PMID- 31301901
OWN - NLM
STAT- MEDLINE
DCOM- 20200622
LR  - 20200622
IS  - 1097-685X (Electronic)
IS  - 0022-5223 (Linking)
VI  - 159
IP  - 5
DP  - 2020 May
TI  - Serial cardiac magnetic resonance imaging after surgical coronary 
      revascularization for left ventricular dysfunction.
PG  - 1798-1805
LID - S0022-5223(19)31165-1 [pii]
LID - 10.1016/j.jtcvs.2019.04.109 [doi]
AB  - OBJECTIVES: Serial changes in segmental myocardial function after surgical 
      myocardial revascularization have not been well demonstrated. This study was 
      conducted to evaluate improvements in segmental myocardial function after 
      coronary artery bypass grafting in patients with left ventricular dysfunction. 
      METHODS: Serial cardiac magnetic resonance with late gadolinium enhancement (LGE) 
      was performed in 67 patients with left ventricular ejection fraction </=0.35, 
      preoperatively and at 3 months and 1 year after surgery. The wall motion score 
      and transmural extent of LGE were evaluated on a 16-segment model. Changes in 
      segmental myocardial function were evaluated according to the transmurality of 
      LGE (5-point scale: grade 0 = absence of LGE, 1 = LGE 1%-25%, 2 = LGE 26%-50%, 
      3 = LGE 51%-75%, and 4 = LGE 76%-100%). RESULTS: Of 908 segments in which 1-year 
      graft patency was confirmed, 657 dysfunctional segments (378 hypokinesia, 275 
      akinesia, 2 dyskinesia, and 2 aneurysm) were evaluated. The LGE grades were 0, 1, 
      2, 3, and 4 in 235, 187, 127, 59, and 49 segments, respectively. Segmental 
      myocardial function improved in 56.5% (371 out of 657 segments) and 58.9% (387 
      out of 657 segments) of dysfunctional segments at 3 months and 1 year, 
      respectively. Of LGE grades 0, 1, 2, 3, and 4 segments, improved wall motion was 
      observed with an inverse correlation in 71.1% (167 out of 235 segments), 55.1% 
      (103 out of 187 segments), 49.6% (63 out of 127 segments), 40.7% (24 out of 59 
      segments), and 28.6% (14 out of 49 segments) at 3 months and in 74.0% (174 out of 
      235 segments), 57.2% (107 out of 187 segments), 52.8% (67 out of 127 segments), 
      44.1% (26 out of 59 segments), and 26.5% (13 out of 49 segments) at 1 year, 
      respectively. CONCLUSIONS: One third of segments with a transmural extent of LGE 
      >50% still had a chance for improvement after revascularization, although an 
      inverse correlation was seen between the LGE grade and improvement of segmental 
      myocardial function.
CI  - Copyright (c) 2019 The American Association for Thoracic Surgery. Published by 
      Elsevier Inc. All rights reserved.
FAU - Hwang, Ho Young
AU  - Hwang HY
AD  - Department of Thoracic and Cardiovascular Surgery, Seoul National University 
      Hospital, Seoul, Korea.
FAU - Yeom, Sang Yoon
AU  - Yeom SY
AD  - Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, 
      Bucheon, Korea.
FAU - Park, Eun-Ah
AU  - Park EA
AD  - Department of Radiology, Seoul National University Hospital, Seoul, Korea.
FAU - Lee, Whal
AU  - Lee W
AD  - Department of Radiology, Seoul National University Hospital, Seoul, Korea.
FAU - Jang, Myoung-Jin
AU  - Jang MJ
AD  - Medical Research Collaborating Center, Seoul National University Hospital, Seoul, 
      Korea.
FAU - Kim, Ki-Bong
AU  - Kim KB
AD  - Department of Thoracic and Cardiovascular Surgery, Seoul National University 
      Hospital, Seoul, Korea. Electronic address: kimkb@snu.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Video-Audio Media
DEP - 20190608
PL  - United States
TA  - J Thorac Cardiovasc Surg
JT  - The Journal of thoracic and cardiovascular surgery
JID - 0376343
SB  - IM
CIN - J Thorac Cardiovasc Surg. 2020 May;159(5):1806. PMID: 31230812
CIN - J Thorac Cardiovasc Surg. 2020 May;159(5):1807-1808. PMID: 31669008
MH  - Aged
MH  - *Coronary Artery Bypass/adverse effects
MH  - Coronary Artery Disease/diagnostic imaging/physiopathology/*surgery
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - *Stroke Volume
MH  - Time Factors
MH  - Treatment Outcome
MH  - Vascular Patency
MH  - Ventricular Dysfunction, Left/*diagnostic imaging/physiopathology
MH  - *Ventricular Function, Left
OTO - NOTNLM
OT  - cardiac magnetic resonance imaging
OT  - coronary artery bypass grafting
OT  - left ventricular dysfunction
EDAT- 2019/07/16 06:00
MHDA- 2020/06/23 06:00
CRDT- 2019/07/15 06:00
PHST- 2018/12/04 00:00 [received]
PHST- 2019/04/11 00:00 [revised]
PHST- 2019/04/27 00:00 [accepted]
PHST- 2019/07/16 06:00 [pubmed]
PHST- 2020/06/23 06:00 [medline]
PHST- 2019/07/15 06:00 [entrez]
AID - S0022-5223(19)31165-1 [pii]
AID - 10.1016/j.jtcvs.2019.04.109 [doi]
PST - ppublish
SO  - J Thorac Cardiovasc Surg. 2020 May;159(5):1798-1805. doi: 
      10.1016/j.jtcvs.2019.04.109. Epub 2019 Jun 8.