PMID- 31316373 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1663-4365 (Print) IS - 1663-4365 (Electronic) IS - 1663-4365 (Linking) VI - 11 DP - 2019 TI - Long Term Cosmetic Application Improves Tactile Discrimination in the Elderly; a New Psychophysical Approach. PG - 164 LID - 10.3389/fnagi.2019.00164 [doi] LID - 164 AB - Introduction: Tactile sensitivity is impaired in older adults, which contributes to the loss of manual dexterity and mobility function. The reliability of classical psychophysical tests, such as two-point gap discrimination, has been questioned. Here we tested a new method to determine tactile acuity during dynamic touch, which is more functional than static touch. The aim was to validate a method providing a high level of discrimination of tactile acuity in the elderly. Methods: We tested the ability of subjects to evaluate the distance between bands printed on poly-methyl-methacrylate (PMMA) sheets. Pairs of sheets were compared in two groups of participants aged from 60 to 74 years; the test group was required to apply a cosmetic foam with an active ingredient on both their hands twice a day for 1 month, the control group had an identical task but used the same cosmetic foam without any active ingredient. The tests were run in a double-blind, placebo-controlled study. Results: The tactile discrimination threshold decreased by 83 mum after 1 month of cosmetic application in the group using the active ingredient, while it was unchanged in the control group. Discussion: The test presented here provided highly accurate results and should be useful to determine tactile performance. It allows the monitoring of tactile rehabilitation and/or skin treatments used to restore tactile acuity in the elderly. FAU - Aimonetti, Jean-Marc AU - Aimonetti JM AD - Aix Marseille University, CNRS, Laboratoire de Neurosciences Sensorielles et Cognitives (LNSC), SFR3C, Marseille, France. FAU - Deshayes, Claire AU - Deshayes C AD - Aix Marseille University, CNRS, Laboratoire de Neurosciences Sensorielles et Cognitives (LNSC), SFR3C, Marseille, France. FAU - Crest, Marcel AU - Crest M AD - Aix Marseille University, CNRS, LNC, SFR3C, Marseille, France. FAU - Cornuault, Pierre-Henri AU - Cornuault PH AD - Femto-ST Institute, Department of Applied Mechanics, University Bourgogne-Franche-Comte, CNRS/ENSMM/UFC/UTBM, Besancon, France. FAU - Weiland, Benjamin AU - Weiland B AD - Femto-ST Institute, Department of Applied Mechanics, University Bourgogne-Franche-Comte, CNRS/ENSMM/UFC/UTBM, Besancon, France. FAU - Ribot-Ciscar, Edith AU - Ribot-Ciscar E AD - Aix Marseille University, CNRS, Laboratoire de Neurosciences Sensorielles et Cognitives (LNSC), SFR3C, Marseille, France. LA - eng PT - Journal Article DEP - 20190628 PL - Switzerland TA - Front Aging Neurosci JT - Frontiers in aging neuroscience JID - 101525824 PMC - PMC6609883 OTO - NOTNLM OT - cosmetic OT - haptic touch OT - psychophysics OT - skin aging OT - tactile discrimination EDAT- 2019/07/19 06:00 MHDA- 2019/07/19 06:01 PMCR- 2019/01/01 CRDT- 2019/07/19 06:00 PHST- 2019/03/22 00:00 [received] PHST- 2019/06/13 00:00 [accepted] PHST- 2019/07/19 06:00 [entrez] PHST- 2019/07/19 06:00 [pubmed] PHST- 2019/07/19 06:01 [medline] PHST- 2019/01/01 00:00 [pmc-release] AID - 10.3389/fnagi.2019.00164 [doi] PST - epublish SO - Front Aging Neurosci. 2019 Jun 28;11:164. doi: 10.3389/fnagi.2019.00164. eCollection 2019.