PMID- 31312562
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 11
IP  - 5
DP  - 2019 May 10
TI  - A Case Report of Human Herpesvirus-6 (HHV-6) Meningitis Masquerading as 
      Idiopathic Intracranial Hypertension in an Immunocompetent Patient.
PG  - e4636
LID - 10.7759/cureus.4636 [doi]
LID - e4636
AB  - We present a case of a 32-year-old woman with signs and symptoms of idiopathic 
      intracranial hypertension (IIH), but who, upon further investigation, was found 
      to have human herpesvirus-6 (HHV-6) in both cerebrospinal fluid (CSF) and serum. 
      This rare cause of meningitis in an immunocompetent individual and a relatively 
      unique presentation is described along with a review of proper diagnostic workup 
      and treatment. HHV-6 meningitis is commonly detected via molecular 
      diagnostics and thus needs confirmatory testing of viral load of acellular 
      compartments or viral serology. The reason for this added diagnostic step is due 
      to the incorporation of the virus into the host DNA, leading to increased 
      false-positive results on screening tests. In this case, proper diagnosis, 
      treatment, and follow-up were pursued by following guidelines proposed in the 
      literature of HHV-6 meningitis.
FAU - Smith, Hayden Z
AU  - Smith HZ
AD  - Infectious Diseases, Creighton University Medical Center, Omaha, USA.
FAU - Paguia, Richard
AU  - Paguia R
AD  - Infectious Diseases, Creighton University Medical Center, Omaha, USA.
FAU - Horne, John
AU  - Horne J
AD  - Infectious Diseases, Creighton University Medical Center, Omaha, USA.
FAU - Velagapudi, Manasa
AU  - Velagapudi M
AD  - Infectious Diseases, Creighton University Medical Center, Omaha, USA.
LA  - eng
PT  - Case Reports
DEP - 20190510
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC6623995
OTO - NOTNLM
OT  - aseptic meningitis
OT  - headache
OT  - hhv-6
OT  - idiopathic intracranial hypertension
OT  - immunocompetent
OT  - nucleic acid amplification testing
OT  - pseudotumor cerebri
OT  - roseola
OT  - viral
COIS- The authors have declared that no competing interests exist.
EDAT- 2019/07/18 06:00
MHDA- 2019/07/18 06:01
PMCR- 2019/05/10
CRDT- 2019/07/18 06:00
PHST- 2019/07/18 06:00 [entrez]
PHST- 2019/07/18 06:00 [pubmed]
PHST- 2019/07/18 06:01 [medline]
PHST- 2019/05/10 00:00 [pmc-release]
AID - 10.7759/cureus.4636 [doi]
PST - epublish
SO  - Cureus. 2019 May 10;11(5):e4636. doi: 10.7759/cureus.4636.