PMID- 31287954
OWN - NLM
STAT- MEDLINE
DCOM- 20200923
LR  - 20200923
IS  - 1520-5126 (Electronic)
IS  - 0002-7863 (Linking)
VI  - 141
IP  - 30
DP  - 2019 Jul 31
TI  - Self-Healing Hyper-Cross-Linked Metal-Organic Polyhedra (HCMOPs) Membranes with 
      Antimicrobial Activity and Highly Selective Separation Properties.
PG  - 12064-12070
LID - 10.1021/jacs.9b05155 [doi]
AB  - Fabrication of hybrid membranes composed of porous materials embedded in polymer 
      matrices is a subject of topical interest. Herein, we introduce a new class of 
      hybrid membranes: hyper-cross-linked metal-organic polyhedra (HCMOPs). These 
      membranes are based upon soluble MOPs that can serve as high-connectivity nodes 
      in hyper-cross-linked polymer networks. HCMOPs spontaneously form macro-scale, 
      defect-free, freestanding membranes, and, thanks to the covalent cross-linking of 
      MOPs, the resulting membranes possess multiple functionalities: strong water 
      permeability; self-healing ability; antimicrobial activity; and better separation 
      and mechanical performance than pristine polyimine membranes. This study 
      introduces a new concept for the design and fabrication of multifunctional 
      membranes and also broadens the applications of MOPs.
FAU - Liu, Jinjin
AU  - Liu J
AD  - College of Chemistry , Nankai University , Tianjin 300071 , P. R. China.
FAU - Duan, Wenjie
AU  - Duan W
AD  - State Key Laboratory of Medicinal Chemical biology , Nankai University , Tianjin 
      300071 , P. R. China.
AD  - College of Pharmacy , Nankai University , Tianjin 300071 , P. R. China.
FAU - Song, Jie
AU  - Song J
AD  - State Key Laboratory of Medicinal Chemical biology , Nankai University , Tianjin 
      300071 , P. R. China.
AD  - College of Pharmacy , Nankai University , Tianjin 300071 , P. R. China.
FAU - Guo, Xiuxiu
AU  - Guo X
AD  - College of Chemistry , Nankai University , Tianjin 300071 , P. R. China.
FAU - Wang, Zhifang
AU  - Wang Z
AD  - College of Chemistry , Nankai University , Tianjin 300071 , P. R. China.
FAU - Shi, Xinlei
AU  - Shi X
AD  - School of Materials Science and Engineering , Nankai University , Tianjin 300071 
      , P. R. China.
FAU - Liang, Jiajie
AU  - Liang J
AUID- ORCID: 0000-0003-2112-6721
AD  - School of Materials Science and Engineering , Nankai University , Tianjin 300071 
      , P. R. China.
FAU - Wang, Juan
AU  - Wang J
AD  - College of Chemistry , Nankai University , Tianjin 300071 , P. R. China.
FAU - Cheng, Peng
AU  - Cheng P
AUID- ORCID: 0000-0003-0396-1846
AD  - College of Chemistry , Nankai University , Tianjin 300071 , P. R. China.
FAU - Chen, Yao
AU  - Chen Y
AUID- ORCID: 0000-0002-3465-7380
AD  - State Key Laboratory of Medicinal Chemical biology , Nankai University , Tianjin 
      300071 , P. R. China.
AD  - College of Pharmacy , Nankai University , Tianjin 300071 , P. R. China.
FAU - Zaworotko, Michael J
AU  - Zaworotko MJ
AUID- ORCID: 0000-0002-1360-540X
AD  - Department of Chemical Sciences , Bernal Institute University of Limerick , 
      Limerick V94T9PX , Republic of Ireland.
FAU - Zhang, Zhenjie
AU  - Zhang Z
AUID- ORCID: 0000-0003-2053-3771
AD  - College of Chemistry , Nankai University , Tianjin 300071 , P. R. China.
AD  - State Key Laboratory of Medicinal Chemical biology , Nankai University , Tianjin 
      300071 , P. R. China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20190718
PL  - United States
TA  - J Am Chem Soc
JT  - Journal of the American Chemical Society
JID - 7503056
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Antifungal Agents)
RN  - 0 (Imines)
RN  - 0 (Metal-Organic Frameworks)
RN  - 0 (Polymers)
SB  - IM
MH  - Anti-Bacterial Agents/chemistry/*pharmacology
MH  - Antifungal Agents/chemistry/*pharmacology
MH  - Cryptococcus neoformans/drug effects
MH  - Dose-Response Relationship, Drug
MH  - Escherichia coli/drug effects
MH  - Imines/chemistry/*pharmacology
MH  - Metal-Organic Frameworks/chemistry/*pharmacology
MH  - Microbial Sensitivity Tests
MH  - Polymers/chemistry/*pharmacology
MH  - Saccharomyces cerevisiae/drug effects
MH  - Staphylococcus aureus/drug effects
EDAT- 2019/07/10 06:00
MHDA- 2020/09/24 06:00
CRDT- 2019/07/10 06:00
PHST- 2019/07/10 06:00 [pubmed]
PHST- 2020/09/24 06:00 [medline]
PHST- 2019/07/10 06:00 [entrez]
AID - 10.1021/jacs.9b05155 [doi]
PST - ppublish
SO  - J Am Chem Soc. 2019 Jul 31;141(30):12064-12070. doi: 10.1021/jacs.9b05155. Epub 
      2019 Jul 18.