PMID- 31303625 OWN - NLM STAT- MEDLINE DCOM- 20190718 LR - 20190718 IS - 1672-7347 (Print) IS - 1672-7347 (Linking) VI - 44 IP - 5 DP - 2019 May 28 TI - [A case of nephrectomy with strong positive HLA antibody undergoing the third renal transplantation]. PG - 596-599 LID - 10.11817/j.issn.1672-7347.2019.05.018 [doi] AB - The positive human leukocyte antigen (HLA) antibody present in kidney transplant recipients affects both surgery and rejection, and also affects the long-term survival of the transplanted kidney. During the third kidney transplant, bilateral axillary fossa and iliac vessel were destroyed. It was very difficult for selection or separation of surgical vessels because the adhesions and scar formation was easy to damage blood vessels and intestinal tubes. A case with strong positive HLA antibody undergoing the third kidney transplant in our hospital was successfully solved the problems, such as less transplant space and vascular scar adhesion. Rituximab, rabbit anti-human thymocyte immunoglobulin, and methylprednisolone treated-antibodies were used in the operation. The immune function test was used to develop individualized treatment after the operation. The postoperative creatinine and urine volume tended to be stable, and the 16-month follow-up renal function was good. FAU - Deng, Pan AU - Deng P AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. FAU - Zhang, Sheng AU - Zhang S AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. FAU - Ming, Yingzi AU - Ming Y AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. FAU - Cheng, Ke AU - Cheng K AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. FAU - Wang, Qiang AU - Wang Q AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. FAU - Ye, Qifa AU - Ye Q AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. FAU - Zhao, Yujun AU - Zhao Y AD - Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. LA - chi PT - Case Reports PT - Journal Article PL - China TA - Zhong Nan Da Xue Xue Bao Yi Xue Ban JT - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences JID - 101230586 RN - 0 (Antibodies) RN - 4F4X42SYQ6 (Rituximab) SB - IM MH - Antibodies MH - Humans MH - Kidney MH - Kidney Diseases/*surgery MH - *Kidney Transplantation MH - Nephrectomy MH - Rituximab EDAT- 2019/07/16 06:00 MHDA- 2019/07/19 06:00 CRDT- 2019/07/16 06:00 PHST- 2019/07/16 06:00 [entrez] PHST- 2019/07/16 06:00 [pubmed] PHST- 2019/07/19 06:00 [medline] AID - 10.11817/j.issn.1672-7347.2019.05.018 [doi] PST - ppublish SO - Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 May 28;44(5):596-599. doi: 10.11817/j.issn.1672-7347.2019.05.018.