PMID- 31290920 OWN - NLM STAT- MEDLINE DCOM- 20191211 LR - 20191217 IS - 1940-3372 (Electronic) IS - 1940-3372 (Linking) VI - 12 IP - 2 DP - 2019 Jun TI - Genomic Prediction of Pumpkin Hybrid Performance. LID - 10.3835/plantgenome2018.10.0082 [doi] AB - Genomic prediction has become an increasingly popular tool for hybrid performance evaluation in plant breeding mainly because that it can reduce cost and accelerate a breeding program. In this study, we propose a systematic procedure to predict hybrid performance using a genomic selection (GS) model that takes both additive and dominance marker effects into account. We first demonstrate the advantage of the additive-dominance effects model over the only additive effects model through a simulation study. Based on the additive-dominance model, we predict genomic estimated breeding values (GEBVs) for individual hybrid combinations and their parental lines. The GEBV-based specific combining ability (SCA) for each hybrid and general combining ability (GCA) for its parental lines are then derived to quantify the degree of midparent heterosis (MPH) or better-parent heterosis (BPH) of the hybrid. Finally, we estimate the variance components resulting from additive and dominance gene action effects and heritability using a genomic best linear unbiased predictor (g-BLUP) model. These estimates are used to justify the results of the genomic prediction study. A pumpkin ( spp.) data set is given to illustrate the provided procedure. The data set consists of 320 parental lines with 61,179 collected single nucleotide polymorphism (SNP) markers; 119, 120, and 120 phenotypic values of hybrids on three quantitative traits within maxima Duchesne; and 89, 111, and 90 phenotypic values of hybrids on the same three quantitative traits within Dechesne. CI - (c) 2019 The Author(s). FAU - Wu, Po-Ya AU - Wu PY FAU - Tung, Chih-Wei AU - Tung CW FAU - Lee, Chieh-Ying AU - Lee CY FAU - Liao, Chen-Tuo AU - Liao CT LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Plant Genome JT - The plant genome JID - 101273919 SB - IM MH - Bayes Theorem MH - Computer Simulation MH - Cucurbita/genetics/*physiology MH - Datasets as Topic MH - Genetic Variation MH - *Hybridization, Genetic MH - Inheritance Patterns MH - Models, Genetic MH - Models, Statistical MH - *Plant Breeding MH - Selection, Genetic EDAT- 2019/07/11 06:00 MHDA- 2019/12/18 06:00 CRDT- 2019/07/11 06:00 PHST- 2019/07/11 06:00 [entrez] PHST- 2019/07/11 06:00 [pubmed] PHST- 2019/12/18 06:00 [medline] AID - 10.3835/plantgenome2018.10.0082 [doi] PST - ppublish SO - Plant Genome. 2019 Jun;12(2). doi: 10.3835/plantgenome2018.10.0082.