SO  - Neurospine. 2019 Dec;16(4):772-779. doi: 10.14245/ns.1938006.003. Epub 2019 Jul 
      8.