PMID- 31324981
OWN - NLM
STAT- MEDLINE
DCOM- 20200824
LR  - 20200824
IS  - 1432-198X (Electronic)
IS  - 0931-041X (Linking)
VI  - 34
IP  - 11
DP  - 2019 Nov
TI  - Ultrasound dilution and thermodilution versus color Doppler ultrasound for 
      arteriovenous fistula assessment in children on hemodialysis.
PG  - 2381-2387
LID - 10.1007/s00467-019-04297-5 [doi]
AB  - BACKGROUND: This study is aimed at comparing ultrasound dilution (UD) and 
      thermodilution (TD) with color Doppler ultrasound (CDU) for arteriovenous fistula 
      (AVF) assessment in children on hemodialysis (HD). MATERIAL AND METHODS: All 
      patients were dialysed with the Fresenius 5008 HD machine. UD was performed using 
      the Transonic device. The two methods were compared with CDU performed on a 
      non-HD day. AVF flow rate was expressed as ml/min/1.73 m(2). RESULTS: Sixteen 
      measurements of AVF flow rate and recirculation with UD and TD were compared with 
      CDU in 16 patients with a median weight of 39 kg. Both UD and TD overestimated 
      AVF flow rate when compared with CDU (+437 (95% CI + 200, + 674) and + 476 (95% 
      CI + 80, + 871) ml/min/1.73 m(2) for UD and TD, respectively). CDU flow rate was 
      significantly correlated to UD flow rate (r(2) = 0.761, p < 0.001), but not to TD 
      flow rate (r(2) = 0.164, p = 0.120). Although recirculation in all AVF was 
      estimated to be 0% and < 15% with UD and TD, respectively, 7 significant stenoses 
      were diagnosed by CDU. AVF with stenosis had lower flow rates when measured by 
      CDU, UD or TD, but only CDU measurements reached statistical significance 
      (p = 0.008, p = 0.142 and p = 0.174, respectively). CONCLUSION: UD and TD 
      overestimate AVF flow rate when compared with CDU, which is the most reliable 
      non-invasive method for screening vascular access for stenosis. UD seems more 
      accurate than TD for AVF flow rate assessment. Recirculation via UD or TD should 
      not be used for early screening of AVF stenosis in children on HD.
FAU - Karava, Vasiliki
AU  - Karava V
AD  - Pediatric Nephrology Department, Robert Debre Hospital, APHP, Paris, France. 
      vasilikikarava@hotmail.fr.
FAU - Kwon, Theresa
AU  - Kwon T
AD  - Pediatric Nephrology Department, Robert Debre Hospital, APHP, Paris, France.
FAU - Franco, Gilbert
AU  - Franco G
AD  - Angiology Department, Arago Clinic, Paris, France.
FAU - Georges, Deschenes
AU  - Georges D
AD  - Pediatric Nephrology Department, Robert Debre Hospital, APHP, Paris, France.
FAU - Macher, Marie-Alice
AU  - Macher MA
AD  - Pediatric Nephrology Department, Robert Debre Hospital, APHP, Paris, France.
FAU - Hogan, Julien
AU  - Hogan J
AD  - Pediatric Nephrology Department, Robert Debre Hospital, APHP, Paris, France.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20190719
PL  - Germany
TA  - Pediatr Nephrol
JT  - Pediatric nephrology (Berlin, Germany)
JID - 8708728
SB  - IM
MH  - Adolescent
MH  - Arteriovenous Shunt, Surgical/*adverse effects
MH  - Child
MH  - Cross-Sectional Studies
MH  - Female
MH  - Graft Occlusion, Vascular/*diagnostic imaging/etiology
MH  - Humans
MH  - Kidney Failure, Chronic
MH  - Male
MH  - Regional Blood Flow
MH  - Renal Dialysis/*adverse effects/methods
MH  - Thermodilution
MH  - Ultrasonography, Doppler, Color
OTO - NOTNLM
OT  - AVF
OT  - Color Doppler ultrasound
OT  - Pediatric
OT  - Thermodilution
OT  - Ultrasound dilution
EDAT- 2019/07/22 06:00
MHDA- 2020/08/25 06:00
CRDT- 2019/07/21 06:00
PHST- 2019/01/13 00:00 [received]
PHST- 2019/06/13 00:00 [accepted]
PHST- 2019/04/26 00:00 [revised]
PHST- 2019/07/22 06:00 [pubmed]
PHST- 2020/08/25 06:00 [medline]
PHST- 2019/07/21 06:00 [entrez]
AID - 10.1007/s00467-019-04297-5 [pii]
AID - 10.1007/s00467-019-04297-5 [doi]
PST - ppublish
SO  - Pediatr Nephrol. 2019 Nov;34(11):2381-2387. doi: 10.1007/s00467-019-04297-5. Epub 
      2019 Jul 19.