PMID- 31307636
OWN - NLM
STAT- MEDLINE
DCOM- 20191125
LR  - 20191125
IS  - 1872-7727 (Electronic)
IS  - 0720-048X (Linking)
VI  - 117
DP  - 2019 Aug
TI  - Tumour volume comparison between 16-row multi-detector computed tomography and 
      320-row area-detector computed tomography in patients with small lung tumours 
      treated with stereotactic body radiotherapy: Effect of respiratory motion.
PG  - 120-125
LID - S0720-048X(19)30206-2 [pii]
LID - 10.1016/j.ejrad.2019.06.002 [doi]
AB  - PURPOSE: We compared image quality and volume of a moving simulated tumour and of 
      lung tumours in patients who were treated with stereotactic body radiotherapy 
      (SBRT) in a 16-row multi-detector CT (MDCT) versus a 320-row area-detector CT 
      (ADCT). Tumour volumes in each respiratory phase were also evaluated. MATERIALS 
      AND METHODS: We acquired static and four-dimensional CT (4DCT) images of a moving 
      phantom with 10- and 30-mm amplitudes with three periods of patterns (2, 4, and 
      6 s). Breath-hold and 4DCT images were acquired for 12 lung tumour patients who 
      underwent SBRT. Image data were acquired via MDCT and ADCT. The tumours were 
      delineated in each respiratory phase and their volumes in 
      end-expiratory/end-inspiratory phase and mid-respiratory phase were compared. 
      RESULTS: In the phantom study, tumour volumes were smaller and closer to the 
      static image when evaluated by ADCT than by MDCT. In the clinical study, average 
      tumour volumes +/- standard deviations were 9.58 +/- 1.07 cm(3) with MDCT (2.5-mm 
      slice), and 7.12 +/- 0.23 cm(3) with ADCT (p < 0.01). Tumour volumes were closer to 
      that of the breath hold CT in all patients evaluated by ADCT than by MDCT. Unlike 
      MDCT, tumour volumes acquired by ADCT were smaller in end-expiratory or 
      end-inspiratory phase than in the mid-respiratory phase. CONCLUSIONS: Tumour 
      volumes in each of the respiratory phases in ADCT were significantly smaller and 
      closer to the static image than the corresponding volumes in MDCT. This suggests 
      that treated volume can be reduced if ADCT is used in treatment planning.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Iizuka, Yusuke
AU  - Iizuka Y
AD  - Department of Radiation Oncology and Image-applied Therapy, Graduate School of 
      Medicine, Kyoto University, Kyoto, Japan. Electronic address: 
      yiizuka@kuhp.kyoto-u.ac.jp.
FAU - Nakamura, Mitsuhiro
AU  - Nakamura M
AD  - Department of Radiation Oncology and Image-applied Therapy, Graduate School of 
      Medicine, Kyoto University, Kyoto, Japan.
FAU - Kozawa, Satoshi
AU  - Kozawa S
AD  - Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto, Japan.
FAU - Mitsuyoshi, Takamasa
AU  - Mitsuyoshi T
AD  - Department of Radiation Oncology and Image-applied Therapy, Graduate School of 
      Medicine, Kyoto University, Kyoto, Japan.
FAU - Matsuo, Yukinori
AU  - Matsuo Y
AD  - Department of Radiation Oncology and Image-applied Therapy, Graduate School of 
      Medicine, Kyoto University, Kyoto, Japan.
FAU - Mizowaki, Takashi
AU  - Mizowaki T
AD  - Department of Radiation Oncology and Image-applied Therapy, Graduate School of 
      Medicine, Kyoto University, Kyoto, Japan.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20190608
PL  - Ireland
TA  - Eur J Radiol
JT  - European journal of radiology
JID - 8106411
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - *Four-Dimensional Computed Tomography
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Lung Neoplasms/*diagnostic imaging/physiopathology/radiotherapy
MH  - Male
MH  - *Multidetector Computed Tomography
MH  - Phantoms, Imaging
MH  - Radiosurgery
MH  - Respiration
OTO - NOTNLM
OT  - Computed tomography
OT  - Multi-detector CT
OT  - Oncology
OT  - Stereotactic body radiotherapy
EDAT- 2019/07/17 06:00
MHDA- 2019/11/26 06:00
CRDT- 2019/07/17 06:00
PHST- 2019/01/01 00:00 [received]
PHST- 2019/05/18 00:00 [revised]
PHST- 2019/06/07 00:00 [accepted]
PHST- 2019/07/17 06:00 [entrez]
PHST- 2019/07/17 06:00 [pubmed]
PHST- 2019/11/26 06:00 [medline]
AID - S0720-048X(19)30206-2 [pii]
AID - 10.1016/j.ejrad.2019.06.002 [doi]
PST - ppublish
SO  - Eur J Radiol. 2019 Aug;117:120-125. doi: 10.1016/j.ejrad.2019.06.002. Epub 2019 
      Jun 8.