PMID- 31321024
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231012
IS  - 2042-0986 (Print)
IS  - 2042-0994 (Electronic)
IS  - 2042-0986 (Linking)
VI  - 10
DP  - 2019
TI  - Pharmacist-assisted electronic prescribing at the time of admission to an 
      inpatient orthopaedic unit and its impact on medication errors: a pre- and 
      postintervention study.
PG  - 2042098619863985
LID - 10.1177/2042098619863985 [doi]
LID - 2042098619863985
AB  - BACKGROUND: Prescribing and administration errors related to pre-admission 
      medications are common amongst orthopaedic inpatients. Postprescribing medication 
      reconciliation by clinical pharmacists after hospital admission prevents some but 
      not all errors from reaching the patient. Involving pharmacists at the 
      prescribing stage may more effectively prevent errors. The aim of the study was 
      to evaluate the effect of pharmacist-assisted electronic prescribing at the time 
      of hospital admission on medication errors in orthopaedic inpatients. METHODS: A 
      pre- and postintervention study was conducted in the orthopaedic unit of a major 
      metropolitan Australian hospital. During the 10-week intervention phase, a 
      project pharmacist used electronic prescribing to assist with prescribing 
      admission medications and postoperative venous thromboembolism (VTE) prophylaxis, 
      in consultation with orthopaedic medical officers. The primary endpoint was the 
      number of medication errors per patient within 72 h of admission. Secondary 
      endpoints included the number and consequence of adverse events (AEs) associated 
      with admission medication errors and the time delay in administering VTE 
      prophylaxis after elective surgery (number of hours after recommended 
      postoperative dose-time). RESULTS: A total of 198 and 210 patients, pre- and 
      postintervention, were evaluated, respectively. The median number of admission 
      medication errors per patient declined from six pre-intervention to one 
      postintervention (p < 0.01). A total of 17 AEs were related to admission 
      medication errors during the pre-intervention period compared with 1 
      postintervention. There were 54 and 63 elective surgery patients pre- and 
      postintervention, respectively. The median delay in administering VTE prophylaxis 
      for these patients declined from 9 h pre-intervention to 2 h postintervention 
      (p < 0.01). CONCLUSIONS: Pharmacist-assisted electronic prescribing reduced the 
      number of admission medication errors and associated AEs.
FAU - Tran, Tim
AU  - Tran T
AUID- ORCID: 0000-0002-2924-3466
AD  - Pharmacy Department, Austin Health, 145 Studley Road, Heidelberg, Victoria 3084, 
      Australia.
FAU - Taylor, Simone E
AU  - Taylor SE
AD  - Pharmacy Department, Austin Health, Heidelberg, Victoria, Australia.
FAU - Hardidge, Andrew
AU  - Hardidge A
AD  - Orthopaedic Surgery, Austin Health, Heidelberg, Victoria, Australia.
FAU - Mitri, Elise
AU  - Mitri E
AD  - Pharmacy Department, Austin Health, Heidelberg, Victoria, Australia.
FAU - Aminian, Parnaz
AU  - Aminian P
AD  - Pharmacy Department, Austin Health, Heidelberg, Victoria, Australia.
FAU - George, Johnson
AU  - George J
AD  - Centre for Medicine Use and Safety, Monash University, Parkville, Victoria, 
      Australia.
FAU - Elliott, Rohan A
AU  - Elliott RA
AD  - Pharmacy Department, Austin Health, Heidelberg, Victoria, Australia, and Centre 
      for Medicine Use and Safety, Monash University, Parkville, Victoria, Australia.
LA  - eng
PT  - Journal Article
DEP - 20190712
PL  - England
TA  - Ther Adv Drug Saf
JT  - Therapeutic advances in drug safety
JID - 101549074
PMC - PMC6628525
OTO - NOTNLM
OT  - adverse drug events
OT  - electronic prescribing
OT  - medication errors
OT  - medication reconciliation
OT  - medication safety
OT  - orthopaedics
OT  - pharmacist
COIS- Conflict of interest statement: The authors declare no conflicts of interest in 
      preparing this article.
EDAT- 2019/07/20 06:00
MHDA- 2019/07/20 06:01
PMCR- 2019/07/12
CRDT- 2019/07/20 06:00
PHST- 2019/01/23 00:00 [received]
PHST- 2019/06/25 00:00 [accepted]
PHST- 2019/07/20 06:00 [entrez]
PHST- 2019/07/20 06:00 [pubmed]
PHST- 2019/07/20 06:01 [medline]
PHST- 2019/07/12 00:00 [pmc-release]
AID - 10.1177_2042098619863985 [pii]
AID - 10.1177/2042098619863985 [doi]
PST - epublish
SO  - Ther Adv Drug Saf. 2019 Jul 12;10:2042098619863985. doi: 
      10.1177/2042098619863985. eCollection 2019.