PMID- 31308957
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220409
IS  - 2055-1169 (Electronic)
IS  - 2055-1169 (Linking)
VI  - 5
IP  - 2
DP  - 2019 Jul-Dec
TI  - Percutaneous ultrasound-guided ethanol ablation for treatment of primary 
      hyperparathyroidism in a cat.
PG  - 2055116919860276
LID - 10.1177/2055116919860276 [doi]
LID - 2055116919860276
AB  - CASE SUMMARY: A 9-year-old male neutered European Shorthair cat was presented 
      owing to vomiting and mild weight loss. Clinical examination was normal, but 
      biochemistry results showed increased concentrations of total calcium (4.05 
      mmol/l; reference interval [RI] 2.20-2.90 mmol/l) and ionised calcium (iCa) (2.19 
      mmol/l; RI 1.12-1.40 mmol/l), as well as hypophosphataemia (2.5 mg/dl; RI 3.1-7.5 
      mg/dl). Parathyroid hormone (PTH) concentration (>1000 pg/ml) was markedly 
      increased, while parathyroid hormone-related protein concentration (<0.8 pmol/l) 
      was normal. Neck ultrasound showed a large left parathyroid mass (13 x 7 x 6 mm). 
      Under general anaesthesia and with ultrasonographic guidance, a fine-needle 
      aspiration of the mass followed by chemical ablation with 2 ml 96% ethanol was 
      performed. The cat was re-evaluated and iCa concentration measured 24 h, 72 h, 5 
      days, 4 weeks and 4 months post-ablation. Normocalcaemia was reached within 24 h, 
      remained stable throughout the whole evaluation period and the concentration of 
      PTH normalised 4 months later. Vomiting stopped promptly after chemical ablation 
      and a slight change in voice, as well as a mild prolapse of the nictitating 
      membrane, were the only side effects after the treatment but resolved some weeks 
      later. RELEVANCE AND NOVEL INFORMATION: To our knowledge, this is the first 
      report of successful chemical ablation of a parathyroid mass in a cat with 
      primary hyperparathyroidism. Chemical ablation might therefore be a possible 
      alternative to parathyroidectomy in cats.
FAU - Riehl, Valentina
AU  - Riehl V
AD  - Veterinary Clinic Hofheim, Hofheim am Taunus, Germany.
FAU - Hartmann, Antje
AU  - Hartmann A
AD  - Veterinary Clinic Hofheim, Hofheim am Taunus, Germany.
FAU - Rohrberg, Antje
AU  - Rohrberg A
AD  - Veterinary Clinic Hofheim, Hofheim am Taunus, Germany.
FAU - Neiger, Reto
AU  - Neiger R
AD  - Veterinary Clinic Hofheim, Hofheim am Taunus, Germany.
LA  - eng
PT  - Case Reports
DEP - 20190701
PL  - England
TA  - JFMS Open Rep
JT  - JFMS open reports
JID - 101672978
PMC - PMC6607573
OTO - NOTNLM
OT  - Hypercalcaemia
OT  - PHPT
OT  - endocrine
OT  - parathyroid
COIS- Conflict of interest: The authors declared no potential conflicts of interest 
      with respect to the research, authorship, and/or publication of this article.
EDAT- 2019/07/17 06:00
MHDA- 2019/07/17 06:01
PMCR- 2019/07/01
CRDT- 2019/07/17 06:00
PHST- 2019/07/17 06:00 [entrez]
PHST- 2019/07/17 06:00 [pubmed]
PHST- 2019/07/17 06:01 [medline]
PHST- 2019/07/01 00:00 [pmc-release]
AID - 10.1177_2055116919860276 [pii]
AID - 10.1177/2055116919860276 [doi]
PST - epublish
SO  - JFMS Open Rep. 2019 Jul 1;5(2):2055116919860276. doi: 10.1177/2055116919860276. 
      eCollection 2019 Jul-Dec.