PMID- 31330408
OWN - NLM
STAT- MEDLINE
DCOM- 20191022
LR  - 20191022
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 182
DP  - 2019 Oct 30
TI  - Residue determination of pyraclostrobin, picoxystrobin and its metabolite in 
      pepper fruit via UPLC-MS/MS under open field conditions.
PG  - 109445
LID - S0147-6513(19)30776-6 [pii]
LID - 10.1016/j.ecoenv.2019.109445 [doi]
AB  - In this study, a new, high-efficiency and sensitive method was determined to 
      simultaneous analyze the residue of pyraclostrobin, picoxystrobin and its 
      metabolite BF-500-3 in pepper fruit using modified QuEChERS pretreatment combined 
      with ultra performance liquid chromatography-tandem mass spectrometry. The 
      clean-up steps of QuEChERS procedure were optimized using the chemometric tools. 
      Models of stepwise regression and surface response demonstrated that the optimal 
      sorbent mixtures were 40 mg nano-zirconia + 10 mg C(18) for pyraclostrobin and 
      picoxystrobin and 30 mg nano-zirconia + 20 mg C(18) for BF-500-3. The optimized 
      purification procedures provided satisfactory recoveries for all tested 
      fungicides with rates between 91% and 107% and relative standard deviations 
      between 3.7% and 9.6%. The limits of detection and quantification were in the 
      range of 0.0360-0.272 mug/kg and 0.120-0.910 mug/kg. Based on this method, the 
      dissipation of pyraclostrobin, picoxystrobin and its metabolite in pepper fruit 
      were determined under field conditions. Pyraclostrobin and picoxystrobin degraded 
      rapidly with half-lives of 5.53-7.02 and 5.97-7.82 days and 5.09 and 5.68 days in 
      2016 and 2017, respectively. The residue levels of BF-500-3 increased first and 
      then decreased. The terminal residues of all fungicides were below the maximum 
      residue limits (MRLs). This research can not only provide guidance for the 
      reasonable usage of pyraclostrobin and picoxystrobin in agriculture but also give 
      a reference for the Chinese government to establish the MRL for pyraclostrobin in 
      pepper.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Gao, Yangyang
AU  - Gao Y
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China.
FAU - Yang, Song
AU  - Yang S
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China.
FAU - Li, Xiaoxu
AU  - Li X
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China.
FAU - He, Lifei
AU  - He L
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China.
FAU - Zhu, Jiamei
AU  - Zhu J
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China.
FAU - Mu, Wei
AU  - Mu W
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China.
FAU - Liu, Feng
AU  - Liu F
AD  - Shandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect 
      Pests, Shandong Agricultural University, Tai'an, Shandong, 271018, PR China; 
      College of Plant Protection, Shandong Agricultural University, Tai'an, Shandong, 
      271018, PR China. Electronic address: fliu@sdau.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20190719
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticide Residues)
RN  - 0 (Strobilurins)
RN  - 62DH7GEL1P (picoxystrobin)
RN  - DJW8M9OX1H (pyrachlostrobin)
SB  - IM
MH  - Agriculture
MH  - Chromatography, Liquid/methods
MH  - Fruit/chemistry
MH  - Fungicides, Industrial/*analysis
MH  - Pesticide Residues/*analysis
MH  - Strobilurins/*analysis
MH  - Tandem Mass Spectrometry/methods
MH  - Vegetables/*chemistry
OTO - NOTNLM
OT  - Chemometric tools
OT  - Metabolite
OT  - Pepper
OT  - Picoxystrobin
OT  - Pyraclostrobin
EDAT- 2019/07/23 06:00
MHDA- 2019/10/23 06:00
CRDT- 2019/07/23 06:00
PHST- 2019/05/09 00:00 [received]
PHST- 2019/07/01 00:00 [revised]
PHST- 2019/07/11 00:00 [accepted]
PHST- 2019/07/23 06:00 [pubmed]
PHST- 2019/10/23 06:00 [medline]
PHST- 2019/07/23 06:00 [entrez]
AID - S0147-6513(19)30776-6 [pii]
AID - 10.1016/j.ecoenv.2019.109445 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2019 Oct 30;182:109445. doi: 
      10.1016/j.ecoenv.2019.109445. Epub 2019 Jul 19.