PMID- 31286869
OWN - NLM
STAT- MEDLINE
DCOM- 20190723
LR  - 20200225
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 19
IP  - 1
DP  - 2019 Jul 8
TI  - Comparison of spectral domain and swept source optical coherence tomography for 
      angle assessment of Chinese elderly subjects.
PG  - 142
LID - 10.1186/s12886-019-1145-7 [doi]
LID - 142
AB  - BACKGROUND: This comparative study aimed to demonstrate the differences between 
      swept source OCT (SS-OCT) (1310 nm) and spectral domain OCT (SD-OCT) (840 nm) for 
      the identification and measurement of anterior chamber angle (ACA) structures. 
      METHODS: Sixty seven eyes from 67 healthy subjects underwent ACA imaging at the 
      nasal and temporal sides using SS-OCT and SD-OCT with different wavelength 
      (Tomey, 1310 nm and RTvue, 840 nm). Images were evaluated for the ability to 
      distinguish angle structures including the Schwalbe's line (SL), the Schlemm's 
      canal (SC) and the scleral spur (SS). The length of trabecular meshwork (LTM), 
      the angle-opening distance (AOD500 and AOD750) and the length of Schlemm's canal 
      (LSC) were also measured. RESULTS: The nasal identification rate for SL, SC and 
      SS were 91.04%/89.55%, 50.75%/40.30% and 100.0%/74.63% (SS-OCT/SD-OCT), 
      respectively. The temporal identification rate for SL, SC and SS were 
      86.57%/91.04%, 68.66%/70.15% and 100.0%/65.67% (SS-OCT/SD-OCT), respectively. 
      Differences between SS-OCT and SD-OCT were found in terms of the visualization of 
      the SS. With respect to the measurements of angle, the evaluation of LTM at the 
      nasal side, LSC at the temporal side and AOD500/750 at both sides showed 
      significant difference between the two devices. However, there existed good 
      correlation between the AOD500/750 measured by SS-OCT and SD-OCT (Spearman's rank 
      correlation coefficient > 0.8, p < 0.000). CONCLUSIONS: SS-OCT displayed a better 
      performance in detecting deeper structures of the angle such as the SS. However, 
      for discriminating structures lying in transparent or semi-transparent tissue 
      such as the SL and the SC, the two devices showed good consistency. Although 
      SS-OCT and SD-OCT demonstrated high correlation for angle measurement 
      (AOD500/750), their agreement was poor.
FAU - Qiao, Yunsheng
AU  - Qiao Y
AD  - Department of Ophthalmology & Visual Science, Eye and ENT Hospital of Fudan 
      University, 83 Fenyang Rd, Shanghai, 200031, China.
FAU - Tan, Chen
AU  - Tan C
AD  - Department of Ophthalmology & Visual Science, Eye and ENT Hospital of Fudan 
      University, 83 Fenyang Rd, Shanghai, 200031, China.
FAU - Zhang, Min
AU  - Zhang M
AD  - Department of Ophthalmology & Visual Science, Eye and ENT Hospital of Fudan 
      University, 83 Fenyang Rd, Shanghai, 200031, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences and Key Laboratory of Visual Impairment and 
      Restoration of Shanghai, Shanghai, 200031, China.
FAU - Sun, Xinghuai
AU  - Sun X
AD  - Department of Ophthalmology & Visual Science, Eye and ENT Hospital of Fudan 
      University, 83 Fenyang Rd, Shanghai, 200031, China.
AD  - State Key Laboratory of Medical Neurobiology, Institutes of Brain Science and 
      Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, 
      200032, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences and Key Laboratory of Visual Impairment and 
      Restoration of Shanghai, Shanghai, 200031, China.
FAU - Chen, Junyi
AU  - Chen J
AD  - Department of Ophthalmology & Visual Science, Eye and ENT Hospital of Fudan 
      University, 83 Fenyang Rd, Shanghai, 200031, China. chenjy@fudan.edu.cn.
LA  - eng
GR  - 81470623/National Natural Science Foundation of China/
GR  - 81870661/National Natural Science Foundation of China/
PT  - Comparative Study
PT  - Journal Article
DEP - 20190708
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
MH  - Anterior Eye Segment/*diagnostic imaging
MH  - China/epidemiology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Glaucoma, Angle-Closure/*diagnosis/epidemiology/physiopathology
MH  - Glaucoma, Open-Angle/*diagnosis/physiopathology
MH  - Gonioscopy
MH  - Healthy Volunteers
MH  - Humans
MH  - Incidence
MH  - Intraocular Pressure/*physiology
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
MH  - Trabecular Meshwork/diagnostic imaging
PMC - PMC6615428
OTO - NOTNLM
OT  - Angle
OT  - Optical coherence tomography
OT  - Spectral domain
OT  - Swept source
OT  - Wavelength
COIS- The authors declare that they no competing interests.
EDAT- 2019/07/10 06:00
MHDA- 2019/07/25 06:00
PMCR- 2019/07/08
CRDT- 2019/07/10 06:00
PHST- 2019/04/09 00:00 [received]
PHST- 2019/06/13 00:00 [accepted]
PHST- 2019/07/10 06:00 [entrez]
PHST- 2019/07/10 06:00 [pubmed]
PHST- 2019/07/25 06:00 [medline]
PHST- 2019/07/08 00:00 [pmc-release]
AID - 10.1186/s12886-019-1145-7 [pii]
AID - 1145 [pii]
AID - 10.1186/s12886-019-1145-7 [doi]
PST - epublish
SO  - BMC Ophthalmol. 2019 Jul 8;19(1):142. doi: 10.1186/s12886-019-1145-7.