PMID- 31330062
OWN - NLM
STAT- MEDLINE
DCOM- 20200902
LR  - 20200902
IS  - 1440-1681 (Electronic)
IS  - 0305-1870 (Linking)
VI  - 46
IP  - 11
DP  - 2019 Nov
TI  - Potential roles of chromium on inflammatory biomarkers in diabetes: A Systematic.
PG  - 975-983
LID - 10.1111/1440-1681.13144 [doi]
AB  - Diabetes, as a low-grade chronic inflammatory disease, causes disruption in 
      proper function of immune and metabolic system. Chromium is an important element 
      required for normal lipid and glucose metabolism. Chromium deficiency is 
      correlated with elevation in cardiometabolic risk, which results from increased 
      inflammation. This systematic review was conducted to discover the potential 
      roles of chromium on inflammatory biomarkers. Eligible studies were all in vitro, 
      animal and human studies published in English-language journals from inception 
      until October 2018. PubMed, Scopus, Embase, ProQuest and Google Scholar databases 
      were searched to fined interventional studies from the effects of chromium on 
      inflammatory biomarkers such as tumour necrosis factor a (TNF-a), C-reactive 
      protein (CRP), interleukins, monocyte chemoattractant protein-1 (MCP-1), 
      intercellular adhesion molecule-1 (ICAM-1) and adipocytokines in hyperglycaemia 
      and diabetes. Out of 647 articles found in the search, only 14 articles were 
      eligible for analysis, three in vitro studies, eight animal studies and three 
      human studies. Twelve of the 14 studies included in this review, chromium 
      significantly decreased inflammatory factors. The findings of this review 
      indicate, based on in vitro and in vivo studies, that chromium might have 
      potential anti-inflammatory properties, but some of the studies did not show 
      anti-inflammatory effects for chromium (two studies). There are only three 
      studies in humans with controversial results. Therefore, more consistent 
      randomized double-blind controlled trials are needed to reach relevant clinical 
      recommendations, as well as to determine the precise mechanism, of chromium on 
      inflammation in diabetes.
CI  - (c) 2019 John Wiley & Sons Australia, Ltd.
FAU - Moradi, Fardin
AU  - Moradi F
AD  - Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, 
      Tabriz, Iran.
FAU - Maleki, Vahid
AU  - Maleki V
AUID- ORCID: 0000-0002-5772-3395
AD  - Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, 
      Tabriz, Iran.
FAU - Saleh-Ghadimi, Sevda
AU  - Saleh-Ghadimi S
AUID- ORCID: 0000-0001-7709-4939
AD  - Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, 
      Tabriz, Iran.
FAU - Kooshki, Fatemeh
AU  - Kooshki F
AD  - Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, 
      Tabriz, Iran.
FAU - Pourghassem Gargari, Bahram
AU  - Pourghassem Gargari B
AUID- ORCID: 0000-0001-7667-099X
AD  - Nutrition Research Centre, Faculty of Nutrition and Food Sciences, Tabriz 
      University of Medical Sciences, Tabriz, Iran.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
DEP - 20190816
PL  - Australia
TA  - Clin Exp Pharmacol Physiol
JT  - Clinical and experimental pharmacology & physiology
JID - 0425076
RN  - 0 (Biomarkers)
RN  - 0R0008Q3JB (Chromium)
SB  - IM
MH  - Animals
MH  - Biomarkers/metabolism
MH  - Chromium/*metabolism
MH  - Diabetes Mellitus/*metabolism
MH  - Humans
MH  - Inflammation/metabolism
OTO - NOTNLM
OT  - chromium
OT  - diabetes mellitus
OT  - inflammation
OT  - systematic review
EDAT- 2019/07/23 06:00
MHDA- 2020/09/04 06:00
CRDT- 2019/07/23 06:00
PHST- 2019/02/19 00:00 [received]
PHST- 2019/07/16 00:00 [revised]
PHST- 2019/07/17 00:00 [accepted]
PHST- 2019/07/23 06:00 [pubmed]
PHST- 2020/09/04 06:00 [medline]
PHST- 2019/07/23 06:00 [entrez]
AID - 10.1111/1440-1681.13144 [doi]
PST - ppublish
SO  - Clin Exp Pharmacol Physiol. 2019 Nov;46(11):975-983. doi: 
      10.1111/1440-1681.13144. Epub 2019 Aug 16.