PMID- 31286808
OWN - NLM
STAT- MEDLINE
DCOM- 20191227
LR  - 20191227
IS  - 1651-226X (Electronic)
IS  - 0284-186X (Linking)
VI  - 58
IP  - 9
DP  - 2019 Sep
TI  - Survivors' knowledge of their diagnosis, treatment and possible late adverse 
      effects after autologous stem cell transplantation for lymphoma.
PG  - 1315-1322
LID - 10.1080/0284186X.2019.1637538 [doi]
AB  - Purpose: Lymphoma survivors after high dose therapy with autologous stem cell 
      therapy (HD-ASCT) are at high risk for late adverse effects (AEs). Information 
      patients receive and collect throughout their cancer trajectory about diagnosis, 
      treatment schedule and risks of AEs may influence attitudes and health-related 
      behavior in the years after treatment. The purpose of this study was to explore 
      level of knowledge in lymphoma survivors after HD-ASCT at a median of 12 years 
      after primary diagnosis. Material and methods: From a national study on the 
      effects of HD-ASCT for lymphomas, 269 survivors met for an outpatient 
      examination, including a structured interview addressing knowledge about 
      diagnosis and treatment. Survivors were also asked whether they knew and/or had 
      experienced certain common late AEs. Numbers of recognized and experienced late 
      AEs were presented as sum scores. Factors associated with the level of knowledge 
      of late AEs were analyzed by linear regression analysis. Results: Eighty-one 
      percent of the survivors knew their diagnosis, 99% knew the components of HD-ASCT 
      and 97% correctly recalled having had radiotherapy. Ninety percent reported 
      awareness of late AEs, but the level of knowledge and personal experience with 
      specified AEs varied. Thirty-five percent of survivors stated to have received 
      follow-up for late AEs. In multivariable analysis younger age at diagnosis, 
      having received mediastinal radiotherapy, higher mental health related quality of 
      life, a higher number of self-experienced late AEs and having received follow-up 
      care for late AEs were significantly associated with a higher level of knowledge 
      of AEs. Conclusion: The majority of lymphoma survivors treated with HD-ASCT 
      correctly recalled diagnosis and treatment, while knowledge of late AEs varied. 
      Our findings point to information deficits in survivors at older age and with 
      lower mental health related quality of life. They indicate benefit of follow-up 
      to enhance education on late AEs in lymphoma survivors.
FAU - Simensen, Victoria C
AU  - Simensen VC
AD  - National Advisory Unit for Late Effects after Cancer Treatment, Oslo University 
      Hospital , Oslo, Norway.
AD  - Department of Oncology, Oslo University Hospital , Oslo, Norway.
FAU - Smeland, Knut B
AU  - Smeland KB
AD  - National Advisory Unit for Late Effects after Cancer Treatment, Oslo University 
      Hospital , Oslo, Norway.
AD  - Department of Oncology, Oslo University Hospital , Oslo, Norway.
FAU - Kiserud, Cecilie E
AU  - Kiserud CE
AD  - National Advisory Unit for Late Effects after Cancer Treatment, Oslo University 
      Hospital , Oslo, Norway.
AD  - Department of Oncology, Oslo University Hospital , Oslo, Norway.
FAU - Dahl, Alv A
AU  - Dahl AA
AD  - National Advisory Unit for Late Effects after Cancer Treatment, Oslo University 
      Hospital , Oslo, Norway.
AD  - Faculty of Medicine, University of Oslo , Oslo , Norway.
FAU - Bersvendsen, Hanne S
AU  - Bersvendsen HS
AD  - Department of Oncology, University Hospital of North Norway , Tromso , Norway.
FAU - Fluge, Oystein
AU  - Fluge O
AD  - Department of Oncology, Haukeland University Hospital , Bergen , Norway.
FAU - Fagerli, Unn-Merete
AU  - Fagerli UM
AD  - Department of Oncology, St. Olav's University Hospital , Trondheim , Norway.
AD  - Institute Clinical and Molecular Medicine (IKOM), The Norwegian University of 
      Science and Technology (NTNU) , Trondheim , Norway.
FAU - Fossa, Alexander
AU  - Fossa A
AD  - National Advisory Unit for Late Effects after Cancer Treatment, Oslo University 
      Hospital , Oslo, Norway.
AD  - Department of Oncology, Oslo University Hospital , Oslo, Norway.
LA  - eng
PT  - Journal Article
DEP - 20190709
PL  - Sweden
TA  - Acta Oncol
JT  - Acta oncologica (Stockholm, Sweden)
JID - 8709065
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Cancer Survivors/*psychology/statistics & numerical data
MH  - Child
MH  - Female
MH  - Health Behavior
MH  - *Health Knowledge, Attitudes, Practice
MH  - Hematopoietic Stem Cell Transplantation/*adverse effects/methods
MH  - Humans
MH  - Lymphoma/diagnosis/*psychology/radiotherapy/surgery
MH  - Male
MH  - Mental Recall
MH  - Middle Aged
MH  - Norway
MH  - Patient Education as Topic
MH  - Quality of Life
MH  - Regression Analysis
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - Transplantation Conditioning/methods/statistics & numerical data
MH  - Transplantation, Autologous/adverse effects
MH  - Young Adult
EDAT- 2019/07/10 06:00
MHDA- 2019/12/28 06:00
CRDT- 2019/07/10 06:00
PHST- 2019/07/10 06:00 [pubmed]
PHST- 2019/12/28 06:00 [medline]
PHST- 2019/07/10 06:00 [entrez]
AID - 10.1080/0284186X.2019.1637538 [doi]
PST - ppublish
SO  - Acta Oncol. 2019 Sep;58(9):1315-1322. doi: 10.1080/0284186X.2019.1637538. Epub 
      2019 Jul 9.